Neuroscience – Page 72 – Kavli Institute Pre-Print Publications

SELENOT regulates endoplasmic reticulum calcium flux via SERCA2 and maintains dopaminergic DAT to protect against attention deficit hyperactivity disorder in mice

Posted by dbos November 9, 2023November 20, 2023Rockefeller

Kavli Affiliate: Li Zhao | Authors: Qing Guo, Zhao-Feng Li, Dong-Yan Hu, Pei-Jun Li, Kai-Nian Wu, Hui-Hui Fan, Jie Deng, Hong-Mei Wu, Xiong Zhang and Jian-Hong Zhu | Summary: Attention deficit and hyperactivity disorder (ADHD) is a prevalent developmental disorder. SELENOT is an endoplasmic reticulum-resident selenocysteine-containing protein. We aimed to investigate the role of SELENOT […]

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The entropic heart: Tracking the psychedelic state via heart rate dynamics

Posted by dbos November 9, 2023November 20, 2023UCSF

Kavli Affiliate: Reza Abbasi Asl & Adam Gazzaley | Authors: Fernando E. Rosas, Pedro A.M. Mediano, Christopher Timmermann, Andrea I Luppi, Diego Candia-Rivera, Reza Abbasi-Asl, Adam Gazzaley, Morten L Kringelbach, Suresh Daniel Muthukumaraswamy, Daniel Bor, Sarah Garfinkel and Robin Carhart-Harris | Summary: A growing body of work shows that autonomic signals provide a privileged evidence-stream […]

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Contexts facilitate dynamic value encoding in the mesolimbic dopamine system

Posted by dbos November 5, 2023November 13, 2023Hopkins

Kavli Affiliate: Patricia Janak | Authors: Kurt Michael Fraser, Val L Collins, Amy R Wolff, David J Ottenheimer, Kaisa N Bornhoft, Fiona Pat, Bridget J Chen, Patricia H Janak and Benjamin T Saunders | Summary: Adaptive behavior in a dynamic environment often requires rapid revaluation of stimuli that deviates from well-learned associations. The divergence between […]

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Electric fields determine carbapenemase activity in class A β-lactamases

Posted by dbos Hopkins

Kavli Affiliate: Michael Beer | Authors: Hira Jabeen, Michael Beer, James Spencer, Marc W van der Kamp, H Adrian Bunzel and Adrian J Mulholland | Summary: MAntimicrobial resistance is a public health crisis. Limited understanding of the catalytic drivers in resistance-mediating enzymes such as β-lactamases hinders our ability to combat this crisis. Here, we dissect […]

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Male-male interactions shape mate selection in Drosophila

Posted by dbos November 5, 2023November 13, 2023Rockefeller

Kavli Affiliate: Vanessa Ruta | Authors: Tom Hindmarsh Sten, Rufei Li, Florian Hollunder, Shadé Eleazer and Vanessa Ruta | Summary: Males of many species have evolved behavioral traits to both attract females and repel rivals. Here, we explore mate selection in Drosophila from both the male and female perspective to shed light on how these […]

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Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Posted by klaurent November 5, 2023November 13, 2023Hopkins

Kavli Affiliate: Denis Wirtz | Authors: Jeanette A.I. Johnson, Genevieve L Stein-O’Brien, Max Booth, Randy Heiland, Furkan Kurtoglu, Daniel Bergman, Elmar Bucher, Atul Deshpande, Andre Forjaz, Michael Getz, Ines Godet, Melissa Lyman, John Metzcar, Jacob Mitchell, Andrew Raddatz, Heber L. Rocha, Jacobo Solorzano, Aneequa Sundus, Yafei Wang, Daniele M. Gilkes, Luciane T. Kagohara, Ashley L. […]

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Robust reprogramming of glia into neurons by inhibition of Notch signaling and NFI factors in adult mammalian retina.

Posted by dbos November 5, 2023November 13, 2023Hopkins

Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Trieu-Duc Vu, Isabella Palazzo, Ritvik Pulya, Yehna Kim, Seth Blackshaw and Thanh Hoang | Summary: Neurogenic competence is actively repressed in mature mammalian Muller glial cells, and previous studies have predicted that this is in part mediated by active Notch signaling. To determine whether global loss of […]

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Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation

Posted by dbos November 4, 2023November 13, 2023Hopkins

Kavli Affiliate: Jeremias Sulam | Authors: Helge J Zollner, Christopher B. Davies-Jenkins, Dunja B. Simicic, Assaf Tal, Jeremias Sulam and Georg Oeltzschner | Summary: Purpose: The interest in application and modeling of dynamic MRS has recently grown. Therefore, it is imperative to systematically investigate accuracy, precision, and uncertainty estimation of 2D modeling algorithms. 2D modeling […]

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Association cortical areas in the mouse contain a large population of fast-spiking GABAergic neurons that do not express parvalbumin

Posted by dbos November 2, 2023November 13, 2023NTNU

Kavli Affiliate: Menno Witter and Maximiliano Jose Nigro | Authors: Erik J Courcelles, Kasper Kjelsberg, Laura Convertino, Rajeevkumar Raveendran Nair, Menno P Witter and Maximiliano J Nigro | Summary: GABAergic neurons represent 10-15% of the neuronal population of the cortex but exert a powerful control over information flow in cortical circuits. The largest GABAergic class […]

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Pathological claustrum activity drives aberrant cognitive network processing in human chronic pain

Posted by dbos November 2, 2023November 13, 2023Hopkins

Kavli Affiliate: Martin Lindquist | Authors: Brent William Stewart, Michael L Keaser, Hwiyoung Lee, Sarah M Margerison, Matthew A Cormie, Massieh Moayedi, Martin Lindquist, Shuo Chen, Brian N. Mathur and David A Seminowicz | Summary: Aberrant cognitive network activity and cognitive deficits are established features of chronic pain. However, the nature of cognitive network alterations […]

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