Strain variation identifies a neural substrate for behavioral evolution in Drosophila

Kavli Affiliate: Vanessa Ruta | Anna Ryba, Philipp Brand, Rory T. Coleman, Yarden Greenfeld, Yael N. Tsitohay, Florian Hollunder, Katharine Keller, Murtaza Hathiyari, Tianyi Wei, Paolo Emilio Barbano and Vanessa Ruta | Summary: Sexual selection acts on heritable differences within species, driving the parallel diversification of signal production in one sex and behavioral responses in […]


Continue.. Strain variation identifies a neural substrate for behavioral evolution in Drosophila

Artificial Intelligence-driven Whole-brain Cell Mapping with Highly Multiplexed In Situ Hybridization

Kavli Affiliate: Nathaniel Heintz | Authors: Tatsuya Murakami, Meng Xia, Yurie Maeda, Yuejia Yin, Paolo Emilio Barbano, Ziyi Lin, Tomoyuki Mano, Kazuki Tainaka, Sam Reiter and Nathaniel Heintz | Summary: Recent advances in three-dimensional single-cell-resolution imaging have begun to link organ-wide and cellular level research in development and disease research. Harnessing the power of whole-mount […]


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Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants

Kavli Affiliate: Daniel Kronauer | Giacomo Leon Glotzer, P. Daniel H. Pastor and Daniel J. C. Kronauer | Summary: Communication is crucial to social life, and in ants, it is mediated primarily through olfaction. Ants have more odorant receptor (OR) genes than any other group of insects, generated through tandem duplications that produce large genomic […]


Continue.. Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants

A predicted structural interactome reveals binding interference from intrinsically disordered regions

Kavli Affiliate: Li Zhao | Junhui Peng and Li Zhao | Summary: Proteins function through dynamic interactions with other proteins in cells, forming complex networks fundamental to cellular processes. While high-resolution and high-throughput methods have significantly advanced our understanding of how proteins interact with each other, the molecular details of many important protein-protein interactions are […]


Continue.. A predicted structural interactome reveals binding interference from intrinsically disordered regions

Neuromodulator control of energy reserves in dopaminergic neurons

Kavli Affiliate: Timothy A. Ryan | Camila Pulido, Matthew S. Gentry and Timothy A. Ryan | Summary: The brain is a metabolically vulnerable organ as neurons have both high resting metabolic rates and the need for local rapid conversion of carbon sources to ATP during activity. Midbrain dopamine neurons are thought to be particularly vulnerable […]


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Neuroanatomical Basis of Coma in Acute Ischemic Stroke

Kavli Affiliate: Michael W. Young | Zheng Zhang, Milo White, Jennifer A Kim, Victor M Torres-Lopez, Aya Khalaf, David Jin, Aaron D Boes, Brian L Edlow, Stephen W English, David Fischer, Joel Geerling, Saleem M Halablab, Maarten G Lansberg, Margy McCullough-Hicks, James F Meschia, Patrik L Michel, Paola Palazzo, Benjamin D Reasoner, Robert W Regenhardt, […]


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Genomic resources for comparative analyses of obligate avian brood parasitism

Kavli Affiliate: Erich Jarvis | Authors: Rachel A Carroll, Edward Stallknecht Ricemeyer, LaDeana W Hillier, Jeffrey M DaCosta, Ekaterina Osipova, Sara Smith, Gabriel Jamie, Juan Gabriel Martinez, Mercedes Molina-Morales, Tomas Marques-Bonet, Joseph D Manthey, Diana Haddad, Matthew J Fuxjager, Kathleen S Lynch, Jonathan M.D. Wood, Erich Jarvis, Patrick Masterson, Francoise Thibaud-Nissen, Mark Hauber, Claire N […]


Continue.. Genomic resources for comparative analyses of obligate avian brood parasitism

Spatial Transcriptomics Reveal Developmental Dynamics of the Human Cerebral Cortex and Striatum

Kavli Affiliate: Li Zhao | Authors: Yunjia Zhang, Youning Lin, Xunan Shen, Xue Xiao, Cai Song, Xiaobo Shi, Tao Zhou, Yanxin Li, Zihan Wu, Zhenkun Zhuang, Chunqiong Li, Meng Li, Feng Wen, Jianlin Liu, Lei Cao, Qiangqiang Zhang, Zhao-Lu Li, Songbo Zhang, Susu Qu, Yaqi Li, Jianhua Yao, Fubaoqian Huang, Xin Liu, Ziqing Deng, Longqi […]


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Reconstructing Waddington’s Landscape from Data

Kavli Affiliate: Eric D. Siggia | Authors: Dillon J. Cislo, M Joaquina Delás, James Briscoe and Eric D. Siggia | Summary: The development of a zygote into a functional organism requires that this single progenitor cell gives rise to numerous distinct cell types. Attempts to exhaustively tabulate the interactions within developmental signaling networks that coordinate […]


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Mosquito sex under lock and key

Kavli Affiliate: Leslie B. Vosshall | Authors: Leah Houri-Zeevi, Madison M. Walker, Jacopo Razzauti, Anurag Sharma, H. Amalia Pasolli and Leslie B. Vosshall | Summary: Female mosquitoes typically mate once in a lifetime, making this singular mating decision critically important for the female. Yet, mosquito mating has been historically viewed as male-guided, with the female […]


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