Neuroscience – Page 89 – Kavli Institute Pre-Print Publications

Hippocampal area CA2 controls seizure dynamics, interictal EEG abnormalities and social comorbidity in mouse models of temporal lobe epilepsy

Posted by klaurent January 19, 2023February 7, 2023Columbia

Kavli Affiliate: Steven Siegelbaum | Authors: Christos Panagiotis Lisgaras, Azahara Oliva, Sam Mckenzie, John LaFrancois, Steven A. Siegelbaum and Helen E. Scharman | Summary: Temporal lobe epilepsy (TLE) is characterized by spontaneous recurrent seizures, abnormal activity between seizures, and impaired behavior. CA2 pyramidal neurons (PNs) are potentially important because inhibiting them with a chemogenetic approach […]

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EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

Posted by klaurent January 18, 2023January 30, 2023UCSD / Salk

Kavli Affiliate: Jose Suarez Lopez | Authors: Sukanya Chakraborty, Aaqib M. Bhat, Insha Mushtaq, Haitao Luan, Achyuth Kalluchi, Sameer Mirza, Matthew D. Storck, Nagendra Chaturvedi, Jose Antonio Lopez-Guerreo, Antonio Llombart-Bosch, Isidro Machado, Jane L. Meza, Gargi Ghosal, Donald W. Coulter, Jordan M. Rowley, Vimla Band, Bhopal C. Mohapatra and Hamid Band | Summary: We previously […]

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Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels

Posted by klaurent January 17, 2023January 30, 2023UCSF

Kavli Affiliate: Michael Keiser | Authors: Daniel R. Wong, Shino D. Magaki, Harry V. Vinters, William H. Yong, Edwin S. Monuki, Christopher K. Williams, Alessandra C. Martini, Charles DeCarli, Chris Khacherian, John P. Graff, Brittany N. Dugger and Michael J. Keiser | Summary: Precise, scalable, and quantitative evaluation of whole slide images is crucial in […]

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Grapevine scion gene expression is driven by rootstock and environment interaction

Posted by klaurent January 15, 2023January 23, 2023UCSD / Salk

Kavli Affiliate: Angela Wu | Authors: Zachary N Harris, Julia E Pratt, Laszlo G Kovacs, Laura L Klein, Misha T Kwasniewski, Jason P Londo, Angela Wu and Allison J Miller | Summary: BACKGROUND Grafting is a horticultural practice used widely across woody perennial crop species to fuse together the root and shoot system of two […]

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The neural activity of auditory conscious perception

Posted by klaurent January 13, 2023January 30, 2023Yale

Kavli Affiliate: Hal Blumenfeld | Authors: Kate L. Christison-Lagay, Noah C. Freedman, Christopher Micek, Aya Khalaf, Sharif I. Kronemer, Mariana M. Gusso, Lauren Kim, Sarit Forman, Julia Ding, Mark Aksen, Ahmad Abdel-Aty, Hunki Kwon, Noah Markowitz, Erin Yeagle, Elizabeth Espinal, Jose Herrero, Stephan Bickel, James Young, Ashesh Mehta, Kun Wu, Jason Gerrard, Eyiyemisi Damisah, Dennis […]

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End Binding protein 1 promotes specific motor-cargo association in the cell body prior to axonal delivery of Dense Core Vesicles

Posted by klaurent January 12, 2023January 30, 2023Yale

Kavli Affiliate: Pietro DeCamilli, Kenneth Miller | Authors: Junhyun Park, Kenneth G. Miller, Pietro De Camilli and Shaul Yogev | Summary: Axonal transport is key to neuronal function. Efficient transport requires specific motor-cargo association in the soma, yet the mechanisms regulating this early step remain poorly understood. We found that EBP-1, the C. elegans ortholog […]

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Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

Posted by klaurent January 11, 2023January 23, 2023Hopkins

Kavli Affiliate: Jeremy Nathans | Authors: Jie Wang, Amir Rattner and Jeremy Nathans | Summary: Bacterial meningitis is a major cause of morbidity and mortality, especially among infants and the elderly. Here we study mice to assess the response of each of the major meningeal cell types to early postnatal E. coli infection using single […]

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Low Rate Hippocampal Delay Period Activity Encodes Behavioral Experience

Posted by klaurent January 9, 2023January 23, 2023UCSD / Salk

Kavli Affiliate: Jill Leutgeb | Authors: Markos Athanasiadis, Stefano Masserini, Li Yuan, Dustin Fetterhoff, Jill K Leutgeb, Stefan Leutgeb and Christian Leibold | Summary: Remembering what just happened is a crucial prerequisite to form long-term memories but also for establishing and maintaining working memory. So far there is no general agreement about cortical mechanisms that […]

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Drosophila integrates visual evidence and counterevidence in self motion estimation

Posted by klaurent January 5, 2023March 7, 2023Yale

Kavli Affiliate: Damon Clark | Authors:Ryosuke Tanaka, Baohua Zhou, Margarida Agrochao, Bara A. Badwan, Braedyn Au, Natalia C. B. Matos and Damon A. Clark | Summary: In selecting a behavior, animals should weigh sensory evidence both for and against their beliefs about the world. For instance, animals use optic flow to estimate and control their […]

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Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors

Posted by dbos January 4, 2023January 16, 2024Hopkins

Kavli Affiliate: Denis Wirtzr | Authors:Adrian C. Johnston, Gretchen M. Alicea, Cameron C. Lee, Payal V. Patel, Eban A. Hanna, Eduarda Vaz, Andre Forjaz, Zeqi Wan, Praful R. Nair, Yeongseo Lim, Tina Chen, Wenxuan Du, Dongjoo Kim, Tushar D. Nichakawade, Vito W. Rebecca, Challice L. Bonifant, Rong Fan, Ashley L. Kiemen, Pei-Hsun Wu and Denis […]

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