Kavli Affiliate: Alex Kolodkin | Authors: Sriram Sudarsanam, Luis Guzman-Clavel, Nyle Dar, Jakub Ziak, Naseer Shahid, Xinyu O Jin and Alex L Kolodkin | Summary: Cortical connectivity is contingent on ordered emergence of neuron subtypes followed by the formation of subtype-specific axon projections. Intracortical circuits, including long-range callosal projections, are crucial for information processing, but […]

Kavli Affiliate: John Rubenstein and Vikaas Sohal | Authors: Marc Turner, Sarah Robinson-Schwartz, Siavash Fazel Darbandi, John L.R. Rubenstein and Vikaas Singh Sohal | Summary: Disruptions in many genes linked to autism spectrum disorder (ASD) affect synaptic function and socioemotional behaviors in mice. However, exactly how synaptic dysfunction alters neural activity patterns underlying behavior remains […]

Kavli Affiliate: Michael Miller | Authors: Zifan Xie, Yong-Su Jin and Michael J Miller | Summary: Lacticaseibacillus rhamnosus GG (LGG) is one of the most studied probiotic strains and is widely used in both food and therapeutic industries. With its safe and health-beneficial properties, LGG is an ideal candidate for genome modification to enhance its […]

Kavli Affiliate: Richard Axel | Authors: Andrew Jacob Pixley Fink, Samuel Muscinelli, Shuqi Wang, Marcus I Hogan, Daniel Fine English, Richard Axel, Ashok Litwin-Kumar and Carl E. Schoonover | Summary: Non-peptide ligands (NPLs), including lipids, amino acids, carbohydrates, and non-peptide neurotransmitters and hormones, play a critical role in ligand-receptor-mediated cell-cell communication, driving diverse physiological and […]

Kavli Affiliate: Richard Huganir | Authors: Julia Brill, Blaise Clarke, Ingie Hong and Richard L. Huganir | Summary: SYNGAP1 is a key Ras-GAP protein enriched at excitatory synapses, with mutations causing intellectual disability and epilepsy in humans. Recent studies have revealed that in addition to its role as a negative regulator of G-protein signaling through […]

Kavli Affiliate: David Linden | Authors: Ruben Andreas Bressler, Assunta Ciarlo, Sophie Raible, Giancarlo Valente, Michael Lührs, Ralph Tier, David E Linden and Rainer Goebel | Summary: Multi-voxel pattern analysis (MVPA) is a powerful technique to decode brain states from functional magnetic resonance imaging (fMRI) activity patterns. In neurofeedback (NF) applications, it has been used […]

Kavli Affiliate: Brian Caffo | Authors: Patrick Sadil, Konstantinos Arfanakis, Enamul Hoque Bhuiyan, Brian Caffo, Vince D Calhoun, Daniel J Clauw, Mark C DeLano, James C Ford, Ramtalik Gattu, Xiaodong Guo, Richard E Harris, Eric Ichesco, Micah A Johnson, Heejung Jung, Ari B Kahn, Chelsea M Kaplan, Nondas Leloudas, Martin A Lindquist, Qingfei Luo, Todd […]

Kavli Affiliate: Vikram Chib | Authors: Michael Dryzer and Vikram S. Chib | Summary: Fatigue is a state of exhaustion that influences our willingness to engage in effortful tasks. While both physical and cognitive exertion can cause fatigue, there is a limited understanding of how fatigue in one exertion domain (e.g., cognitive) affects decisions to […]

Kavli Affiliate: Keri Martinowich | Authors: Erik D. Nelson, Madhavi Tippani, Anthony D. Ramnauth, Heena R. Divecha, Ryan A. Miller, Nicholas J. Eagles, Elizabeth A. Pattie, Sang Ho Kwon, Svitlana V. Bach, Uma M. Kaipa, Jianing Yao, Joel E. Kleinman, Leonardo Collado-Torres, Shizhong Han, Kristen R. Maynard, Thomas M. Hyde, Keri Martinowich, Stephanie C. Page […]