Kavli Affiliate: Michael Brainard | Authors: Bradley M Colquitt, Kelly Li, Foad Green, Robert J Veline and Michael S Brainard | Summary: SUMMARY Sensory feedback is required for stable execution of learned motor skills, and its loss can severely disrupt motor performance. The neural mechanisms that mediate sensorimotor stability have been extensively studied at systems […]
Kavli Affiliate: Patrick Kanold | Authors: Ji Liu and Patrick O Kanold | Summary: SUMMARY Predictive coding theory postulates that the brain achieves perception by actively making predictions about the incoming sensory information and correcting them if errors signals arise. These signals are likely the most relevant when the individual is actively interacting with the […]
Kavli Affiliate: Timothy A. Ryan | Authors: Mukesh Kumar, Justin Knapp, Kallol Gupta and Timothy A Ryan | Summary: Recent advances have expanded the role of lipid droplets (LDs) beyond passive lipid storage, implicating their involvement in various metabolic processes across mammalian tissues. Neuronal LDs, long debated in existence, have been identified in several neural […]
Kavli Affiliate: Fred Gage | Authors: Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H. Gage and Shani Stern | Summary: Abstract Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease. Primary symptoms of PD arise with the loss of dopaminergic (DA) neurons in […]
Kavli Affiliate: Jeremiah Cohen | Authors: Zhixiao Su and Jeremiah Y. Cohen | Summary: Abstract The cerebral cortex generates flexible behavior by learning. Reinforcement learning is thought to be driven by error signals in midbrain dopamine neurons. However, they project more densely to basal ganglia than cortex, leaving open the possibility of another source of […]
Kavli Affiliate: Menno Witter, Jonathan Whitlock | Authors: Karoline Hovde, Ida V. Rautio, Andrea Marie Hegstad, Menno P. Witter and Jonathan R. Whitlock | Summary: Abstract The mammalian visual system can be broadly divided into two functional processing pathways: a dorsal stream supporting visually and spatially guided actions, and a ventral stream enabling object recognition. […]
Kavli Affiliate: Rene Hen | Authors: Sebnem N. Tuncdemir, Andres D. Grosmark, Hannah Chung, Victor M. Luna, Clay O. Lacefield, Attila Losonczy and Rene Hen | Summary: Abstract The hippocampal dentate gyrus (DG) exhibits a unique form of neural plasticity that results from continuous integration of adult born neurons, referred to as ‘adult neurogenesis’. Recent […]
Kavli Affiliate: Robert Hawkins | Authors: Wenchao Gu, Sijin Luozhong, Ketaki Londhe, Nadine Elkasri, Simian Cai, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Margaret Cruz, Yu-Wei Chang, Patrick McMullen, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Tara Sarmiento, Chris Schaffer, Nozomi Nishimura, Richard Cerione, Melissa Warden, Robert Langer and Shaoyi Jiang | Summary: Abstract Systemic […]
Kavli Affiliate: Thomas P. Sakmar | Authors: Ilana B. Kotliar, Emilie Ceraudo, Kevin Kemelmakher-Liben, Deena A. Oren, Emily Lorenzen, Tea Dodig-Crnković, Mizuho Horioka-Duplix, Thomas Huber, Jochen M. Schwenk and Thomas P. Sakmar | Summary: Abstract Cholestatic itch is a severe and debilitating symptom in liver diseases with limited treatment options. The class A G protein-coupled […]
Kavli Affiliate: Daniel Kronauer | Authors: Lindsey E. Lopes, Erik T. Frank, Zsolt Kárpáti, Thomas Schmitt and Daniel J.C. Kronauer | Summary: Abstract Ants communicate via an arsenal of different pheromones produced in a variety of exocrine glands. For example, ants release alarm pheromones in response to danger to alert their nestmates and to trigger […]