Kavli Affiliate: Thomas P. Sakmar | Authors: Leo Dahl, Ilana Kotliar, Annika Bendes, Tea Dodig-Crnkovic, Samuel Fromm, Arne Elofsson, Mathias Uhlen, Thomas P Sakmar and Jochen Schwenk | Summary: Abstract G protein-coupled receptors (GPCRs) control critical cellular signaling pathways. Therapeutic agents, such as antibodies (Abs), are being developed to modulate GPCR signaling pathways. However, validating […]
Kavli Affiliate: Jean Laurent Casanova | Authors: Yann Aquino, Aurélie Bisiaux, Zhi Li, Mary O’Neill, Javier Mendoza-Revilla, Sarah Hélène Merkling, Gaspard Kerner, Milena Hasan, Valentina Libri, Vincent Bondet, Nikaïa Smith, Camille de Cevins, Mickaël M Ménager, Francesca Luca, Roger Pique-Regi, Giovanna Barba-Spaeth, Stefano Pietropaoli, Olivier Schwartz, Geert Leroux-Roels, Cheuk-Kwong Lee, Kathy Leung, Joseph T.K. Wu, […]
Kavli Affiliate: V. S. Ramachandran | Authors: Jack Parsons, Clare Cocker, Alison East, Rachel Wheatley, Vinoy Ramachandran, Farnusch Kaschani, Markus Kaiser and Philip Poole | Summary: Abstract Primary attachment of rhizobia to host legume roots depends on pH and is the first physical interaction during nodulation. Genome-wide insertion sequencing, luminescence-based attachment assays and proteomic analysis […]
Kavli Affiliate: Ying Meng | Authors: Akiko FUJIWARA, Xian-Ying Meng, Yoichi Kamagata and Tsutomu TSUCHIDA | Summary: Abstract Many insects contain endosymbiotic bacteria within their bodies. In multiple endosymbiotic systems comprising two or more symbionts, each of the symbionts is generally localized in a different host cell or tissue. Bemisia tabaci （Sweet potato whitefly）possesses a […]
Kavli Affiliate: Tatyana Sharpee | Authors: Ryan J. Rowekamp and Tatyana Sharpee | Summary: Abstract Despite recent successes in machine vision, artificial recognition systems continue to be less robust than biological systems. The brittleness of artificial recognition system has been attributed to the linearity of the core operation that matches inputs to target patterns at […]
Kavli Affiliate: Eran Mukamel | Authors: Junhao Li, Manoj K Jaiswal, Jo-Fan Chien, Alexey Kozlenkov, Ping Zhou, Mahammad Gardashli, Luc J Pregent, Erica Engelberg-Cook, Dennis W Dickson, Veronique V Belzil, Eran A Mukamel and Stella Dracheva | Summary: Abstract Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), are strongly influenced by […]
Kavli Affiliate: Paul Greengard | Authors: Ran Zhang, Margarete Knudsen, Pedro Del Cioppo Vasques, Alicja Tadych, Patricia Rodriguez-Rodriguez, Paul Greengard, Jean-Pierre Roussarie, Ana Milosevic and Olga G. Troyanskaya | Summary: Abstract Astrocytes have been shown to play a central role in Alzheimer’s Disease (AD). However, the genes and biological pathways underlying disease manifestation are unknown, […]
Kavli Affiliate: Terrence Sejnowski | Authors: João Pedro Carvalho Moriera, Vinícius Rezende Carvalho, Eduardo Mazoni Andrade Marçal Mendes, Aria Fallah, Terrence J. Sejnowski, Claudia Lainscsek and Lindy B Comstock | Summary: Abstract Electroencephalography (EEG) holds promise for brain-computer interface (BCI) devices as a non-invasive measure of neural activity. With increased attention to EEG-based BCI systems, […]
Kavli Affiliate: Denis Wirtz | Authors: Ashleigh J. Crawford, Clara Gomez-Cruz, Gabriella C. Russo, Wilson Huang, Isha Bhorkar, Arrate Munoz-Barrutia, Denis Wirtz and Daniel Garcia-Gonzalez | Summary: Abstract Cell proliferation and invasion are two key drivers of tumor progression and are traditionally considered two independent cellular processes regulated by distinct pathways. Through in vitro and […]
Kavli Affiliate: Kristofer Bouchard | Authors: Jiali Lu, Sumithra Surendralal, Kristofer E Bouchard and Dezhe Z. Jin | Summary: Abstract Songs of the Bengalese finch consist of variable sequences of syllables. The sequences follow probabilistic rules, and can be statistically described by partially observable Markov models (POMMs), which consist of states and probabilistic transitions between […]