Uncovering population contributions to the extracellular potential in the mouse visual system using Laminar Population Analysis

Kavli Affiliate: Anders Dale | Authors: Atle Eskeland Rimehaug, Anders M. Dale, Anton Arkhipov and Gaute T. Einevoll | Summary: The local field potential (LFP), the low-frequency part of the extracellular potential, reflects transmembrane currents in the vicinity of the recording electrode. Thought mainly to stem from currents caused by synaptic input, it provides information […]


Continue.. Uncovering population contributions to the extracellular potential in the mouse visual system using Laminar Population Analysis

Long-Term Potentiation Produces a Sustained Expansion of Synaptic Information Storage Capacity in Adult Rat Hippocampus

Kavli Affiliate: Terrence Sejnowski | Authors: Dana E Cobb-Lewis, Anne George, Shannon Hu, Katherine Packard, Mingyuan Song, Oliver Nguyen-Lopez, Emily Ikematsu Tesone, Jhanay Rowden, Julie Wang and Maya Opendak | Summary: Long-term potentiation (LTP) has become a standard model for investigating synaptic mechanisms of learning and memory. Increasingly, it is of interest to understand how […]


Continue.. Long-Term Potentiation Produces a Sustained Expansion of Synaptic Information Storage Capacity in Adult Rat Hippocampus

Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition

Kavli Affiliate: Elizabeth Hillman, Mark Ellisman and Darcy Peterka | Authors: Alexander R. Goldberg, Athanassios Dovas, Daniela Torres, Sohani Das Sharma, Angeliki Mela, Edward M. Merricks, Markel Olabarria, Leila Abrishami Shokoohm, Hanzhi T. Zhao, Corina Kotidis, Peter Calvaresi, Ashwin Viswanathan, Matei A. Banu, Aida Razavilar, Tejaswi D. Sudhakar, Ankita Saxena, Cole Chokran, Nelson Humala, Aayushi […]


Continue.. Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition

Long range projections of oxytocin neurons in the marmoset brain

Kavli Affiliate: Cory Miller | Arthur Lefevre, Jazlynn Meza and Cory Miller | Summary: The neurohormone oxytocin (OT) has become a major target for the development of novel therapeutic strategies to treat psychiatric disorders such as autism spectrum disorder because of its integral role in governing many facets of mammalian social behavior. Whereas extensive work […]


Continue.. Long range projections of oxytocin neurons in the marmoset brain

Transforming chemigenetic bimolecular fluorescence complementation systems into chemical dimerizers using chemistry

Kavli Affiliate: Timothy Brown | Pratik Kumar, Alina Gutu, Amelia Waring, Timothy A Brown, Luke D Lavis and Alison G. Tebo | Summary: Chemigenetic tags are versatile labels for fluorescence microscopy that combine some of the advantages of genetically encoded tags with small molecule fluorophores. The Fluorescence Activating and absorbance Shifting Tags (FASTs) bind a […]


Continue.. Transforming chemigenetic bimolecular fluorescence complementation systems into chemical dimerizers using chemistry

Acute Neuropixels recordings in the marmoset monkey

Kavli Affiliate: John Reynolds | Authors: Nicholas M Dotson, Zachary W Davis, Patrick Jendritza and John H Reynolds | Summary: High-density linear probes, like Neuropixels, provide an unprecedented opportunity to understand how neural populations within specific laminar compartments contribute to behavior. Marmoset monkeys, unlike macaque monkeys, have a lissencephalic (smooth) cortex that enables recording perpendicular […]


Continue.. Acute Neuropixels recordings in the marmoset monkey

Social isolation recruits amygdala-cortical circuitry to escalate alcohol drinking

Kavli Affiliate: Kay Tye | Authors: Reesha Patel, Makenzie Patarino, Kelly Kim, Rachelle Pamintuan, Felix Taschbach, Hao Li, Christopher Lee, Aniek van Hoek, Rogelio Castro, Christian Cazares, Ray Miranda, Caroline Jia, Jeremy Delahanty, Kanha Batra, Laurel Keyes, Avraham Libster, Romy W. Wichmann, Talmo Pereira, Marcus Benna and Kay M. Tye | Summary: How do social […]


Continue.. Social isolation recruits amygdala-cortical circuitry to escalate alcohol drinking

Host–pathogen–vector continuum in a changing landscape: Drivers of Bartonella prevalence and evidence of historic spillover in a multi–host community

Kavli Affiliate: V. S. Ramachandran | Authors: B.R. Ansil, Ashwin Viswanathan, Vivek Ramachandran, H.M. Yeshwanth, Avirup Sanyal and Uma Ramakrishnan | Summary: Small mammals and their ectoparasites present a unique system to investigate the eco-epidemiology of multi-host vector-borne pathogens and identify specific bacterial spillover determinants. We applied ecological and evolutionary analyses in a rainforest-human-use mosaic […]


Continue.. Host–pathogen–vector continuum in a changing landscape: Drivers of Bartonella prevalence and evidence of historic spillover in a multi–host community

Mapping energy landscapes of homopolymeric RNAs via simulated tempering and deep unsupervised learning

Kavli Affiliate: V. S. Ramachandran | Authors: Vysakh Ramachandran and Davit A Potoyan | Summary: Conformational dynamics plays crucial roles in RNA functions about sensing and responding to environmental signals. The liquid-liquid phase separation of RNAs and the formation of stress granules partly relies on RNA’s conformational plasticity and its ability to engage in multivalent […]


Continue.. Mapping energy landscapes of homopolymeric RNAs via simulated tempering and deep unsupervised learning

Substructure of the brain’s Cingulo-Opercular network

Kavli Affiliate: Deanna J. Greene | Authors: Carolina Badke D’Andrea, Timoth O Laumann, Dillan J Newbold, Steven M Nelson, Ashley N Nielsen, Roselyne Chauvin, Scott Marek, Deanna J. Greene, Nico U F Dosenbach and Evan M Gordon | Summary: HThe Cingulo-Opercular network (CON) is an executive network of the human brain that regulates actions. CON […]


Continue.. Substructure of the brain’s Cingulo-Opercular network