Kavli Affiliate: Michael Miller | Authors: Zinan Zhou, Lovelace J Luquette, Guanlan Dong, Junho Kim, Jayoung Ku, Kisong Kim, Mingyun Bae, Diane D Shao, Bezawit Sahile, Michael B Miller, August Yue Huang, Peter J Park, Clotilde Lagier-Tourenne, Eunjung Alice Lee and Christopher A Walsh | Summary: Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer’s […]
Kavli Affiliate: Michael Miller | Authors: Guanlan Dong, Chanthia C Ma, Shulin Mao, Samuel M Naik, Katherine Sun-Mi Brown, Gannon A McDonough, Junho Kim, Samantha L Kirkham, Jonathan Cherry, Madeline Uretsky, Elizabeth Spurlock, Ann McKee, August Yue Huang, Michael B Miller, Eunjung Alice Lee and Christopher A Walsh | Summary: Chronic traumatic encephalopathy (CTE) is […]
Kavli Affiliate: Xingde Li | Authors: Fengquan Liu and Xingde Li | Summary: Dispersion mismatch in optical coherence tomography (OCT) is typically addressed through either physical or digital compensation. In this study, we investigate the impact of dispersion on OCT detection sensitivity and compare the effectiveness of physical and digital compensation across varying degrees of […]
Kavli Affiliate: Jin Kang | Authors: Mandeep S Singh, Shoujing Guo, Christopher B Toomey, Minda M McNally, Sarah Harris-Bookman, Kang V Li, Dzhalal Agakishiev, Shuwen Wei, Soohyun Lee, Kathleen Perrino, Kevin C Wolfe and Jin Kang | Summary: Purpose Regenerative therapies for retinal diseases include cell and gene therapy modalities that are targeted to the […]
Kavli Affiliate: Xingde Li | Authors: Yuehan Liu, Jiayun Laurie Huang and Xingde Li | Summary: Miniaturized two-photon imaging devices enable real-time in vivo and in situ imaging at subcellular resolution, highly valuable for clinical applications and basic research (such as neuroscience). However, achieving high-quality volumetric imaging at varying depths remains challenging. In this study, […]
Kavli Affiliate: Brian Caffo | Authors: Chris Acha, Derosh George, Lauren C. Diaz, Ziwei Ouyang, Dowlette-Mary M. Alam El Din, Hrishikesh Surlekar, Babak Moghadas, Pratyush Sai R. Rayasam, Yu-Chiao Lai, Lena Smirnova, Brian S. Caffo, Erik C. Johnson and David H. Gracias | Summary: Neural organoids (NOs) have emerged as important tissue engineering models for […]
Kavli Affiliate: Michael Miller | Authors: Rebecca Melton, Sara Jimenez, Weston Elison, Luca Tucciarone, Abigail Howell, Gaowei Wang, Denise Berti, Elisha Beebe, Michael Miller, Chun Zeng, Kennedy Vanderstel, Katha Korgaonkar, Ruth Elgamal, Hannah Mummey, Josh Chiou, Emily Griffin, Irina Kusmartseva, Mark A. Atkinson, Sebastian Preissl, Fabian Theis, Maike Sander and Kyle J Gaulton | Summary: […]
Kavli Affiliate: Donald Geman | Authors: An Wang, Stephanie C Hicks, Donald Geman and Laurent Younes | Summary: The selection of marker gene panels is critical for capturing the cellular and spatial heterogeneity in the expanding atlases of single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics data. Most current approaches to marker gene selection operate in […]
Kavli Affiliate: Reza Shadmehr | Authors: Paul Hage, Mohammad Amin Fakharian, Alden M. Shoup, Jay S Pi, Ehsan Sedaghat-Nejad, Simon P Orozco, In Kyu Jang, Vivian Looi, Toren Arginteanu and Reza Shadmehr | Summary: We use our tongue much like our hands: to interact with objects and transport them. For example, we use our hands […]
Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Sherine Awad, Isabella Palazzo, Thanh Hoang and Seth Blackshaw | Summary: Retinal Müller glia in cold-blooded vertebrates can reprogram into neurogenic progenitors to replace neurons lost to injury, but mammals lack this ability. While recent studies have shown that transgenic overexpression of neurogenic bHLH factors and glial-specific […]