Design principles of transcription factors with intrinsically disordered regions

Kavli Affiliate: Ariel Amir | First 5 Authors: Wencheng Ji, Ori Hachmo, Naama Barkai, Ariel Amir, | Summary: Transcription Factors (TFs) are proteins crucial for regulating gene expression. Effective regulation requires the TFs to rapidly bind to the correct target, enabling the cell to respond timely to various stimuli such as nutrient availability or toxin […]


Continue.. Design principles of transcription factors with intrinsically disordered regions

Roles of intrinsically disordered regions in transcription factor search

Kavli Affiliate: Ariel Amir | First 5 Authors: Wencheng Ji, Ori Hachmo, Naama Barkai, Ariel Amir, | Summary: Transcription Factors (TFs) are proteins that regulate gene expression. The regulation mechanism is via the binding of a TF to a specific part of the gene associated with it, the TF’s target. For the regulation to be […]


Continue.. Roles of intrinsically disordered regions in transcription factor search

X-ray/UVOIR Frequency-resolved Time Lag Analysis of Mrk 335 Reveals Accretion Disk Reprocessing

Kavli Affiliate: Erin Kara | First 5 Authors: Collin Lewin, Erin Kara, Edward M. Cackett, Dan Wilkins, Christos Panagiotou | Summary: UV and optical continuum reverberation mapping is powerful for probing the accretion disk and inner broad-line region. However, recent reverberation mapping campaigns in the X-ray, UV, and optical have found lags consistently longer than […]


Continue.. X-ray/UVOIR Frequency-resolved Time Lag Analysis of Mrk 335 Reveals Accretion Disk Reprocessing

The Third Fermi Large Area Telescope Catalog of Gamma-ray Pulsars

Kavli Affiliate: Maria Elena Monzani | First 5 Authors: David A. Smith, Philippe Bruel, Colin J. Clark, Lucas Guillemot, Matthew T. Kerr | Summary: We present 294 pulsars found in GeV data from the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope. Another 33 millisecond pulsars (MSPs) discovered in deep radio searches of […]


Continue.. The Third Fermi Large Area Telescope Catalog of Gamma-ray Pulsars

The Third Fermi Large Area Telescope Catalog of Gamma-ray Pulsars

Kavli Affiliate: Maria Elena Monzani | First 5 Authors: David A. Smith, Philippe Bruel, Colin J. Clark, Lucas Guillemot, Matthew T. Kerr | Summary: We present 294 pulsars found in GeV data from the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope. Another 33 millisecond pulsars (MSPs) discovered in deep radio searches of […]


Continue.. The Third Fermi Large Area Telescope Catalog of Gamma-ray Pulsars

Calcium-permeable AMPA receptors govern PV neuron feature selectivity

Kavli Affiliate: Dwight Bergles, Seth Blackshaw | Authors: Ingie Hong, Juhyun Kim, Thomas Hainmueller, Dong Won Kim, Richard C. Johnson, Soo Hyun Park, Nathachit Limjunyawong, Zhuonan Yang, David Cheon, Taeyoung Hwang, Amit Agarwal, Thibault Cholvin, Fenna M. Krienen, Steven A. McCarroll, Xinzhong Dong, David A. Leopold, Seth Blackshaw, Dwight E. Bergles, Marlene Bartos, Solange P. […]


Continue.. Calcium-permeable AMPA receptors govern PV neuron feature selectivity