GIAnT: a Glutamate Imaging Analysis Toolbox

Kavli Affiliate: Adam S. Charles | Authors: Michael E. Xie, Johannes Friedrich, Elizabeth Wirsching, Caleb Jones Shibu, Maedeh Seyedolmohadesin, Naveen Ouellette, Tim Wang, Karel Svoboda, Adam S Charles and Kaspar Podgorski | Summary: Recent advances in fluorescent indicators and optical microscopy now enable in vivo synaptic imaging of glutamate, which transmits the majority of signals between neurons […]


Continue.. GIAnT: a Glutamate Imaging Analysis Toolbox

Bats decouple sonar gaze from steering to resolve sensory conflict

Kavli Affiliate: Cynthia F. Moss | Authors: Nikita M Finger, Shivam S Chitnis, Grace Capshaw, Alara Kaplanoglu, Anand Krishnan and Cynthia F Moss | Summary: When sensory modalities yield conflicting information, animals must rapidly reassess stimuli to select their actions. We induced auditory–visual conflict in free-flying echolocating Egyptian fruit bats, by fitting animals with prisms […]


Continue.. Bats decouple sonar gaze from steering to resolve sensory conflict

SLAy-ing oversplitting errors in high-density electrophysiology spike sorting

  Kavli Affiliate: Adam S. Charles and Kathleen Cullen | Authors: Sai Koukuntla, Tate DeWeese, Alexandra Cheng, Robyn Mildren, Aamna Lawrence, Austin R Graves, Kathleen E Cullen, Jennifer Colonell, Timothy D Harris and Adam S Charles | Summary: The growing channel count of silicon probes has substantially increased the number of neurons recorded in electrophysiology […]


Continue.. SLAy-ing oversplitting errors in high-density electrophysiology spike sorting

Behavioural and neural mechanisms for stochastic choices in mixed strategy games

  Kavli Affiliate: Daeyeol Lee | Authors: Joanna Aloor, Timothy PH Sit, Oliver M Gauld, Joseph Warren, Matthew Mower, Daeyeol Lee and Chunyu A. Duan | Summary: Adaptive behaviour usually requires exploiting regularities in the environment, but in competitive settings the opposite can be true: predictable choice patterns can be exploited by others, making unpredictability […]


Continue.. Behavioural and neural mechanisms for stochastic choices in mixed strategy games

Microglia extract neuronal proteolytic organelles via skoupocytosis

  Kavli Affiliate: Dwight Bergles | Authors: Renee Pepper, Jacqueline M. Griswold, Frances Middleton-Davis, Sarah Syed, Yuuta Imoto, Lani Tran, Eunbin Park, Yu Kang T. Xu, Dwight Bergles, JoAnn Buchanan and Shigeki Watanabe | Summary: Neurons face unique challenges in maintaining protein homeostasis due to their tortuous morphology and extended processes. Proteolytic organelles are typically […]


Continue.. Microglia extract neuronal proteolytic organelles via skoupocytosis

The Live Concert of Brains: Performer-Audience Neural Coupling Links Ensemble Coordination to Shared Audience Integration

  Kavli Affiliate: Xiaoqin Wang | Authors: Yue Ding, Jiameng Liu, Yifan Xu, Li Ji, Yubo Gao, Zheng Liang, Yingying Tang, Juan Huang, Xiaoqin Wang and Dan Zhang | Summary: Collective social events often require coordinated action by one group to become shared experience in another, yet how this transformation is organized across multiple brains […]


Continue.. The Live Concert of Brains: Performer-Audience Neural Coupling Links Ensemble Coordination to Shared Audience Integration

Older adults do not have a higher metabolic cost than younger adults in outdoor overground walking.

  Kavli Affiliate: Michael Miller | Authors: Eline van der Kruk, Koen Jongbloed, Monica Orlandi, Michael Miller and Anne Silverman | Summary: The metabolic cost of walking is widely used to evaluate human performance and effectiveness of clinical interventions. Decades of laboratory research, largely based on treadmill experiments, have established a canonical relationship between walking […]


Continue.. Older adults do not have a higher metabolic cost than younger adults in outdoor overground walking.

The State of Motion: Demographic and representational consequences of motion-based exclusion in fMRI

  Kavli Affiliate: Martin Lindquist | Authors: Patrick Sadil, Briha Ansari, Agostina Casamento-Moran, Ann S. Choe, Jungin Choi, Farzad V. Farahani, Lukman E. Ismaila, Micah Alan Johnson, Arunkumar Kannan, Mary Beth Nebel, James J. Pekar, Haris Iqbal Sair, Joshua Stim, Adrian M. Svingos, Tor D. Wager and Martin A. Lindquist | Summary: Large-scale neuroimaging datasets […]


Continue.. The State of Motion: Demographic and representational consequences of motion-based exclusion in fMRI

Heterogeneous responses to embryonic critical period perturbations within the Drosophila larval locomotor circuit.

Kavli Affiliate: Michael Miller | Authors: Niklas Krick, Jacob Davies, Bramwell Coulson, Daniel Sobrido-Camean, Michael Miller, Matthew C.W. Oswald, Aref Arzan Zarin, Richard Baines and Matthias Landgraf | Summary: As developing neural circuits become functional, they undergo a phase of heightened plasticity that facilitates network tuning in response to intrinsic and/or extrinsic stimuli. These developmental […]


Continue.. Heterogeneous responses to embryonic critical period perturbations within the Drosophila larval locomotor circuit.

High Axial Resolution Is Necessary for Quantitative Two-Photon Calcium Imaging of Neuronal Populations

  Kavli Affiliate: Adam S. Charles | Authors: Ha Yun Anna Yoon, Umaima Afifa, Génesis Ferrer-Imbert, Adam S Charles and Na Ji | Summary: Two-photon calcium imaging is a standard tool for measuring neuronal population activity in vivo, yet how axial resolution, sensor expression strategy, and analysis pipeline jointly affect data accuracy remains poorly characterized. Here, […]


Continue.. High Axial Resolution Is Necessary for Quantitative Two-Photon Calcium Imaging of Neuronal Populations