Kavli Affiliate: Scott Small | Authors: Graham Gower, Nathaniel S. Pope, Murillo F. Rodrigues, Silas Tittes, Linh N. Tran, Ornob Alam, Maria Izabel Alves Cavassim, Peter D. Fields, Benjamin C. Haller, Xin Huang, Ben Jeffrey, Kevin Korfmann, Christopher C. Kyriazis, Jiseon Min, Ines Rebollo, Clara T Rehmann, Scott T. Small, Christopher C. R. Smith, Georgia […]
Kavli Affiliate: Stefano Fusi and René Hen | Authors: Jack E Berry, Jessica C Jimenez, Wei-Li Chang, Kenechukwu Michael Ogbu, Nicholas Manfred, Karly Tegang, Stefano Fusi, René Hen and Clay Lacefield | Summary: In addition to its role in episodic memory and spatial navigation, the hippocampus has also been found to influence mood-related disorders such […]
Kavli Affiliate: Vincent Ferrera | Authors: Alec J. Batts, Robin Ji, Sua Bae, Fotios N. Tsitsos, Sergio Jiménez-Gambín, Nancy Kwon, Samantha L. Gorman, Deny Tsakri, Rebecca L. Noel, Jonas Bendig, Daniella A. Jimenez, Melody DiBenedetto, Sofia A. Del Castillo, Filimon B. Keleta, James Caicedo, Alexander Romanov, Colleen T. Curley, Yulia Dzhashiashvili, Greglynn D. Walton-Gibbs, Bradley […]
Kavli Affiliate: Michael Goldberg | Authors: Francesca Cipressa, Gaelle Pennarun, Giuseppe Bosso, Serena Rosignoli, Liliana Tullo, Nadia Schiralli, Chiara Borghi, Alessandro Paiardini, Michael L Goldberg, Pascale Bertrand and Giovanni Cenci | Summary: Separase is a well conserved endopeptidase that facilitates sister chromatid separation at the metaphase-anaphase transition by cleaving cohesins. Beyond its role in chromosome […]
Kavli Affiliate: Franck Polleux | Authors: Sergio B. Garcia, Alexa P. Schlotter, Daniela Pereira, Aleksandra J Recupero, Franck Polleux and Luke A Hammond | Summary: Quantification of dendritic spines is essential for studying synaptic connectivity, yet most current approaches require manual adjustments or the combination of multiple software tools for optimal results. Here, we present […]
Kavli Affiliate: Kenneth Miller | Authors: Peijia Yu, Yuhan Yang, Olivia Gozel, Ian Oldenburg, Mario Dipoppa, Federico Rossi, Kenneth Miller, Hillel Adesnik, Na Ji and Brent Doiron | Summary: In sensory cortex of brain it is often the case that neurons are spatially organized by their functional properties. A hallmark of primary visual cortex (V1) […]
Kavli Affiliate: Stefano Fusi | Authors: Lorenzo Posani, Shuqi Wang, Samuel Muscinelli, Liam Paninski and Stefano Fusi | Summary: A long-standing debate in neuroscience concerns whether individual neurons are organized into functionally distinct populations that encode information differently (“categorical” representations [1–3]) and the implications for neural computation. Here, we systematically analyzed how cortical neurons encode […]
Kavli Affiliate: Aniruddha Das | Authors: Aniruddha Das, Julie Borovicka, Hale Tobin, Shruti Bhatia, Jacob Icardi, Ghazaal Tahmasebi, Priyanka Agochiya, Shriya Singh, Bruce Trapp and Hod Dana | Summary: Damage to the myelin sheath that protects axons in the central nervous system is a hallmark pathology of demyelinating diseases like multiple sclerosis. Cuprizone-induced demyelination in […]
Kavli Affiliate: Michael Shadlen | Authors: Ariel Zylberberg and Michael N Shadlen | Summary: Confidence in a decision is the belief, prior to feedback, that one’s choice is correct. In the brain, many decisions are implemented as a race between competing evidence-accumulation processes. We ask whether the neurons that represent evidence accumulation also carry information […]
Kavli Affiliate: Kenneth Miller | Authors: Mauro M. Monsalve-Mercado and Kenneth D Miller | Summary: How do populations of neurons collectively encode and process information during cognitive tasks? We analyze high-yield population recordings from the macaque lateral intraparietal area (LIP) during a reaction-time random-dot-motion direction-discrimination task. We find that the trajectories of neural population activity […]