A Bayesian Approach for Selecting Relevant External Data (BASE): Application to a study of Long-Term Outcomes in a Hemophilia Gene Therapy Trial

Kavli Affiliate: Xiang Zhang | First 5 Authors: Tianyu Pan, Xiang Zhang, Weining Shen, Ting Ye, | Summary: Gene therapies aim to address the root causes of diseases, particularly those stemming from rare genetic defects that can be life-threatening or severely debilitating. While there has been notable progress in the development of gene therapies in […]


Continue.. A Bayesian Approach for Selecting Relevant External Data (BASE): Application to a study of Long-Term Outcomes in a Hemophilia Gene Therapy Trial

Extended Spreading of Saline Droplets upon Impact on a Frosty Surface

Kavli Affiliate: Feng Wang | First 5 Authors: Hao Zeng, Feng Wang, Chao Sun, , | Summary: Understanding the solidification dynamics of impacted water droplets is fundamental and crucial for applications, especially with the presence of frost and salt. Here, we experimentally investigate the spreading and freezing dynamics of saline droplets upon impact on a […]


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Metric Ion Classification (MIC): A deep learning tool for assigning ions and waters in cryo-EM and x-ray crystallography structures

Kavli Affiliate: Michael Keiser | Authors: Laura Shub, Wenjin Liu, Georgios Skiniotis, Michael J. Keiser and Michael J. Robertson | Summary: At sufficiently high resolution, x-ray crystallography and cryogenic electron microscopy are capable of resolving small spherical map features corresponding to either water or ions. Correct classification of these sites provides crucial insight for understanding […]


Continue.. Metric Ion Classification (MIC): A deep learning tool for assigning ions and waters in cryo-EM and x-ray crystallography structures

Automatic Summarization of Doctor-Patient Encounter Dialogues Using Large Language Model through Prompt Tuning

Kavli Affiliate: Cheng Peng | First 5 Authors: Mengxian Lyu, Cheng Peng, Xiaohan Li, Patrick Balian, Jiang Bian | Summary: Automatic text summarization (ATS) is an emerging technology to assist clinicians in providing continuous and coordinated care. This study presents an approach to summarize doctor-patient dialogues using generative large language models (LLMs). We developed prompt-tuning […]


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Chemical Diversity on Small Scales — Abundance Analysis of the Tucana V Ultra-Faint Dwarf Galaxy

Kavli Affiliate: Alexander P. Ji | First 5 Authors: Terese T. Hansen, Joshua D. Simon, Ting S. Li, Domani Sharkey, Alexander P. Ji | Summary: The growing number of Milky Way satellites detected in recent years has introduced a new focus for stellar abundance analysis. Abundances of stars in satellites have been used to probe […]


Continue.. Chemical Diversity on Small Scales — Abundance Analysis of the Tucana V Ultra-Faint Dwarf Galaxy

Chronic Ethanol Exposure Produces Persistent Impairment in Cognitive Flexibility and Decision Signals in the Striatum

Kavli Affiliate: Daeyeol Lee and Patricia Janak | Authors: Yifeng Cheng, Robin Magnard, Angela Langdon, Daeyeol Lee and Patricia H. Janak | Summary: Value-based decision-making relies on the striatum, where neural plasticity can be altered by chronic ethanol (EtOH) exposure, but the effects of such plasticity on striatal neural dynamics during decision-making remain unclear. This […]


Continue.. Chronic Ethanol Exposure Produces Persistent Impairment in Cognitive Flexibility and Decision Signals in the Striatum

In-Hand Following of Deformable Linear Objects Using Dexterous Fingers with Tactile Sensing

Kavli Affiliate: Xiang Zhang | First 5 Authors: Mingrui Yu, Boyuan Liang, Xiang Zhang, Xinghao Zhu, Lingfeng Sun | Summary: Most research on deformable linear object (DLO) manipulation assumes rigid grasping. However, beyond rigid grasping and re-grasping, in-hand following is also an essential skill that humans use to dexterously manipulate DLOs, which requires continuously changing […]


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In-Hand Following of Deformable Linear Objects Using Dexterous Fingers with Tactile Sensing

Kavli Affiliate: Xiang Zhang | First 5 Authors: Mingrui Yu, Boyuan Liang, Xiang Zhang, Xinghao Zhu, Xiang Li | Summary: Most research on deformable linear object (DLO) manipulation assumes rigid grasping. However, beyond rigid grasping and re-grasping, in-hand following is also an essential skill that humans use to dexterously manipulate DLOs, which requires continuously changing […]


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Intention Action Anticipation Model with Guide-Feedback Loop Mechanism

Kavli Affiliate: Fuchun Zhang | First 5 Authors: Zongnan Ma, Fuchun Zhang, Zhixiong Nan, Yao Ge, | Summary: Anticipating human intention from videos has broad applications, such as automatic driving, robot assistive technology, and virtual reality. This study addresses the problem of intention action anticipation using egocentric video sequences to estimate actions that indicate human […]


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Improving Generalizability of Extracting Social Determinants of Health Using Large Language Models through Prompt-tuning

Kavli Affiliate: Cheng Peng | First 5 Authors: Cheng Peng, Zehao Yu, Kaleb E Smith, Wei-Hsuan Lo-Ciganic, Jiang Bian | Summary: The progress in natural language processing (NLP) using large language models (LLMs) has greatly improved patient information extraction from clinical narratives. However, most methods based on the fine-tuning strategy have limited transfer learning ability […]


Continue.. Improving Generalizability of Extracting Social Determinants of Health Using Large Language Models through Prompt-tuning