Kavli Affiliate: Terrence Sejnowski | Authors: Thomas M Bartol, Mariam Ordyan, Terrence J Sejnowski, Padmini Rangamani and Mary B Kennedy | Summary: Long-term potentiation (LTP) is a biochemical process in excitatory glutamatergic synapses in the Central Nervous System (CNS). It is initiated by a bout of synaptic activation that is strong enough to contribute to […]

Kavli Affiliate: Edward Callaway | Authors: Rachel M. Cassidy, Angel V. Macias, Willian N. Lagos, Chiamaka Ugorji and Edward M. Callaway | Summary: Corticocortical (CC) projections in the visual system facilitate the hierarchical processing of sensory information. In addition to direct CC connections, indirect cortico-thalamo-cortical (CTC) pathways through the pulvinar nucleus of the thalamus can […]

Kavli Affiliate: Yishi Jin | Authors: Erin M Ritchie, Siming Zhong, Qianyi Pu, Yunbo Li, Binhai Zheng and Yishi Jin | Summary: The conserved MAP3K12/Dual Leucine Zipper Kinase (DLK) plays versatile roles in neuronal development, axon injury and stress responses, and neurodegeneration, depending on cell-type and cellular contexts. Emerging evidence implicates abnormal DLK signaling in […]

Kavli Affiliate: Kay Tye | Authors: James R Howe, Chung-Lung Chan, Donghyung Lee, Marlon Blanquart, Haylie Romero, Abigail N Zadina, Mackenzie E Lemieux, Paula A Desplats, Kay M Tye and Cory M Root | Summary: Animals perform innate behaviors that are stereotyped responses to specific evolutionarily relevant stimuli in the absence of prior learning or […]

Kavli Affiliate: Nicola Allen | Authors: James Deng, Lara Labarta-Bajo, Ashley N Brandebura, Samuel B Kahn, Antonio F M Pinto, Jolene K Diedrich and Nicola J Allen | Summary: Fragile X syndrome (FXS) is a monogenic neurodevelopmental disorder with manifestations spanning molecular, neuroanatomical, and behavioral changes. Astrocytes contribute to FXS pathogenesis and show hundreds of […]

Kavli Affiliate: Tatyana Sharpee | Authors: Yuansheng Zhou, Thomas F O’Connell, Majid Ghaninia, Brian Smith, Elizabeth J Hong and Tatyana O Sharpee | Summary: Odors provide an important communication channel between plants and animals. Fruits, vital nutrient sources for animals, emit a complex array of monomolecular volatiles. Animals can use the structure of these mixtures […]

Kavli Affiliate: Douglas Nitz | Authors: Alexander B Johnson and Douglas A Nitz | Summary: Neurons of posterior parietal cortex were recorded as rats performed a working memory task within a network of intersecting paths. The specific routes utilized in task performance provided opportunity to contrast responses of posterior parietal cortex sub-populations to linear and […]

Kavli Affiliate: Wesley Thompson | Authors: Lin Li, Mohammadreza Bayat, Timothy Hayes, Wesley K. Thompson, Arianna Morgan Sandmark Gard and Anthony Steven Dick | Summary: This paper addresses the challenges of managing missing values within expansive longitudinal neuroimaging datasets, using the specific example of data derived from the Adolescent Brain and Cognitive Development ABCD study. […]

Kavli Affiliate: Mark H. Tuszynski; | Authors: Pabitra K Sahoo, Nick Hanovice, Patricia Ward, Manasi A Agrawal, Terika P Smith, HaoMin SiMa, Jennifer N Dulin, Lauren S Vaughn, Mark Tuszynski, Kristy Welshhans, Larry Benowitz, Arthur English, John D Houle and Jeffery L Twiss | Summary: Depletion or inhibition of core stress granule proteins, G3BP1 in […]

Kavli Affiliate: Mark Ellisman; | Authors: Aaron T Kuan, Sebastien Phan, Keun-Young Kim, Mason Mackey, Minsu Kim, Steven T Peltier, Mark Ellisman and Wei-Chung Allen Lee | Summary: We demonstrate limited-tilt, serial section electron tomography (ET), which can non-destructively map brain circuits over large 3D volumes and reveal high-resolution, supramolecular details within subvolumes of interest. […]