A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes

Kavli Affiliate: Shawn Ferguson | Authors: Amanda Bentley-DeSousa and Shawn Ferguson | Summary: Mutations that increase LRRK2 kinase activity have been linked to Parkinson’s disease and Crohn’s disease. LRRK2 is also activated by lysosome damage evoked by chemical and pathogenic stimuli. However, the endogenous cellular mechanisms that control LRRK2 kinase activity are not well understood. […]


Continue.. A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes

Confirming the Tidal Tails of the Young Open Cluster Blanco 1 with TESS Rotation Periods

Kavli Affiliate: Andrew M. Vanderburg | First 5 Authors: Lizhou Sha, Andrew M. Vanderburg, Luke G. Bouma, Chelsea X. Huang, | Summary: Blanco 1 is an $approx 130,mathrm{Myr}$ open cluster located 240 pc from the Sun below the Galactic plane. Recent studies have reported the existence of diffuse tidal tails extending 50-60 pc from the […]


Continue.. Confirming the Tidal Tails of the Young Open Cluster Blanco 1 with TESS Rotation Periods

Low-energy critical behavior in two-dimensional tilted semi-Dirac semimetals driven by fermion-fermion interactions

Kavli Affiliate: Jing Wang | First 5 Authors: Wen Liu, Wen-Hao Bian, Xiao-Zhuo Chu, Jing Wang, | Summary: Employing the renormalization group approach, we carefully investigate the critical behavior of two-dimensional tilted semi-Dirac semimetals induced by the fermion-fermion interactions in the low-energy regime. After incorporating all one-loop corrections, we derive the coupled RG equations of […]


Continue.. Low-energy critical behavior in two-dimensional tilted semi-Dirac semimetals driven by fermion-fermion interactions

A Post-Starburst Pathway to Forming Massive Galaxies and Their Black Holes at z>6

Kavli Affiliate: John D. Silverman | First 5 Authors: Masafusa Onoue, Xuheng Ding, John D. Silverman, Yoshiki Matsuoka, Takuma Izumi | Summary: Understanding the rapid formation of supermassive black holes (SMBHs) in the early universe requires an understanding of how stellar mass grows in the host galaxies. Here, we perform an analysis of rest-frame optical […]


Continue.. A Post-Starburst Pathway to Forming Massive Galaxies and Their Black Holes at z>6

RSVP for VPSA : A Meta Design Study on Rapid Suggestive Visualization Prototyping for Visual Parameter Space Analysis

Kavli Affiliate: Michael Wimmer | First 5 Authors: Manfred Klaffenboeck, Michael Gleicher, Johannes Sorger, Michael Wimmer, Torsten Möller | Summary: Visual Parameter Space Analysis (VPSA) enables domain scientists to explore input-output relationships of computational models. Existing VPSA applications often feature multi-view visualizations designed by visualization experts for a specific scenario, making it hard for domain […]


Continue.. RSVP for VPSA : A Meta Design Study on Rapid Suggestive Visualization Prototyping for Visual Parameter Space Analysis

The K2 and TESS Synergy III: search and rescue of the lost ephemeris for K2’s first planet

Kavli Affiliate: Andrew Vanderburg | First 5 Authors: Erica Thygesen, Joseph E. Rodriguez, Zoë L. De Beurs, Andrew Vanderburg, John H. Livingston | Summary: K2-2 b/HIP 116454 b, the first exoplanet discovery by K2 during its Two-Wheeled Concept Engineering Test, is a sub-Neptune (2.5 $pm$ 0.1 $R_oplus$, 9.7 $pm$ 1.2 $M_oplus$) orbiting a relatively bright […]


Continue.. The K2 and TESS Synergy III: search and rescue of the lost ephemeris for K2’s first planet

Improving Anomalous Sound Detection via Low-Rank Adaptation Fine-Tuning of Pre-Trained Audio Models

Kavli Affiliate: Jia Liu | First 5 Authors: Xinhu Zheng, Anbai Jiang, Bing Han, Yanmin Qian, Pingyi Fan | Summary: Anomalous Sound Detection (ASD) has gained significant interest through the application of various Artificial Intelligence (AI) technologies in industrial settings. Though possessing great potential, ASD systems can hardly be readily deployed in real production sites […]


Continue.. Improving Anomalous Sound Detection via Low-Rank Adaptation Fine-Tuning of Pre-Trained Audio Models

The Blending ToolKit: A simulation framework for evaluation of galaxy detection and deblending

Kavli Affiliate: Patricia Burchat | First 5 Authors: Ismael Mendoza, Andrii Torchylo, Thomas Sainrat, Axel Guinot, Alexandre Boucaud | Summary: We present an open source Python library for simulating overlapping (i.e., blended) images of galaxies and performing self-consistent comparisons of detection and deblending algorithms based on a suite of metrics. The package, named Blending Toolkit […]


Continue.. The Blending ToolKit: A simulation framework for evaluation of galaxy detection and deblending

Voltage Mining for (De)lithiation-stabilized Cathodes and a Machine Learning Model for Li-ion Cathode Voltage

Kavli Affiliate: Kristin A. Persson | First 5 Authors: Haoming Howard Li, Qian Chen, Gerbrand Ceder, Kristin A. Persson, | Summary: Advances in lithium-metal anodes have inspired interest in discovery of Li-free cathodes, most of which are natively found in their charged state. This is in contrast to today’s commercial lithium-ion battery cathodes, which are […]


Continue.. Voltage Mining for (De)lithiation-stabilized Cathodes and a Machine Learning Model for Li-ion Cathode Voltage