Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)

Posted by klaurent UCSD / Salk

Kavli Affiliate: John Reynolds | Authors: Courtney Glavis-Bloom, Casey R Vanderlip, Sammy Weiser Novak, Masaaki Kuwajima, Lyndsey Kirk, Uri Manor, Kristen M Harris and John H Reynolds | Summary: ABSTRACT Working memory relies critically on the dorsolateral prefrontal cortex (dlPFC). Morphology and function of the dlPFC, and corresponding working memory performance, are affected early in […]


Continue.. Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)

Generative network modeling reveals quantitative definitions of bilateral symmetry exhibited by a whole insect brain connectome

Posted by klaurent Hopkins

Kavli Affiliate: Carey Priebe, Joshua Vogelstein | Authors: Benjamin D. Pedigo, Mike Powell, Eric W. Bridgeford, Michael Winding, Carey E. Priebe and Joshua T. Vogelstein | Summary: Abstract Comparing connectomes can help explain how neural connectivity is related to genetics, disease, development, learning, and behavior. However, making statistical inferences about the significance and nature of […]


Continue.. Generative network modeling reveals quantitative definitions of bilateral symmetry exhibited by a whole insect brain connectome

Predicting pathways for old and new metabolites through clustering

Posted by Caltech

Kavli Affiliate: Nathan Lewis | First 5 Authors: Thiru Siddharth, Nathan Lewis, , , | Summary: The diverse metabolic pathways are fundamental to all living organisms, as they harvest energy, synthesize biomass components, produce molecules to interact with the microenvironment, and neutralize toxins. While discovery of new metabolites and pathways continues, the prediction of pathways […]


Continue.. Predicting pathways for old and new metabolites through clustering