Kavli Affiliate: Yifan Cheng | Authors: William Randall Arnold, David Julius and Yifan Cheng | Summary: Transient Receptor Potential Vanilloid 1 (TRPV1) is a tetrameric cation channel expressed in primary afferent neurons, where it contributes to thermosensation and nociception. TRPV1 is a polymodal signal integrator that responds not only to heat, but also to inflammatory […]
Continue.. Allosteric regulation of TRPV1 by the inflammatory lipid, LPA