Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Alex Pollen | Authors: Matthew T. Schmitz, Jingwen W. Ding, Sara Nolbrant, Reed McMullen, Chang N. Kim, Bryan J. Pavlovic, Tomasz J. Nowakowski, Trygve E. Bakken, Chun Jimmie Ye and Alex Aaron Pollen | Summary: Diverse neurons and glia are […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Philip Starr | Authors: Jin-Xiao Zhang, Clay Smyth, Hanna Cattan-Hayat, Md Fahim Anjum, Yue Leng, Andrew D. Krystal, Philip A. Starr and Simon Little | Summary: Sleep disturbances have been shown to be intimately and bidirectionally related to disease progression […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Yifan Cheng | Authors: Marcell Zimanyi, Kaitlin R Hulce, Markus F Bohn, Jordan Norman, Peter J Rohweder, Yifan Cheng and Charles Craik | Summary: Human herpesviruses (HHVs) are widespread pathogens that cause severe disease. Their replication depends on the HHV […]
Kavli Affiliate: Edward Chang and Loren Frank | Authors: Yitzhak Norman, Loren M. Frank and Edward F. Chang | Summary: Fluent speech depends on precisely timed motor commands that coordinate rapid transitions between successive articulatory gestures. Using direct cortical recordings, we identified a prominent sensorimotor theta oscillation (6–10 Hz) that supports this coordination. During articulation, […]
Kavli Affiliate: Zachary Knight | Authors: Brooke C Jarvie, Anagh Ravi, Rhea Nanavati, Longhui Qui, Truong Ly, Jun Y Oh, Olivia K Barnhill and Zachary A Knight | Summary: Calcitonin Gene-Related Peptide (CGRP) neurons in the parabrachial nucleus are critical for sickness and malaise but have also been proposed to control non-aversive (rewarding) satiation. How […]
Kavli Affiliate: Xin Duan | Authors: Daniela Santamaria-Munoz, Raenier V. Reyes, Miranda R. Krueger, Andrea Garcia-Llorca, Brennan Marsh-Armstrong, Xin Duan, Yang Hu, Derek S. Welsbie, Nicholas Marsh-Armstrong, Elisenda Sanz, Albert Quintana, Sergi Simo and Anna La Torre | Summary: Mitochondrial dysfunction is a central hallmark of many optic neuropathies, yet the mechanisms linking intrinsic metabolic […]
Kavli Affiliate: Jeanne Paz | Authors: Frances S. Cho, John R. Huguenard and Jeanne T. Paz | Summary: Long described as an inhibitory “guardian of the gateway,” the thalamic reticular nucleus (TRN) shapes which thalamic signals reach the cortex during attention, arousal, and sensory processing. However, how the inhibitory wiring within TRN supports this flexible […]
Kavli Affiliate: Kristofer Bouchard | Authors: Pierre-Marie Garderes, Daniel E. Feldman and Kristofer E. Bouchard | Summary: Electrocorticography (ECoG) provides a high-spatiotemporal-resolution measure of cortical activity (cortical surface electrical potentials, CSEPs) in humans and animals. The CSEP high-gamma band (Hγ, 65–170 Hz) correlates with neuronal firing rates at the columnar spatial scale and is widely […]
Kavli Affiliate: Anna Molofsky | Authors: Caroline C Escoubas, Ekin Guney, Alex Tudoras Miravet, Nathan Magee, Ronald Phua, Davide Ruggero, Anna V Molofsky and William A Weiss | Summary: Multielectrode array (MEA) technology enables simultaneous recording of electrical signals from neuronal networks, producing complex datasets. Current analytical approaches typically examine a limited number of metrics […]
Kavli Affiliate: Alex Pollen | Authors: Jingwen W Ding, Chang N Kim, Marilyn R Steyert, Andrew T Yuan, David Shin, Dimitar Ivanov, Tomasz J. Nowakowski and Alex Aaron Pollen | Summary: Down syndrome (DS), caused by trisomy 21 (TS21), is the most common genetic cause of intellectual disability1,2. The neurological impacts of DS first manifest […]