Kavli Affiliate: Timothy Brown | Authors: Kristen C Ruegg, Christen M Bossu, Reza Goljani Amirkhiz, Nikunj Goel, Erica Robertson, Timothy M Brown, Kathryn Bernier, Ben J Vernasco, Peri E Bolton, Erik R Funk, Scott A Taylor, Mevin B Hooten and Erica S Zavaleta | Summary: Accelerated warming at high elevations is having a disproportionate impact […]
Kavli Affiliate: Marcelo Mattar | Authors: Sreejan Kumar, Matthieu B Le Cauchois, Alexander Mathis, Lea Duncker, Jonathon R. Howlett and Marcelo G. Mattar | Summary: The dorsolateral striatum (DLS) supports diverse time-sensitive behaviors—action chunking, duration estimation, and motor timing—yet no single framework is able to explain all of these phenomena. Here, we propose that the […]
Kavli Affiliate: Massimo Scanziani | Authors: Ellery Jones and Massimo Scanziani | Summary: A long-standing hypothesis in sensory neuroscience suggests that the evolutionary expansion of cortex in mammals may contribute to sensory-dependent adaptation by acting on subcortical pathways that drive innate behavior. However, direct experimental evidence is lacking. Taking the visual system as a model, […]
Kavli Affiliate: Mark Ellisman | Authors: Zhaoqi Yan, Andrew S Mendiola, Kelli Lauderdale, Keun-Young Kim, Yu Yong, Kun Leng, Eric A Bushong, Renaud Schuck, Anke Meyer-Franke, Ayushi Agrawal, Michela Traglia, Natalie Gill, Reuben Thomas, Jonah N Keller, Nikolaos Karvelas, Miguel F Vasquez, Daniel C Ballard, Matthew Madany, Jeffrey Simms, Brandon Guo, Reshmi Tognatta, Maria del […]
Kavli Affiliate: Mark Ellisman | Authors: Kelli Lauderdale, Zhaoqi Yan, Andrew S. Mendiola, Yutong Zhang, Dakota Mallen, Pranav Nambiar, Erica Brady, Stephanie R. Miller, Rosa Meza Acevedo, Belinda Cabriga, Fred Jiang, Nick Kaliss, Kevin Shen, Jia Shin, Jessica Herbert, Keran Ma, Jae Kyu Ryu, Ayushi Agrawal, Renaud Schuck, Maria del Pilar S. Alzamora, Jorge Sanz-Ros, […]
Kavli Affiliate: Tatyana Sharpee | Authors: Mingchen Yao, Anoop Praturu and Tatyana Sharpee | Summary: The rapid expansion of biological and computational datasets demands scalable methods that support both visualization and quantitative interpretation. Hyperbolic embeddings are well suited to represent hierarchical structure, but existing approaches are limited by fixed curvature assumptions or poor scalability to […]
Kavli Affiliate: Terrence Sejnowski | Authors: Margot Wagner, Yusi Chen, Arjun Karuvally, Mia Cameron and Terrence J Sejnowski | Summary: The hippocampus must balance stable memory representations with internally generated sequential dynamics underlying replay and prediction. How hippocampal circuitry achieves both remains unclear. Here, we show that recurrent neural networks trained on prediction tasks converge […]
Kavli Affiliate: John Reynolds | Authors: Emily S King, Liz Jaeschke-Angi, Hakuei Fujiyama, Wickliffe Abraham, Jennifer Rodger, John N Reynolds, Darren Clarke, Jamie L Beros and Alexander Tang | Summary: Repetitive transcranial magnetic stimulation (rTMS) is used widely in neuroscience to study and alter neural plasticity. The cellular mechanisms underlying the effect of rTMS on […]
Kavli Affiliate: Robert E. Clark | Authors: Robert Clark, Louis G. Smith, Matthew P. Leighton, Ryan J. Szukalo, Syma Khalid, Pablo G. Debenedetti, Pilar Cossio, Miro A. Astore and Sonya M. Hanson | Summary: Single-particle cryogenic electron microscopy (cryo-EM) has enabled near-atomic resolution structure determination of diverse biomolecules. Because the high vacuum required for electron […]
Kavli Affiliate: Marcelo Mattar | Authors: Sixing Chen, Frederick Callaway, Sreejan Kumar, Shira M. Lupkin, Joni D. Wallis, Vincent B. McGinty, Erin L. Rich and Marcelo G. Mattar | Summary: Two hallmarks of biological computation are its flexibility and efficiency. These features are often attributed to cognitive control processes that balance external utility against computational […]