Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology

Kavli Affiliate: Yishi Jin | Authors: Seungmee Park, Nathaniel Noblett, Lauren Pitts, Antonio Colavita, Ann M Wehman, Yishi Jin and Andrew D Chishol/p> | Summary: Mature neurons maintain their distinctive morphology for extended periods in adult life. Compared to developmental neurite outgrowth, axon guidance, and target selection, relatively little is known of mechanisms that maintain […]


Continue.. Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology

RealtimeDecoder: A fast software module for online clusterless decoding

Kavli Affiliate: Loren Frank | Authors: Joshua P Chu, Michael E Coulter, Eric L. Denovellis, Trevor TK Nguyen, Daniel F Liu, Xinyi Deng, Uri T Eden, Caleb T Kemere and Loren M Frank | Summary: Decoding algorithms provide a powerful tool for understanding the firing patterns that underlie cognitive processes such as motor control, learning, […]


Continue.. RealtimeDecoder: A fast software module for online clusterless decoding

Direct observation of the neural computations underlying a single decision

Kavli Affiliate: Michael Shadlen | Authors: Natalie A Steinemann, Gabriel M Stine, Eric M Trautmann, Ariel Zylberberg, Daniel M Wolpert and Michael N Shadlen | Summary: Neurobiological investigations of perceptual decision-making have furnished the first glimpse of a flexible cognitive process at the level of single neurons (Shadlen and Newsome, 1996; Shadlen and Kiani, 2013). […]


Continue.. Direct observation of the neural computations underlying a single decision

Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals

Kavli Affiliate: Kira Poskanzer | Authors: Xuelong Mi, Alex Bo-Yuan Chen, Daniela Duarte, Erin Carey, Charlotte R. Taylor, Philipp N. Braaker, Mark Bright, Rafael G. Almeida, Jing-Xuan Lim, Virginia M. Rutten, Wei Zheng, Mengfan Wang, Michael E. Reitman, Yizhi Wang, Kira E. Poskanzer, David A. Lyons, Axel Nimmerjahn, Misha B. Ahrens and Guoqiang Yu | […]


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Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation

Kavli Affiliate: Keri Martinowich | Authors: Anthony Dial Ramnauth, Madhavi Tippani, Heena R. Divecha, Alexis R. Papariello, Ryan A Miller, Erik D Nelson, Elizabeth A. Pattie, Joel E. Kleinman, Kristen R. Maynard, Leonardo Collado-Torres, Thomas M. Hyde, Keri Martinowich, Stephanie C Hicks and Stephanie Cerceo Page | Summary: The dentate gyrus of the hippocampus is […]


Continue.. Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation

Modulation of aggression by social novelty recognition memory in the hippocampal CA2 region

Kavli Affiliate: Steven Siegelbaum | Authors: Andres Villegas and Steven A Siegelbaum | Summary: The dorsal CA2 subregion (dCA2) of the hippocampus exerts a critical role in social novelty recognition (SNR) memory and in the promotion of social aggression. Whether the social aggression and SNR memory functions of dCA2 are related or represent independent processes […]


Continue.. Modulation of aggression by social novelty recognition memory in the hippocampal CA2 region

Two routes to value-based decisions in Parkinsons disease: differentiating incremental reinforcement learning from episodic memory

Kavli Affiliate: Daphna Shohamy | Authors: Peter Jendrichovsky, Hey-Kyoung Lee and Patrick O Kanold | Summary: Patients with Parkinsons disease are impaired at incremental reward-based learning. It is typically assumed that this impairment reflects a loss of striatal dopamine. However, many open questions remain about the nature of reward-based learning deficits in Parkinsons. Recent studies […]


Continue.. Two routes to value-based decisions in Parkinsons disease: differentiating incremental reinforcement learning from episodic memory

Dark exposure reduces high-frequency hearing loss in C57BL/6J mice

Kavli Affiliate: Hey-Kyoung Lee and Patrick Kanold | Authors: Peter Jendrichovsky, Hey-Kyoung Lee and Patrick O Kanold | Summary: Plastic changes in the brain are primarily limited to early postnatal periods. Recovery of adult brain plasticity is critical for the effective development of therapies. A brief (1-2 week) duration of visual deprivation (dark exposure, DE) […]


Continue.. Dark exposure reduces high-frequency hearing loss in C57BL/6J mice

Coordination and persistence of aggressive visual communication in Siamese fighting fish

Kavli Affiliate: Liam Paninski | Authors: Claire P. Everett, Amy L. Norovich, Jessica E. Burke, Matthew R Whiteway, Pei-Yin Shih, Yuyang Zhu, Liam Paninski and Andres Bendesky | Summary: Animals coordinate their behavior with each other during both cooperative and agonistic social interactions. Such coordination often adopts the form of “turn taking”, in which the […]


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Distinct anatomical and functional corticospinal inputs innervate different spinal neuron types

Kavli Affiliate: Liam Paninski | Authors: Samaher Fageiry, Claire L Warriner, Jackson Loper, Liam Paninski, Thomas Reardon, Thomas M. Jessell, Rui M. Costa and Andrew Miri | Summary: The corticospinal tract exerts its influence on movement through spinal neurons, which can be divided into types that exhibit distinct functions. However, it remains unknown whether these […]


Continue.. Distinct anatomical and functional corticospinal inputs innervate different spinal neuron types