Kavli Affiliate: Priya Rajasethupathy | Authors: Josue M Regalado, Ariadna Corredera Asensio, Theresa Haunold, Andrew C Toader, Yan Ran Li, Lauren A Neal and Priya Rajasethupathy | Summary: Learning requires the ability to link actions to outcomes. How motivation facilitates learning is not well understood. We designed a behavioral task in which mice self-initiate trials […]
Kavli Affiliate: A. James Hudspeth | Authors: Ryohei Oya, Kwang Min Woo, Brian Fabella, Rodrigo Gogui Alonso and Albert James Hudspeth | Summary: In the receptor organs of the inner ear and lateral line, sensory hair cells detect mechanical stimuli such as sounds, accelerations, and water movements. In each instance a stimulus deflects the hair […]
Kavli Affiliate: Winrich Freiwald | Authors: Ben Deen, Gasi Husain and Winrich A Freiwald | Summary: How does the brain process the faces of familiar people? Neuropsychological studies have argued for an area of the temporal pole (TP) linking faces with person identities, but magnetic susceptibility artifacts in this region have hampered its study with […]
Kavli Affiliate: Leslie B. Vosshall | Authors: Takeshi Morita, Nia G Lyn, Ricarda K von Heynitz, Olivia V Goldman, Trevor R Sorrells, Matthew DeGennaro, Benjamin J Matthews, Leah Houri-Zeevi and Leslie B Vosshall | Summary: Sensory compensation is a process that allows individuals with a loss of one sense, for instance hearing or vision, to […]
Kavli Affiliate: Timothy A. Ryan & Pietro De Camilli | Authors: Talex Kokotos, Aldana Antoniazzi, Santiago Unda, Myung Soo Kokotos, Daehun Park, David Eliezer, Michael Kaplitt, Pietro De Camilli and Timothy Ryan | Summary: Phosphoglycerate kinase 1 (PGK1), the first ATP producing glycolytic enzyme, has emerged as a therapeutic target for Parkinson’s Disease (PD), since […]
Kavli Affiliate: Daniel Mucida | Authors: Gregory P. Donaldson, Gabriella L. Reis, Marwa Saad, Izabela Mamede, Guo Chen, Nicole L. DelGaudio, Dayu Zhang, Begum Aydin, Caroline E. Harrer, Tiago B.R. Castro, Sergei Grivennikov, Bernardo S. Reis, Beth M. Stadtmueller, Gabriel D. Victora and Daniel Mucida | Summary: Immunoglobulin A (IgA) is the most abundant antibody […]
Kavli Affiliate: Mary E. Hatten, C. David Allis | Authors: Lijuan Feng, Douglas Barrows, Liangwen Zhong, Kart Matlik, Elizabeth G. Porter, Annaelle M. Djomo, Iris Yau, Alexey A. Soshnev, Thomas S. Carroll, Duancheng Wen, Mary E. Hatten, Benjamin A. Garcia and C. David Allis | Summary: Chromatin is a crucial regulator of gene expression and […]
Kavli Affiliate: Charles M. Rice | Authors: Shira Weingarten-Gabbay, Matthew R Bauer, Alexandra C Stanton, Susan Klaeger, Eva K Verzani, Daniel Lopez, Karl R Clauser, Steven A Carr, Jennifer G Abelin, Charles M Rice and Pardis C Sabeti | Summary: Unveiling the complete proteome of viruses is crucial to our understanding of the viral life […]
Kavli Affiliate: Charles M. Rice | Authors: Kunihiro Uryu, Nadine Soplop, Timothy P Sheahan, Maria-Teresa Catanese, Chuong Huynh, John Pena, Nancy Boudreau, Irina Matei, Candia Kenific, Ayako Hashimoto, Ayuko Hoshino, Charles M Rice and David Lyden | Summary: Scanning electron microscopy (SEM) offers an unparalleled view of the membrane topography of mammalian cells by using […]
Kavli Affiliate: Winrich Freiwald | Authors: Farid Aboharb, Stephen Serene, Julia Sliwa and Winrich A Freiwald | Summary: In the primate brain the frontal lobes support complex functions, including social cognition. Understanding the functional organization of these regions requires an approach for rich functional characterization. Here we used a novel paradigm, the visual exploration of […]