Arrestin-3 agonism at D3 dopamine receptors defines a subclass of second generation antipsychotics that promotes drug tolerance

Posted by klaurent UCSF

Kavli Affiliate: Kevin Bender | Authors: Selin Schamiloglu, Elinor Lewis, Anne C Hergarden, Kevin Bender and Jennifer L Whistler | Summary: ABSTRACT Second generation antipsychotics (SGAs) are front-line treatments for serious mental illness. Often, individual patients benefit only from some SGAs and not others. The mechanisms underlying this unpredictability in treatment efficacy remain unclear. All […]


Continue.. Arrestin-3 agonism at D3 dopamine receptors defines a subclass of second generation antipsychotics that promotes drug tolerance

The Photon Ring in M87*

Posted by klaurent Peking

Kavli Affiliate: Lijing Shao | First 5 Authors: Avery E. Broderick, Dominic W. Pesce, Paul Tiede, Hung-Yi Pu, Roman Gold | Summary: We report measurements of the gravitationally lensed secondary image — the first in an infinite series of so-called "photon rings" — around the supermassive black hole M87* via simultaneous modeling and imaging of […]


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The Atacama Cosmology Telescope: limits on dark matter-baryon interactions from DR4 power spectra

Posted by dbos Cambridge

Kavli Affiliate: Blake Sherwin | First 5 Authors: Zack Li, Rui An, Vera Gluscevic, Kimberly K. Boddy, J. Richard Bond | Summary: Diverse astrophysical observations suggest the existence of cold dark matter that interacts only gravitationally with radiation and ordinary baryonic matter. Any nonzero coupling between dark matter and baryons would provide a significant step […]


Continue.. The Atacama Cosmology Telescope: limits on dark matter-baryon interactions from DR4 power spectra

Measurement of the $Ω_c^0$ lifetime at Belle II

Posted by klaurent Tokyo

Kavli Affiliate: T. Higuchi | First 5 Authors: Belle II Collaboration, F. Abudinén, I. Adachi, L. Aggarwal, H. Ahmed | Summary: We report on a measurement of the $Omega_c^0$ lifetime using $Omega_c^0 to Omega^-pi^+$ decays reconstructed in $e^+e^-to cbar{c}$ data collected by the Belle II experiment and corresponding to $207~{rm fb^{-1}}$ of integrated luminosity. The […]


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Internal states as a source of subject-dependent movement variability and their representation by large-scale networks

Posted by klaurent Hopkins

Kavli Affiliate: Kathleen Cullen & Sridevi Sarma | Authors: Macauley Smith Breault, Pierre Sacré, Zachary B Fitzgerald, John T Gale, Kathleen E Cullen, Jorge A González-Martínez and Sridevi V Sarma | Summary: Abstract A human’s ability to adapt and learn relies on reflecting on past performance. Such reflections form latent factors called internal states that […]


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NET-FLEET: Achieving Linear Convergence Speedup for Fully Decentralized Federated Learning with Heterogeneous Data

Posted by klaurent Tokyo

Kavli Affiliate: Jia Liu | First 5 Authors: Xin Zhang, Minghong Fang, Zhuqing Liu, Haibo Yang, Jia Liu | Summary: Federated learning (FL) has received a surge of interest in recent years thanks to its benefits in data privacy protection, efficient communication, and parallel data processing. Also, with appropriate algorithmic designs, one could achieve the […]


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SYNTHESIS: A Semi-Asynchronous Path-Integrated Stochastic Gradient Method for Distributed Learning in Computing Clusters

Posted by klaurent Tokyo

Kavli Affiliate: Jia Liu | First 5 Authors: Zhuqing Liu, Xin Zhang, Jia Liu, , | Summary: To increase the training speed of distributed learning, recent years have witnessed a significant amount of interest in developing both synchronous and asynchronous distributed stochastic variance-reduced optimization methods. However, all existing synchronous and asynchronous distributed training algorithms suffer […]


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Spin-Hall magnetoresistance in quasi-two-dimensional antiferromagnetic insulator/metal bilayer systems

Posted by klaurent UCAS

Kavli Affiliate: Mamoru Matsuo | First 5 Authors: Takuto Ishikawa, Mamoru Matsuo, Takeo Kato, , | Summary: We study the temperature dependence of spin Hall magnetoresistance (SMR) in antiferromagnetic insulator (AFI)/metal bilayer systems. We calculate the amplitude of the SMR signal by using a quantum Monte Carlo simulation and examine how the SMR depends on […]


Continue.. Spin-Hall magnetoresistance in quasi-two-dimensional antiferromagnetic insulator/metal bilayer systems

Spin-Hall Magnetoresistance in quasi-two-dimensional antiferromagnetic insulator/metal bilayer systems

Posted by klaurent UCAS

Kavli Affiliate: Mamoru Matsuo | First 5 Authors: Takuto Ishikawa, Mamoru Matsuo, Takeo Kato, , | Summary: We study temperature dependence of spin Hall magnetoresistance (SMR) in antiferromagnetic insulator (AFI)/metal bilayer systems. We calculate the amplitude of the SMR signal using the quantum Monte Carlo simulation and examine how the SMR depends on the amplitude […]


Continue.. Spin-Hall Magnetoresistance in quasi-two-dimensional antiferromagnetic insulator/metal bilayer systems