Kavli Affiliate: A. James Hudspeth | Authors: Camila M. Villasante, Xinyue Deng, Joel E. Cohen and A.J. Hudspeth | Summary: Mechanical force controls the opening and closing of mechanosensitive ion channels atop the hair bundles of the inner ear. The filamentous tip link connecting transduction channels to the tallest neighboring stereocilium modulates the force transmitted […]
Continue.. Nanomechanics of wild-type and mutant dimers of the tip-link protein protocadherin 15