Single neurons and networks in the claustrum integrate input from widespread cortical sources

Kavli Affiliate: Clifford Kentros, Menno Witter | Authors: Andrew M Shelton, David K Oliver, Joachim S Grimstvedt, Ivan P Lazarte, Ishaan Kapoor, Jake A Swann, Caitlin A Ashcroft, Simon N Williams, Niall Conway, Amy Robinson, Clifford G Kentros, Menno P Witter, Simon JB Butt and Adam M Packer | Summary: The claustrum is highly interconnected […]


Continue.. Single neurons and networks in the claustrum integrate input from widespread cortical sources

Spatial and morphological organization of mitochondria across a connectome

Kavli Affiliate: Damon Clark | Authors: Garrett Sager, Fabian Cole Pallasdies, Robert Gowers, Snusha Ravikumar, Elizabeth Wu, Daniel Colon-Ramos, Susanne Schreiber and Damon A Clark | Summary: Summary: Neuronal function depends critically on the cell biological organization of mitochondria, which regulate calcium signals and produce energy, among other roles. However, little is known about how […]


Continue.. Spatial and morphological organization of mitochondria across a connectome

Intermittent Theta Burst Stimulation Drives Bi-Directional Changes in Excitability in Prefrontal Cortex

Kavli Affiliate: Jyoti Mishra and Dhakshin Ramanathan | Authors: Morteza Salimi, Milad Nazari, Jonathan Mishler, Jyoti Mishra and Dhakshin Ramanathan | Summary: Summary: Theta burst stimulation (TBS), an FDA-cleared treatment for depression, is hypothesized to modulate excitability in the prefrontal cortex, though this has not definitively been shown in vivo. We performed calcium imaging on […]


Continue.. Intermittent Theta Burst Stimulation Drives Bi-Directional Changes in Excitability in Prefrontal Cortex

A Real-time Multi-Subject Three Dimensional Pose Tracking System for Analyzing Social Behaviors of Non-human Primates

Kavli Affiliate: Xiaoqin Wang | Authors: Chaoqun Cheng, Zijian Huang, Ruiming Zhang, Guozheng Huang, Han Wang, Likai Tang and Xiaoqin Wang | Summary: Summary: The ability to track positions and poses (body parts) of multiple monkeys in a 3D space in real time is highly desired by non-human primate (NHP) researchers in behavioral and systems […]


Continue.. A Real-time Multi-Subject Three Dimensional Pose Tracking System for Analyzing Social Behaviors of Non-human Primates

Functional Regrowth of Norepinephrine Axons in the Adult Mouse Brain Following Injury

Kavli Affiliate: David Linden | Authors: Patrick R Cooke and David J Linden | Summary: Summary: It is widely believed that axons in the central nervous system of adult mammals do not regrow following injury. This failure is thought, at least in part, to underlie the limited recovery of function following injury to the brain […]


Continue.. Functional Regrowth of Norepinephrine Axons in the Adult Mouse Brain Following Injury

CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development

Kavli Affiliate: Jean Fan and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Summary: Definition of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Marker […]


Continue.. CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development

CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Kavli Affiliate: Donald Geman and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Accurate identification of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Such […]


Continue.. CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage

Kavli Affiliate: Jean Fan | Authors: Katy Boerner, Philip D Blood, Jonathan C Silverstein, Matthew Ruffalo, Sarah A Teichmann, Gloria Pryhuber, Ravi S Misra, Jeffrey M Purkerson, Jean Fan, John W Hickey, Gesmira Molla, Chuan Xu, Yun Zhang, Griffin M Weber, Yashvardhan Jain, Danial Qaurooni, Yongxin Kong, Andreas Bueckle and Bruce W Herr II | […]


Continue.. Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage

Spontaneous calcium transients in hair cell stereocilia

Kavli Affiliate: Dwight Bergles | Authors: Saman Hussain, Miloslav Sedlacek, Runjia Cui, Wendy Zhang-Hooks, Dwight E Bergles, Jung-Bum Shin, Katie Kindt and Bechara Kachar | Summary: The hair bundle of auditory and vestibular hair cells converts mechanical stimuli into electrical signals through mechanoelectrical transduction (MET). The MET apparatus is built around a tip link that […]


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Dynamic medial parietal and hippocampal deactivations under DMT relate to sympathetic output and altered sense of time, space, and the self

Kavli Affiliate: Adam Gazzaley | Authors: Lorenzo Pasquini, Alexander Simon, Courtney Gallen, Hannes Kettner, Leor Roseman, Adam Gazzaley, Robin Carhart-Harris and Christopher Timmermann | Summary: N,N-Dimethyltryptamine (DMT) is a serotonergic psychedelic, known to rapidly induce short-lasting alterations in conscious experience, characterized by a profound and immersive sense of physical transcendence alongside rich and vivid auditory […]


Continue.. Dynamic medial parietal and hippocampal deactivations under DMT relate to sympathetic output and altered sense of time, space, and the self