Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons

Kavli Affiliate: Jin Kang | Authors: McSweeney, Rafael Gabriel, Kang Jin, Zhiping P. Pang, Bruce Aronow and ChangHui Pak | Summary: Loss-of-function (LOF) mutations in CASK cause severe developmental phenotypes, including microcephaly with pontine and cerebellar hypoplasia, X-linked intellectual disability, and autism. Unraveling the pathogenesis of CASK-related disorders has been challenging due to limited human […]


Continue.. Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons

Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission

Kavli Affiliate: David Kleinfeld | Authors: Abhi Aggarwal, Rui Liu, Yang Chen, Amelia J Ralowicz, Samuel J Bergerson, Filip Tomaska, Timothy L Hanson, Jeremy P Hasseman, Daniel Reep, Getahun Tsegaye, Pantong Yao, Xiang Ji, Marinus Kloos, Deepika Walpita, Ronak Patel, Paul W Tilberg, Boaz Mohar, The GENIE Project Team, Loren L Looger, Jonathan S Marvin, […]


Continue.. Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission

The halo bispectrum as a sensitive probe of massive neutrinos and baryon physics

Kavli Affiliate: Jia Liu | First 5 Authors: Victoria Yankelevich, Ian G. McCarthy, Juliana Kwan, Sam G. Stafford, Jia Liu | Summary: The power spectrum has been a workhorse for cosmological studies of large-scale structure. However, the present-day matter distribution is highly non-Gaussian and significant cosmological information is also contained in higher-order correlation functions. Meanwhile, […]


Continue.. The halo bispectrum as a sensitive probe of massive neutrinos and baryon physics

Evidence for a spinon Kondo effect in cobalt atoms on single-layer 1T-TaSe$_2$

Kavli Affiliate: Feng Wang | First 5 Authors: Yi Chen, Wen-Yu He, Wei Ruan, Jinwoong Hwang, Shujie Tang | Summary: Quantum spin liquids (QSLs) are highly entangled, disordered magnetic states that arise in frustrated Mott insulators and host exotic fractional excitations such as spinons and chargons. Despite being charge insulators some QSLs are predicted to […]


Continue.. Evidence for a spinon Kondo effect in cobalt atoms on single-layer 1T-TaSe$_2$

On the robustness of the velocity anisotropy parameter in probing the stellar kinematics in Milky Way like galaxies: Take away from TNG50 simulation

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Razieh Emami, Lars Hernquist, Mark Vogelsberger, Xuejian Shen, Joshua S. Speagle | Summary: We analyze the velocity anisotropy of stars in real and energy space for a sample of Milky Way-like galaxies in the TNG50 simulation. We employ different selection criteria, including spatial, kinematic and metallicity cuts, […]


Continue.. On the robustness of the velocity anisotropy parameter in probing the stellar kinematics in Milky Way like galaxies: Take away from TNG50 simulation

Insulin/IGF Signaling Regulates Presynaptic Glutamate Release in Aversive Olfactory Learning

Kavli Affiliate: Cornelia Bargmann | Authors: Du Cheng, James Lee, Maximillian Brown, Margaret S. Ebert, Masahiro Tomioka, Yuichi Iino and Cornelia I Bargmann | Summary: Information flow through neural circuits is continuously modified by context-dependent learning. In the nematode Caenorhabditis elegans, pairing specific odors with food deprivation results in aversion to the odor. Here we […]


Continue.. Insulin/IGF Signaling Regulates Presynaptic Glutamate Release in Aversive Olfactory Learning