Kavli Affiliate: Michael J Higley | Authors: Alex Wang, Katie A. Ferguson, Jyoti Gupta, Michael J. Higley and Jessica A. Cardin | Summary: GABAergic inhibition is critical to the proper development of neocortical circuits. However, GABAergic interneurons are highly diverse and the developmental roles of distinct inhibitory subpopulations remain largely unclear. Dendrite-targeting, somatostatin-expressing interneurons (SST-INs) […]

Kavli Affiliate: Flora Vaccarino | Authors: Yifan Wang, Liana Fasching, Feinan Wu, Anita Huttner, Sabina Berretta, Rosalinda Roberts, James F. Leckman, Alexej Abyzov and Flora M. Vaccarino | Summary: Tourette syndrome (TS) is a disorder of high-order integration of sensory, motor, and cognitive functions afflicting as many as 1 in 150 children and characterized by […]

Kavli Affiliate: Anirvan Nandy | Authors: Xize Xu, Mitchell P Morton, Nyomi Hudson, Anirvan Nandy and Monika P. Jadi | Summary: Our visual experience is a result of the concerted activity of neuronal ensembles in the sensory hierarchy. Yet how the spatial organization of objects influences neural activity in this hierarchy remains poorly understood. We […]

Kavli Affiliate: Anirvan Nandy | Authors: Olivia C Meisner, Nicholas A Fagan, Joel Greenwood, Weikang Shi, Monika Jadi, Anirvan S. Nandy and Steve W. C. Chang | Summary: In recent years, the field of neuroscience has increasingly recognized the importance of studying animal behaviors in naturalistic environments to gain deeper insights into ethologically relevant behavioral […]

Kavli Affiliate: Anirvan Nandy | Authors: Feng Xing, Alec Graham Sheffield, Monika P. Jadi, Steve W. C. Chang and Anirvan S. Nandy | Summary: Social communication relies on the ability to perceive and interpret the direction of others’ attention, which is commonly conveyed through head orientation and gaze direction in both humans and non-human primates. […]

Kavli Affiliate: Marina Picciotto | Authors: Paul Jongseo Lee, Alexa R Soares, Yu Sun, Caroline Fai, Marina Picciotto and Junjie U Guo | Summary: While previous studies suggest that many mRNAs contain more than one translation initiation site (TIS), the biological significance of most alternative TISs and their corresponding protein isoforms (proteoforms) remains undetermined. Here […]

Kavli Affiliate: Anirvan Nandy | Authors: Anirban Das, Alec G. Sheffield, Anirvan S. Nandy and Monika P. Jadi | Summary: Adaptive information processing, comprised of local computations and their efficient routing, is crucial for flexible brain function. Spatial attention is a quintessential example of this adaptive process. It is critical for recognizing and interacting with […]

Kavli Affiliate: Anirvan Nandy | Authors: Mitchell P. Morton, Sachira Denagamage, Nyomi V. Hudson and Anirvan S. Nandy | Summary: Crowding, the impaired ability to accurately recognize a target stimulus among distractors, is a major bottleneck in visual perception. The spatial configuration of distractors in relation to the target profoundly influences perceptual fidelity. Notably, when […]

Kavli Affiliate: Stephen Strittmatter | Authors: Francesca Mandino, Xilin Shen, Gabriel Desrosiers-Gregoire, David O’Connor, Bandhan Mukherjee, Ashley Owens, An Qu, John Onofrey, Xenophon Papademetris, Mallar Chakravarty, Stephen M. Strittmatter and Evelyn MR Lake | Summary: Amyloid accumulation in Alzheimer’s disease (AD) is associated with synaptic damage and altered connectivity in brain networks. While measures of […]