Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C

Posted by dbos Yale

Kavli Affiliate: Pietro De Camilli; | Authors: Xinbo Wang, Peng Xu, Amanda Bentley-DeSousa, William Hancock-Cerutti, Shujun Cai, Benjamin T Johnson, Francesca Tonelli, Gabriel Talaia, Dario R Alessi, Shawn M Ferguson and Pietro De Camilli | Summary: Based on genetic studies, lysosome dysfunction is thought to play a pathogenetic role in Parkinson’s disease (PD). Here we […]


Continue.. Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C

The ventral CA2 region of the hippocampus and its differential contributions to social memory and social aggression

Posted by dbos Columbia

Kavli Affiliate: Steven Siegelbaum; | Authors: Lara M. Boyle, Wanhui Sheng, Felix Leroy, Rhea Sahai, Sarah Irfan, Heon-Jin Lee, Andres Villegas, W. Scott Young and Steven A Siegelbaum | Summary: Although it is well-known that the hippocampus mediates declarative memory (the repository of information of people, places, things and events) and influences behavior, the differential […]


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RESPAN: an accurate, unbiased and automated pipeline for analysis of dendritic morphology and dendritic spine mapping

Posted by dbos Columbia

Kavli Affiliate: Franck Polleux; | Authors: Sergio B. Garcia, Alexa P. Schlotter, Daniela Pereira, Franck Polleux and Luke Hammond | Summary: Accurate and unbiased reconstructions of neuronal morphology, including quantification of dendritic spine morphology and distribution, are widely used in neuroscience but remain a major roadblock for large-scale analysis. Traditionally, spine analysis has required labor-intensive […]


Continue.. RESPAN: an accurate, unbiased and automated pipeline for analysis of dendritic morphology and dendritic spine mapping

Disruption of Core Stress Granule Protein Aggregates Promotes CNS Axon Regeneration

Posted by dbos UCSD / Salk

Kavli Affiliate: Mark H. Tuszynski; | Authors: Pabitra K Sahoo, Nick Hanovice, Patricia Ward, Manasi A Agrawal, Terika P Smith, HaoMin SiMa, Jennifer N Dulin, Lauren S Vaughn, Mark Tuszynski, Kristy Welshhans, Larry Benowitz, Arthur English, John D Houle and Jeffery L Twiss | Summary: Depletion or inhibition of core stress granule proteins, G3BP1 in […]


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TESS Hunt for Young and Maturing Exoplanets (THYME) X: a two-planet system in the 210 Myr MELANGE-5 Association

Posted by dbos MIT

Kavli Affiliate: Andrew Vanderburg | First 5 Authors: Pa Chia Thao, Andrew W. Mann, Madyson G. Barber, Adam L. Kraus, Benjamin M. Tofflemire | Summary: Young (<500 Myr) planets are critical to studying how planets form and evolve. Among these young planetary systems, multi-planet configurations are particularly useful as they provide a means to control […]


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TESS Hunt for Young and Maturing Exoplanets (THYME) X: a two-planet system in the 210 Myr MELANGE-5 Association

Posted by dbos MIT

Kavli Affiliate: George R. Ricker | First 5 Authors: Pa Chia Thao, Andrew W. Mann, Madyson G. Barber, Adam L. Kraus, Benjamin M. Tofflemire | Summary: Young (<500 Myr) planets are critical to studying how planets form and evolve. Among these young planetary systems, multi-planet configurations are particularly useful as they provide a means to […]


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The JADES Transient Survey: Discovery and Classification of Supernovae in the JADES Deep Field

Posted by dbos Cambridge

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Christa DeCoursey, Eiichi Egami, Justin D. R. Pierel, Fengwu Sun, Armin Rest | Summary: The JWST Advanced Deep Extragalactic Survey (JADES) is a multi-cycle JWST program that has taken among the deepest near-/mid-infrared images to date (down to $sim$30 ABmag) over $sim$25 arcmin$^2$ in the GOODS-S field […]


Continue.. The JADES Transient Survey: Discovery and Classification of Supernovae in the JADES Deep Field

The JADES Transient Survey: Discovery and Classification of Supernovae in the JADES Deep Field

Posted by dbos Cambridge

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Christa DeCoursey, Eiichi Egami, Justin D. R. Pierel, Fengwu Sun, Armin Rest | Summary: The JWST Advanced Deep Extragalactic Survey (JADES) is a multi-cycle JWST program that has taken among the deepest near-infrared images to date (down to $sim$30.5 ABmag) over $sim$25 arcmin$^2$ in the GOODS-S field […]


Continue.. The JADES Transient Survey: Discovery and Classification of Supernovae in the JADES Deep Field

The JADES Transient Survey: Discovery and Classification of Supernovae in the JADES Deep Field

Posted by dbos Cambridge

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Christa DeCoursey, Eiichi Egami, Justin D. R. Pierel, Fengwu Sun, Armin Rest | Summary: The JWST Advanced Deep Extragalactic Survey (JADES) is a multi-cycle JWST program that has taken among the deepest near-infrared images to date (down to $sim$30.5 ABmag) over $sim$25 arcmin$^2$ in the GOODS-S field […]


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Programmable Multi-responsive Nanocellulose-based Hydrogels with Embodied Logic

Posted by dbos Caltech

Kavli Affiliate: Chiara Daraio | First 5 Authors: Beatriz Arsuffi, Gilberto Siqueira, Gustav Nyström, Silvia Titotto, Tommaso Magrini | Summary: Programmable materials are desirable for a variety of functional applications that range from biomedical devices, actuators and soft robots to adaptive surfaces and deployable structures. However, current smart materials are often designed to respond to […]


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