Kavli Affiliate: Michael Brainard | Authors: Lucas Y Tian, Timothy L Warren and Michael S Brainard | Summary: Complex behaviors depend on the coordinated activity of neural ensembles in interconnected brain areas. The behavioral function of such coordination, often measured as co-fluctuations in neural activity across areas, is poorly understood. One hypothesis is that rapidly […]
Kavli Affiliate: Nicholas Spitzer | Authors: Marta Pratelli, Arth Thaker, Huiquan Li, Swetha Godavarthi and Nicholas C. Spitzer | Summary: Decreased cognitive ability is a major consequence of exposure to drugs of abuse, but the underlying neuroplastic changes have been elusive. We show that both phencyclidine and methamphetamine cause a population of prelimbic pyramidal neurons […]
Kavli Affiliate: Fred Gage | Authors: Madison Wilson, Martin Thunemann, Xin Liu, Yichen Lu, Francesca Puppo, Jason Adams, Jeong-Hoon Kim, Donald Pizzo, Srdjan Djurovic, Ole Andreassen, Abed Mansour, Fred H. Gage, Alysson R Muotri, Anna Devor and Duygu Kuzum | Summary: Human cortical organoids, three-dimensional neuronal cell cultures derived from human induced pluripotent stem cells, […]
Kavli Affiliate: Patrick Kanold | Authors: Binghan Xue, Joseph P-Y Kao and Patrick O Kanold | Summary: A common impairment in aging is age-related hearing loss (presbycusis), which manifests as impaired spectrotemporal processing. Aging is accompanied by alteration in normal inhibitory (GABA) neurotransmission and changes in excitatory (NMDA and AMPA) synapses in the auditory cortex […]
Kavli Affiliate: Alex Zettl | First 5 Authors: Philipp M Pelz, Sinead Griffin, Scott Stonemeyer, Derek Popple, Hannah Devyldere | Summary: Transmission electron microscopy (TEM) is a potent technique for the determination of three-dimensional atomic scale structure of samples in structural biology and materials science. In structural biology, three-dimensional structures of proteins are routinely determined […]
Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Luis Enrique Pérez-Montaño, Vicente Rodriguez-Gomez, Bernardo Cervantes Sodi, Qirong Zhu, Annalisa Pillepich | Summary: We explore the nature of low surface brightness galaxies (LSBGs) in the hydrodynamic cosmological simulation TNG100 of the IllustrisTNG project, selecting a sample of LSBGs ($r$-band effective surface brightness $mu_r > 22.0$ mag […]
Kavli Affiliate: Ke Wang | First 5 Authors: Jian-Wen Zhou, Tie Liu, Neal J. Evans II, Guido Garay, Paul F. Goldsmith | Summary: We investigate the presence of hub-filament systems in a large sample of 146 active proto-clusters, using H$^{13}$CO$^{+}$ J=1-0 molecular line data obtained from the ATOMS survey. We find that filaments are ubiquitous […]
Kavli Affiliate: Xiang Zhang | First 5 Authors: Xiang Zhang, Ziyuan Zhao, Theodoros Tsiligkaridis, Marinka Zitnik, | Summary: Pre-training on time series poses a unique challenge due to the potential mismatch between pre-training and target domains, such as shifts in temporal dynamics, fast-evolving trends, and long-range and short cyclic effects, which can lead to poor […]
Kavli Affiliate: Xiang Zhang | First 5 Authors: Xiang Zhang, Ziyuan Zhao, Theodoros Tsiligkaridis, Marinka Zitnik, | Summary: Pre-training on time series poses a unique challenge due to the potential mismatch between pre-training and target domains, such as shifts in temporal dynamics, fast-evolving trends, and long-range and short cyclic effects, which can lead to poor […]
Kavli Affiliate: Anna Frebel | First 5 Authors: Mohammad K. Mardini, Anna Frebel, Anirudh Chiti, Yohai Meiron, Kaley V. Brauer | Summary: We have developed a chemo-dynamical approach to assign 36,010 metal-poor SkyMapper stars to various Galactic stellar populations. Using two independent techniques (velocity and action space behavior), $Gaia$ EDR3 astrometry, and photometric metallicities, we […]