Sampling with replacement vs Poisson sampling: a comparative study in optimal subsampling

Kavli Affiliate: Jing Wang | First 5 Authors: Jing Wang, Jiahui Zou, HaiYing Wang, , | Summary: Faced with massive data, subsampling is a commonly used technique to improve computational efficiency, and using nonuniform subsampling probabilities is an effective approach to improve estimation efficiency. For computational efficiency, subsampling is often implemented with replacement or through […]


Continue.. Sampling with replacement vs Poisson sampling: a comparative study in optimal subsampling

The Physics potential of the CEPC. Prepared for the US Snowmass Community Planning Exercise (Snowmass 2021)

Kavli Affiliate: Jia Liu | First 5 Authors: Huajie Cheng, Wen Han Chiu, Yaquan Fang, Yu Gao, Jiayin Gu | Summary: The Circular Electron Positron Collider (CEPC) is a large-scale collider facility that can serve as a factory of the Higgs, Z, and W bosons and is upgradable to run at the ttbar threshold. This […]


Continue.. The Physics potential of the CEPC. Prepared for the US Snowmass Community Planning Exercise (Snowmass 2021)

The Physics potential of the CEPC. Prepared for the US Snowmass Community Planning Exercise (Snowmass 2021)

Kavli Affiliate: Jia Liu | First 5 Authors: Huajie Cheng, Wen Han Chiu, Yaquan Fang, Yu Gao, Jiayin Gu | Summary: The Circular Electron Positron Collider (CEPC) is a large-scale collider facility that can serve as a factory of the Higgs, Z, and W bosons and is upgradable to run at the ttbar threshold. This […]


Continue.. The Physics potential of the CEPC. Prepared for the US Snowmass Community Planning Exercise (Snowmass 2021)

Avoiding a Cluster Catastrophe: Retention Efficiency and the Binary Black Hole Mass Spectrum

Kavli Affiliate: Daniel E. Holz | First 5 Authors: Michael Zevin, Daniel E. Holz, , , | Summary: The population of binary black hole mergers identified through gravitational waves has uncovered unexpected features in the intrinsic properties of black holes in the Universe. One particularly surprising and exciting result is the possible existence of black […]


Continue.. Avoiding a Cluster Catastrophe: Retention Efficiency and the Binary Black Hole Mass Spectrum

Avoiding a Cluster Catastrophe: Retention Efficiency and the Binary Black Hole Mass Spectrum

Kavli Affiliate: Daniel E. Holz | First 5 Authors: Michael Zevin, Daniel E. Holz, , , | Summary: The population of binary black hole mergers identified through gravitational waves has uncovered unexpected features in the intrinsic properties of black holes in the Universe. One particularly surprising and exciting result is the possible existence of black […]


Continue.. Avoiding a Cluster Catastrophe: Retention Efficiency and the Binary Black Hole Mass Spectrum

Distances to Local Group Galaxies via Population II, Stellar Distance Indicators I: The Sculptor Dwarf Spheroidal

Kavli Affiliate: Wendy L. Freedman | First 5 Authors: Quang H. Tran, Taylor J. Hoyt, Wendy L. Freedman, Barry F. Madore, Elias K. Oakes | Summary: We determine the distance to the Sculptor Dwarf Spheroidal via three Population II stellar distance indicators: (a) the Tip of the Red Giant Branch (TRGB), (b) RR Lyrae variables […]


Continue.. Distances to Local Group Galaxies via Population II, Stellar Distance Indicators I: The Sculptor Dwarf Spheroidal

Resolving information loss paradox with Euclidean path integral

Kavli Affiliate: Misao Sasaki | First 5 Authors: Pisin Chen, Misao Sasaki, Dong-han Yeom, Junggi Yoon, | Summary: The information loss paradox remains unresolved ever since Hawking’s seminal discovery of black hole evaporation. In this essay, we revisit the entanglement entropy via Euclidean path integral (EPI) and allow for the branching of semi-classical histories during […]


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Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death during Mammary Gland Involution

Kavli Affiliate: Shawn Ferguson | Authors: Jaekwang Jeong, Jongwon Lee, Gabriel Talaia, Wonnam Kim, Junho Song, Kwangmin Yoo, David G. Gonzalez, Diana Athonvarangkul, Jaehun Shin, Pamela Dann, Ann M Haberman, Lark Kyun Kim, Shawn M. Ferguson, Jungmin Choi and John Wysolmerski | Summary: Involution of the mammary gland after lactation is a dramatic example of […]


Continue.. Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death during Mammary Gland Involution

Serine Racemase is a Cysteine Racemase and Physiologic Down Regulator of Insulin Promoter Methylation

Kavli Affiliate: Solomon Snyder | Authors: Robin Roychaudhuri, Moataz M Gadalla, Lauren Albacarys, Timothy West, Harry Saavedra, Leon Mario Amzel and Solomon H. Snyder | Summary: Endogenous D-stereoisomers are being recognized as functionally important molecules in mammals. Here we report the first identification of endogenous D-cysteine in mammalian pancreas. Serine Racemase (SR) is the biosynthetic […]


Continue.. Serine Racemase is a Cysteine Racemase and Physiologic Down Regulator of Insulin Promoter Methylation

Clonally selected lines after CRISPR/Cas editing are not isogenic

Kavli Affiliate: Robert Edwards | Authors: Michael J. Roach, Sarah Beecroft, Kathie Mihindukulasuriya, Leran Wang, Lais Farias Oliveira Lima, Elizabeth A. Dinsdale, Robert Edwards and Scott Allyn Handley | Summary: The CRISPR-Cas9 system has enabled researchers to precisely modify/edit the sequence of a genome. A typical editing experiment consists of two steps: (i) editing cultured […]


Continue.. Clonally selected lines after CRISPR/Cas editing are not isogenic