Comparative analysis of single-cell and single-nucleus RNA-sequencing in a rabbit model of retinal detachment-related proliferative vitreoretinopathy.

Kavli Affiliate: Seth Blackshaw | Authors: Clayton P. Santiago, Megan Y. Gimmen, Yuchen Lu, Minda M. McNally, Leighton H. Duncan, Tyler Creamer, Linda Orzolek, Seth Blackshaw and Mandeep Singh | Summary: Structured Abstract Purpose Proliferative vitreoretinopathy (PVR) is the most common cause of failure of retinal reattachment surgery and the molecular changes leading to this […]


Continue.. Comparative analysis of single-cell and single-nucleus RNA-sequencing in a rabbit model of retinal detachment-related proliferative vitreoretinopathy.

Structured Joint Decomposition (SJD) identifies conserved molecular dynamics across collections of biologically related multi-omics data matrices

Kavli Affiliate: Brian Caffo | Authors: Huan Chen, Jinrui Liu, Shreyash Sonthalia, Genevieve Stein-OBrien, Luo Xiao, Brian Caffo and Carlo Colantuoni | Summary: Abstract Motivation It is necessary to develop exploratory tools to learn from the unprecedented volume of high-dimensional multi-omic data currently being produced. We have developed an R package, SJD, which identifies components […]


Continue.. Structured Joint Decomposition (SJD) identifies conserved molecular dynamics across collections of biologically related multi-omics data matrices

Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing

Kavli Affiliate: V. S. Ramachandran | Authors: Paul L. Auer, Yasminka A Jakubek, Ying Zhou, Adrienne M Stilp, Jason Bacon, Justin Wong, Braxton Mitchell, Joshua Lewis, Eric Boerwinkle, Ruth J.F. Loos, Michael Preuss, Kathleen Barnes, Nathan Pankratz, Myriam Fornage, Susan Redline, Bruce M. Psaty, Joshua C. Bis, Edwin Silverman, Michael Cho, Jeong Yun, Vasan Ramachandran, […]


Continue.. Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing

Quick-Look Pipeline Light Curves for 5.7 Million Stars Observed Over the Second Year of TESS’ First Extended Mission

Kavli Affiliate: Michael Fausnaugh | First 5 Authors: Michelle Kunimoto, Evan Tey, Willie Fong, Katharine Hesse, Avi Shporer | Summary: We present High-Level Science Products (HLSPs) containing light curves from MIT’s Quick-Look Pipeline (QLP) from the second year of TESS’ first Extended Mission (Sectors 40 – 55; 2021 July – 2022 September). In total, 12.2 […]


Continue.. Quick-Look Pipeline Light Curves for 5.7 Million Stars Observed Over the Second Year of TESS’ First Extended Mission

The giant low surface brightness galaxy Malin 1: new constraints for its molecular gas mass from GBT/ARGUS observations

Kavli Affiliate: Sarah Church | First 5 Authors: Gaspar Galaz, David T. Frayer, Matias BlaƱa, J. Christopher Howk, Thomas Puzia | Summary: We report on results from GBT/ARGUS $^{12}$CO(1-0) observations for the giant low surface brightness galaxy Malin 1, which allow us to determine an upper limit for its CO mass, and hence its molecular […]


Continue.. The giant low surface brightness galaxy Malin 1: new constraints for its molecular gas mass from GBT/ARGUS observations

Single-Photon Signal Sideband Detection for High-Power Michelson Interferometers

Kavli Affiliate: Lee McCuller | First 5 Authors: Lee McCuller, , , , | Summary: The Michelson interferometer is a cornerstone of experimental physics. Its applications range from providing first impressions of wave interference in educational settings to probing spacetime at minuscule precision scales. Interferometer precision provides a unique view of the fundamental medium of […]


Continue.. Single-Photon Signal Sideband Detection for High-Power Michelson Interferometers

Entanglement Dynamics of the Non-Unitary Holographic Channel

Kavli Affiliate: Masahiro Nozaki | First 5 Authors: Kanato Goto, Masahiro Nozaki, Kotaro Tamaoka, Mao Tian Tan, | Summary: We study the dynamical properties of a strongly scrambling quantum circuit involving a projective measurement on a finite-sized region by studying the operator entanglement entropy and mutual information (OEE and BOMI) of the dual operator state […]


Continue.. Entanglement Dynamics of the Non-Unitary Holographic Channel

Entanglement Dynamics of the Non-Unitary Holographic Channel

Kavli Affiliate: Masahiro Nozaki | First 5 Authors: Kanato Goto, Masahiro Nozaki, Kotaro Tamaoka, Mao Tian Tan, | Summary: We study the dynamical properties of a strongly scrambling quantum circuit involving a projective measurement on a finite-sized region by studying the operator entanglement entropy and mutual information (OEE and BOMI) of the dual operator state […]


Continue.. Entanglement Dynamics of the Non-Unitary Holographic Channel

Novel inhibitors against COVID-19 main protease suppressed viral infection

Kavli Affiliate: V. S. Ramachandran | Authors: Vijayan Ramachandran, Yanyun Liu, Qianying He, Andrew Tang, Patrick Ronaldson, Dominik Schenten and Rui Chang | Summary: Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19, can cause severe disease with high mortality rates, especially among older and vulnerable populations. Despite the recent success […]


Continue.. Novel inhibitors against COVID-19 main protease suppressed viral infection

FIXED: Frustratingly Easy Domain Generalization with Mixup

Kavli Affiliate: Xiang Zhang | First 5 Authors: Wang Lu, Jindong Wang, Han Yu, Lei Huang, Xiang Zhang | Summary: Domain generalization (DG) aims to learn a generalizable model from multiple training domains such that it can perform well on unseen target domains. A popular strategy is to augment training data to benefit generalization through […]


Continue.. FIXED: Frustratingly Easy Domain Generalization with Mixup