Kavli Affiliate: Dwight Bergles | Authors: Cody L. Call, Sarah A. Neely, Jason J. Early, Owen G. James, Lida Zoupi, Anna C. Williams, Siddharthan Chandran, David A. Lyons and Dwight E. Bergles | Summary: Myelin sheaths in the CNS are generated by the tips of oligodendrocyte processes, which wrap axons to accelerate action potential conduction, […]
Kavli Affiliates: Jingyi Guo, Claudia Battistin, Tuce Tombaz, Bartul Mimica, Jonathan Whitlock | Authors: Bartul Mimica, Tuçe Tombaz, Claudia Battistin, Jingyi Guo Fuglstad, Benjamin A. Dunn and Jonathan R. Whitlock | Summary: The Cortical population code is pervaded by activity patterns evoked by movement, but how such signals relate to the natural actions of unrestrained […]
Kavli Affiliate: Michael N Shadlen | Authors: NaYoung So and Michael N Shadlen | Summary: Neurons in the lateral intraparietal cortex (area LIP) represent the formation of a decision when it is linked to a specific action, such as an eye movement to a choice target. However, these neurons should be unable to represent a […]
Kavli Affiliate: Jin Kang | Authors: McSweeney, Rafael Gabriel, Kang Jin, Zhiping P. Pang, Bruce Aronow and ChangHui Pak | Summary: Loss-of-function (LOF) mutations in CASK cause severe developmental phenotypes, including microcephaly with pontine and cerebellar hypoplasia, X-linked intellectual disability, and autism. Unraveling the pathogenesis of CASK-related disorders has been challenging due to limited human […]
Kavli Affiliate: David Kleinfeld | Authors: Abhi Aggarwal, Rui Liu, Yang Chen, Amelia J Ralowicz, Samuel J Bergerson, Filip Tomaska, Timothy L Hanson, Jeremy P Hasseman, Daniel Reep, Getahun Tsegaye, Pantong Yao, Xiang Ji, Marinus Kloos, Deepika Walpita, Ronak Patel, Paul W Tilberg, Boaz Mohar, The GENIE Project Team, Loren L Looger, Jonathan S Marvin, […]
Kavli Affiliate: Cornelia Bargmann | Authors: Du Cheng, James Lee, Maximillian Brown, Margaret S. Ebert, Masahiro Tomioka, Yuichi Iino and Cornelia I Bargmann | Summary: Information flow through neural circuits is continuously modified by context-dependent learning. In the nematode Caenorhabditis elegans, pairing specific odors with food deprivation results in aversion to the odor. Here we […]
Kavli Affiliate: Samuel Pfaff | Authors: Remi Ronzano, Sophie Skarlatou, Bianca K Barriga, B. Anne Bannatyne, Gardave Singh Bhumbra, Joshua David Foster, Jeffrey Moore, Camille Lancelin, Amanda Pocratsky, Mustafa Gorkem Ozyurt, Calvin Chad Smith, Andrew J. Todd, David J. Maxwell, Andrew J. Murray, Samuel L Pfaff, Robert M. Brownstone, Niccolo’ Zampieri and Marco Beato | […]
Kavli Affiliate: Michael Shadlen | Authors: Naomi N Odean, Mehdi Sanayei and Michael N Shadlen | Summary: Abstract To form a perceptual decision the brain must acquire samples of evidence from the environment and incorporate them in computations that mediate choice behavior. While much is known about the neural circuits that process sensory information and […]
Kavli Affiliate: Marcelo Mattar | Authors: Flora Bouchacourt, Sina Tafazoli, Marcelo Gomes Mattar, Timothy J Buschman and Nathaniel Douglass Daw | Summary: Abstract To adapt to a changing world, we must be able to switch between rules already learned and, at other times, learn rules anew. Often we must do both at the same time, […]
Kavli Affiliate: David Rowitch | Authors: Tanay Ghosh, Rafael G Almeida, Chao Zhao, Abdelkrim Mannioui, Elodie Martin, Alex Fleet, Ginez Gonzalez M, David H Rowitch, Katherine Stott, Ian Adams, Bernard Zalc, Nick Goldman, David A Lyons and Robin JM Franklin | Summary: Abstract Myelin, the insulating sheath that surrounds neuronal axons, is produced by oligodendrocytes […]