Manipulation of neuronal activity in the entorhinal-hippocampal circuit affects intraneuronal amyloid-β levels

Kavli Affiliate: Menno Witter | Authors: Christiana Bjorkli, Nora Cecilie Ebbesen, Joshua B Julian, Menno P Witter, Axel Sandvig and Ioanna Sandvig | Summary: One of the neuropathological hallmarks of Alzheimer’s disease (AD) is the accumulation of amyloid-β (Aβ) plaques, which is preceded by intraneuronal build-up of toxic, aggregated Aβ during disease progression. Aβ plaques […]


Continue.. Manipulation of neuronal activity in the entorhinal-hippocampal circuit affects intraneuronal amyloid-β levels

Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

Kavli Affiliate: Gabriel Silva | Authors: Bruna M. Silva, Flavio Protasio Veras, Giovanni Gomes, Seppe Cambier, Gabriel Silva, Andreza Quadros, Diego Caetite, Daniele Nascimento, Camila Silva, Juliana Silva, Samara Damasceno, Ayda Schneider, Fabio Beretta, Sabrina Batah, Icaro Castro, Isadora Paiva, Tamara Rodrigues, Ana C G Salina, Ronaldo Martins, Guilherme Cebinelli, Naira Bibo, Daniel Jorge, Helder […]


Continue.. Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

Stochastic Variational Methods in Generalized Hidden Semi-Markov Models to Characterize Functionality in Random Heteropolymers

Kavli Affiliate: Ting Xu | First 5 Authors: Yun Zhou, Boying Gong, Tao Jiang, Ting Xu, Haiyan Huang | Summary: Recent years have seen substantial advances in the development of biofunctional materials using synthetic polymers. The growing problem of elusive sequence-functionality relations for most biomaterials has driven researchers to seek more effective tools and analysis […]


Continue.. Stochastic Variational Methods in Generalized Hidden Semi-Markov Models to Characterize Functionality in Random Heteropolymers

Dynamical Evolution of Brightest Cluster Galaxies and Their Host Clusters: Insights from IllustrisTNG

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Jubee Sohn, Margaret J. Geller, Mark Vogelsberger, Josh Borrow, | Summary: We explore the redshift evolution of the dynamical properties of massive clusters and their brightest cluster galaxies (BCGs) at $z < 2$ based on the IllustrisTNG-300 simulation. We select 270 massive clusters with $M_{200} < 10^{14}~{rm […]


Continue.. Dynamical Evolution of Brightest Cluster Galaxies and Their Host Clusters: Insights from IllustrisTNG

Black Hole and de Sitter Microstructures from a Semiclassical Perspective

Kavli Affiliate: Yasunori Nomura | First 5 Authors: Chitraang Murdia, Yasunori Nomura, Kyle Ritchie, , | Summary: We describe two different, but equivalent semiclassical views of black hole physics in which the equivalence principle and unitarity are both accommodated. In one, unitarity is built-in, while the black hole interior emerges only effectively as a collective […]


Continue.. Black Hole and de Sitter Microstructures from a Semiclassical Perspective

Black Hole and de Sitter Microstructures from a Semiclassical Perspective

Kavli Affiliate: Yasunori Nomura | First 5 Authors: Chitraang Murdia, Yasunori Nomura, Kyle Ritchie, , | Summary: We describe two different, but equivalent semiclassical views of black hole physics in which the equivalence principle and unitarity are both accommodated. In one, unitarity is built-in, while the black hole interior emerges only effectively as a collective […]


Continue.. Black Hole and de Sitter Microstructures from a Semiclassical Perspective

Black Hole and de Sitter Microstructures from a Semiclassical Perspective

Kavli Affiliate: Yasunori Nomura | First 5 Authors: Chitraang Murdia, Yasunori Nomura, Kyle Ritchie, , | Summary: We describe two different, but equivalent semiclassical views of black hole physics in which the equivalence principle and unitarity are both accommodated. In one, unitarity is built-in, while the black hole interior emerges only effectively as a collective […]


Continue.. Black Hole and de Sitter Microstructures from a Semiclassical Perspective

Population properties and multimessenger prospects of neutron star-black hole mergers following GWTC-3

Kavli Affiliate: Salvatore Vitale | First 5 Authors: Sylvia Biscoveanu, Philippe Landry, Salvatore Vitale, , | Summary: Neutron star-black hole (NSBH) mergers detected in gravitational-waves have the potential to shed light on supernova physics, the dense matter equation of state, and the astrophysical processes that power their potential electromagnetic counterparts. We use the population of […]


Continue.. Population properties and multimessenger prospects of neutron star-black hole mergers following GWTC-3