Kavli Affiliate: Pietro De Camilli | Authors: Hui Wang, Matthew Kazaleh, Rachel A. Gioscia-Ryan, Jessica Millar, Gerard Temprano-Sagrera, Sherri Wood, Fran Van Den Burgh, Muriel G Blin, Kathleen M Wragg, Adrain Luna, Robert Bruce Hawkins, Scott A Soleimanpour, Maria Sabater-Lleal, Chang Shu, Daniel A Beard, Gorav Ailawadi, Jane C Deng, Daniel R Goldstein and Morgan […]
Kavli Affiliate: Anirvan Nandy | Authors: Mary Kate P Joyce, Tsvetoslav G Ivanov, Fenna Krienen, Jude Mitchell, Shaojie Ma, Wataru Inoue, Anirvan P Nandy, Dibyadeep Datta, Alvaro Duque, Jon I Arellano, Rahul Gupta, Guillermo Gonzalez-Burgos, David A Lewis, Nenad Sestan, Steven A McCarroll, Julio C Martinez-Trujillo, Seán Froudist-Walsh and Amy FT Arnsten | Summary: Marmosets […]
Kavli Affiliate: Pietro De Camilli and Shawn Ferguson | Authors: Xinbo Wang, Peng Xu, Amanda Bentley-DeSousa, William Hancock-Cerutti, Shujun Cai, Benjamin T Johnson, Francesca Tonelli, Lin Shao, Gabriel Talaia, Dario R Alessi, Shawn M Ferguson and Pietro De Camilli | Summary: Based on genetic studies, lysosome dysfunction is thought to play a pathogenetic role in […]
Kavli Affiliate: Pietro De Camilli | Authors: Michael G Hanna, Hely O Rodriguez Cruz, Kenshiro Fujise, Yumei Wu, C Shan Xu, Song Pang, Li Zhuoning, Mara Monetti and Pietro De Camilli | Summary: Recent studies have identified a family of rod-shaped proteins thought to mediate lipid transfer at intracellular membrane contacts by a bridge-like mechanism. […]
Kavli Affiliate: Pietro De Camilli | Authors: Anbang Dai, Peng Xu, Chase Amos, Kenshiro Fujise, Yumei Wu, Han Yang, Julia N. Eisen, Andrés Guillén-Samander and Pietro De Camilli | Summary: BLTP2/KIAA0100, a bridge-like lipid transfer protein, was reported to localize at contacts of the endoplasmic reticulum (ER) with either the plasma membrane (PM) or recycling […]
Kavli Affiliate: Anirvan Nandy | Authors: Feng Xing, Alec Graham Sheffield, Monika P. Jadi, Steve W. C. Chang and Anirvan S. Nandy | Summary: Social communication relies on the ability to perceive and interpret the direction of others’ attention, and is commonly conveyed through head orientation and gaze direction in humans and nonhuman primates. However, […]
Kavli Affiliate: Sreeganga Chandra | Authors: D J Vidyadhara, David Backstrom, Risha Chakraborty, Jiapeng Ruan, Jae-Min Park, Pramod K. Mistry and Sreeganga S. Chandra | Summary: GBA mutations are major risk factors for Parkinson′s disease (PD) and Dementia with Lewy Bodies (DLB), two common α-synucleinopathies associated with cognitive impairment. Here, we investigated the role of […]
Kavli Affiliate: Anirvan Nandy, John Reynolds | Authors: Mitchell P Morton, Sachira Denagamage, Isabel J Blume, John H Reynolds, Monika P Jadi and Anirvan S Nandy | Summary: Identical stimuli can be perceived or go unnoticed across successive presentations, producing divergent behavioral outcomes despite similarities in sensory input. We sought to understand how fluctuations in […]
Kavli Affiliate: Shawn Ferguson | Authors: Amanda Bentley-DeSousa and Shawn Ferguson | Summary: Mutations that increase LRRK2 kinase activity have been linked to Parkinson’s disease and Crohn’s disease. LRRK2 is also activated by lysosome damage evoked by chemical and pathogenic stimuli. However, the endogenous cellular mechanisms that control LRRK2 kinase activity are not well understood. […]
Kavli Affiliate: Ellen J. Hoffman | Authors: Maya Wilde, Anahita Ghanbari, Tessa Mancienne, Ailís Moran, Rebecca E. Poulsen, Lena Constantin, Conrad Lee, Leandro Aluisio Scholz, Joshua Arnold, Wei Qin, Timothy J. Karle, Steven Petrou, Itia A. Favre-Bulle, Ellen J. Hoffman and Ethan K. Scott | Summary: IAuditory processing is widely understood to occur differently in […]