Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Flora Vaccarino | Authors: Lovelace J Luquette, Tim H.H. Coorens, Abhiram Natu, Milovan Suvakov, Ann Caplin, Mee Sook Jun, Alisa Mo, Joe Pelt, Lisa Anderson, Michele Berselli, Sravya Bhamidipati, Thomas Blanchard, Joseph Brew, Hye-Jung E. Chun, Hyunbin Chun, Mrunal K. […]
Kavli Affiliate: Richard Huganir | Authors: Laura Sichlinger, Molly Reilly, Sakshi Arora, Shuo Zhang, Nicolas Marotta, Kiara L. Rodriguez-Acevedo, Marisol Hooks, Kyle S. Czarnecki, Julia J. Winter, Elisa A. Waxman, Lea V. Dungan, Ingie Hong, Yoichi Araki, Richard Johnson, Richard L. Huganir, Giulia Pavani, Deborah L. French, Beverly L. Davidson, Benjamin L. Prosser and Elizabeth […]
Kavli Affiliate: Flora Vaccarino | Authors: Abhiram Natu, Mrunal K. Dehankar, Reenal Pattni, Milovan Suvakov, Dmitrii Olisov, Livia Tomasini, Yeongjun Jang, Yiling Huang, Eva Benito-Garragori, Patrick Hasenfeld, Jan Korbel, Alexander E. Urban, Alexej Abyzov and Flora M. Vaccarino | Summary: The role of somatic mutations in human development and disease is obscured by difficulties in […]
Kavli Affiliate: Stephen Strittmatter | Authors: Francesca Mandino, Taekyung Kang, Xilin Shen, Corey Horien, Xenophon Papademetris, Stephen M. Strittmatter and Evelyn MR Lake | Summary: Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthesia to […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Stephen Strittmatter | Authors: Mikhail A Kostylev, Carmen Butan, Graham P Carmen, Yangyi Liu, Pallavi Gopal and Stephen M Strittmatter | Summary: Alzheimer’s disease is triggered by amyloid-ß, with symptoms linked to synapse loss. Oligomeric amyloid-ß, rather than monomeric or […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Stephen Strittmatter | Authors: Ramakrishnan Kannan, Xingxing Wang, LaShae Nicholson, Nancy Z. Lin, Elisa M. Howard, Atrayee Basu, Ines Ingabire, Yuichi Sekine and Stephen M. Strittmatter | Summary: Adult CNS trauma frequently causes neuronal disconnection and persistent deficits due to […]
Kavli Affiliate: Elena Gracheva | Authors: Tingting Gu, Elena Gracheva, Michael Lee, Wilson Leung, Sophia Bieser, Alixandria Nielsen, Adam T. Smiley, Nhi N.T. Vuong, Matthias Walther, Gunter Reuter, Sarah C.R. Elgin and Andrew M Arsham | Summary: Eukaryotic genomes are packaged into chromatin, a regulatory nucleoprotein assembly. Establishment, maintenance, and interconversion of chromatin states is […]
Kavli Affiliate: Marina Picciotto | Authors: Alexa R. Soares, Caroline Fai, Yann S. Mineur and Marina R. Picciotto | Summary: implicated in major depressive disorder and hyperactive NE signaling associated with post-traumatic stress disorder, suggesting that adequate mood regulation requires optimal NE levels. The basolateral amygdala (BLA) is a hub for stress processing and receives […]
Kavli Affiliate: Stephen Strittmatter | Authors: LaShae Nicholson, Si Jie Tang, Tejaswini Karra, Habiba Abouletta and Stephen M. Strittmatter | Summary: Metabolic dysfunction contributes to the risk and progression of Alzheimer”s disease (AD) through insulin signaling, but the cellular mechanisms are not fully understood. In this study, we examined the effects of streptozotocin-induced insulin deficiency […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Michael J Higley | Authors: Andrew Moberly, Jessica A Cardin and Michael Higley | Summary: Neuromodulation by acetylcholine (ACh) plays a critical role in reshaping neural dynamics in the neocortex as a function of development, behavioral state, and learning 1–6. […]