Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components using a large adolescent sample

Posted by klaurent UCSD / Salk

Kavli Affiliate: Anders Dale | Authors: Diana M. Smith, Pravesh Parekh, Joseph Kennedy, Robert J. Loughnan, Oleksandr Frei, Thomas E. Nichols, Ole A. Andreassen, Terry L. Jernigan and Anders M. Dale | Summary: The relative contributions of genetic variation and experience in shaping the morphology of the adolescent brain are not fully understood. Using longitudinal […]


Continue.. Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components using a large adolescent sample

Phylogeny of neocortical-hippocampal projections provides insight in the nature of human memory

Posted by dbos NTNU

Kavli Affiliate: Menno Witter | Authors: Daniel Reznik, Piotr Majka, Marcello GP Rosa, Menno P Witter and Christian F Doeller; | Summary: Throughout mammalian evolution, the hippocampal region, unlike the neocortex, largely preserved its cytoarchitectural organization and its role in mnemonic functions. This contrast raises the possibility that the hippocampal region receives different types of […]


Continue.. Phylogeny of neocortical-hippocampal projections provides insight in the nature of human memory

An unbiased method to partition diverse neuronal responses into functional ensembles reveals interpretable population dynamics during innate social behavior

Posted by dbos UCSD / Salk

Kavli Affiliate: Kay Tye | Authors: Alexander Lin, Cyril Akafia, Olga Dal Monte, Siqi Fan, Nicholas Fagan, Philip Putnam, Kay M. Tye, Steve Chang, Demba Ba and AZA Stephen Allsop; | Summary: In neuroscience, understanding how single-neuron firing contributes to distributed neural ensembles is crucial. Traditional methods of analysis have been limited to descriptions of […]


Continue.. An unbiased method to partition diverse neuronal responses into functional ensembles reveals interpretable population dynamics during innate social behavior

Structure of the Flotillin Complex in a Native Membrane Environment

Posted by dbos Rockefeller

Kavli Affiliate: Roderick MacKinnon | Authors: Ziao Fu and Roderick MacKinnon; | Summary: In this study we used cryo-electron microscopy to determine the structures of the Flotillin protein complex, part of the Stomatin, Prohibitin, Flotillin, and HflK/C (SPFH) superfamily, from cell-derived vesicles without detergents. It forms a right-handed helical barrel consisting of 22 pairs of […]


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A mismatch between striatal cholinergic pauses and dopaminergic reward prediction errors

Posted by dbos UCSF

Kavli Affiliate: Joshua Berke | Authors: Mariana Duhne, Ali Mohebi, Kyoungjun Kim, Lilian Pelattini and Joshua D. Berke; | Summary: Movement, motivation and reward-related learning depend strongly on striatal dopamine and acetylcholine. These neuromodulators each regulate the other, and disturbances to their coordinated signals contribute to human disorders ranging from Parkinson’s Disease to depression and […]


Continue.. A mismatch between striatal cholinergic pauses and dopaminergic reward prediction errors

Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology

Posted by dbos UCSD / Salk

Kavli Affiliate: Yishi Jin | Authors: Seungmee Park, Nathaniel Noblett, Lauren Pitts, Antonio Colavita, Ann M Wehman, Yishi Jin and Andrew D Chishol/p> | Summary: Mature neurons maintain their distinctive morphology for extended periods in adult life. Compared to developmental neurite outgrowth, axon guidance, and target selection, relatively little is known of mechanisms that maintain […]


Continue.. Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology

RealtimeDecoder: A fast software module for online clusterless decoding

Posted by dbos UCSF

Kavli Affiliate: Loren Frank | Authors: Joshua P Chu, Michael E Coulter, Eric L. Denovellis, Trevor TK Nguyen, Daniel F Liu, Xinyi Deng, Uri T Eden, Caleb T Kemere and Loren M Frank | Summary: Decoding algorithms provide a powerful tool for understanding the firing patterns that underlie cognitive processes such as motor control, learning, […]


Continue.. RealtimeDecoder: A fast software module for online clusterless decoding

Direct observation of the neural computations underlying a single decision

Posted by klaurent Columbia

Kavli Affiliate: Michael Shadlen | Authors: Natalie A Steinemann, Gabriel M Stine, Eric M Trautmann, Ariel Zylberberg, Daniel M Wolpert and Michael N Shadlen | Summary: Neurobiological investigations of perceptual decision-making have furnished the first glimpse of a flexible cognitive process at the level of single neurons (Shadlen and Newsome, 1996; Shadlen and Kiani, 2013). […]


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Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals

Posted by dbos UCSF

Kavli Affiliate: Kira Poskanzer | Authors: Xuelong Mi, Alex Bo-Yuan Chen, Daniela Duarte, Erin Carey, Charlotte R. Taylor, Philipp N. Braaker, Mark Bright, Rafael G. Almeida, Jing-Xuan Lim, Virginia M. Rutten, Wei Zheng, Mengfan Wang, Michael E. Reitman, Yizhi Wang, Kira E. Poskanzer, David A. Lyons, Axel Nimmerjahn, Misha B. Ahrens and Guoqiang Yu | […]


Continue.. Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals