Striatal ensembles specify and control ongoing actions at fine motor resolution

Kavli Affiliate: Rui Costa and Darcy Peterka | Authors: nes Rodrigues-Vaz, Vivek R. Athalye, Helio F. M. Rodrigues, Darcy S. Peterka and Rui M. Costa | Summary: The striatum is classically thought to modulate action vigor and reinforcement, but whether it specifies and controls ongoing actions at a fine scale remains unclear. Here, we test […]


Continue.. Striatal ensembles specify and control ongoing actions at fine motor resolution

Striatal ensembles specify and control granular forelimb actions

Kavli Affiliate: Rui Costa and Darcy Peterka | Authors: Ines Rodrigues-Vaz, Vivek R. Athalye, Darcy S. Peterka and Rui M. Costa | Summary: The striatum is classically thought to modulate action vigor and reinforcement, but whether it specifies and controls ongoing actions at a fine scale remains unclear. Here, we test whether striatal activity can […]


Continue.. Striatal ensembles specify and control granular forelimb actions

Connectivity Logic of Dendritic Spines in Cortex: Increased Inputs and Ensemble Formation

Kavli Affiliate: Rafael Yuste | Authors: Dean Geckt, Netanel Ofer, Michael W. Reimann, Rafael Yuste and Idan Segev | Summary: Dendritic spines, small protrusions covering the dendrites of most neurons, are fundamental elements of synaptic connectivity, yet their network-level organization remains poorly understood. Here we leverage the large-scale MICrONS volumetric electron microscopy dataset of mouse […]


Continue.. Connectivity Logic of Dendritic Spines in Cortex: Increased Inputs and Ensemble Formation

Flexible route planning and rapid structure learning by mice in complex environments

Kavli Affiliate: Rui Costa | Authors: Michael Pereira, Beatriz S. Godinho, Christian K. Machens, Rui M. Costa and Thomas Akam | Summary: Action selection using predictive models of the environment plays a fundamental role in human and animal behaviour, yet is poorly understood at circuit and algorithmic levels. Spatial navigation is an attractive domain for […]


Continue.. Flexible route planning and rapid structure learning by mice in complex environments

Emergence of social recognition in auditory and integrative circuits during pair bonding

Kavli Affiliate: Sarah Woolley | Authors: Erin M Wall, Nicholas Vidas-Guscic, Jasmien Orije, Elisabeth Jonckers, Marleen Verhoye, Annemie Van der Linden and Sarah Cushing Woolley | Summary: Social relationships profoundly shape the perception of communication signals. In animals that form long-term social bonds, sensory cues such as vocalizations, scent, or physical appearance, and rewarding mating […]


Continue.. Emergence of social recognition in auditory and integrative circuits during pair bonding

GPU accelerated population genetics statistics using pg_gpu

Kavli Affiliate: Scott Small | Authors: Yukun A Hao, Lorna Louise Jayne, Sungmoo Lee, Mia Nicole Dittrich, Manze Zhang, Simon Haziza, Imane Bendifallah, Ruth R. Sims, Boris Bouazza-Arostegui, Alexander D White, John Kochalka, Yu Wang, Maedeh Seyedolmohadesin, Adrian Negrean, Zhaoyang Li, Collin Chiu, Kaspar Podgorski, Jun B. Ding, Karl Deisseroth, Rafael Yuste, VALENTINA EMILIANI, Mark […]


Continue.. GPU accelerated population genetics statistics using pg_gpu

Ultrasensitive voltage imaging reveals distinct electrical microdomains in neurons

Kavli Affiliate: Rafael Yuste | Authors: Yukun A Hao, Lorna Louise Jayne, Sungmoo Lee, Mia Nicole Dittrich, Manze Zhang, Simon Haziza, Imane Bendifallah, Ruth R. Sims, Boris Bouazza-Arostegui, Alexander D White, John Kochalka, Yu Wang, Maedeh Seyedolmohadesin, Adrian Negrean, Zhaoyang Li, Collin Chiu, Kaspar Podgorski, Jun B. Ding, Karl Deisseroth, Rafael Yuste, VALENTINA EMILIANI, Mark […]


Continue.. Ultrasensitive voltage imaging reveals distinct electrical microdomains in neurons

Photon-Resolved Excitation-Denoised (PRED) Three-Photon Imaging Improves Detection of Neuronal Activity in Awake and Behaving Mice

Kavli Affiliate: Attila Losonczy and Darcy Peterka | Authors: Attila Losonczy, Tiberiu S Mihaila, Eunji Kong, Adrian Negrean, Tristan Geiller and Darcy S Peterka | Summary: Three-photon microscopy (3PM) has enabled the optical access of neurons ∼500-1500µm below the brain surface but has been limited to slow imaging frame rates or small imaged area due […]


Continue.. Photon-Resolved Excitation-Denoised (PRED) Three-Photon Imaging Improves Detection of Neuronal Activity in Awake and Behaving Mice

Ecotypes, Wolbachia, and urbanization shape Culex pipiens population structure in a West Nile virus hotspot

Kavli Affiliate: Scott Small | Authors: Sonia Cebrián-Camisón, Ángel G. Rivera-Colón, Scott T. Small, Jordi Figuerola, Andrew D. Kern, Peter L. Ralph, Aureliano Bombarely and María José Ruiz-López | Summary: Culex pipiens is a major vector of West Nile Virus (WNV) in Europe and has a complex evolutionary history that has been linked to the […]


Continue.. Ecotypes, Wolbachia, and urbanization shape Culex pipiens population structure in a West Nile virus hotspot

Clustered Inputs Maximize Efficiency for Stable Place Field Encoding in Hippocampal Pyramidal Neurons

Kavli Affiliate: Attila Losonczy | Authors: Simone Tasciotti, Daniel Maxim Iascone, Spyridon Chavlis, Luke Hammond, Yardena Katz, Attila Losonczy, Franck Polleaux and Panayiota Poirazi | Summary: How spatial organization of synaptic inputs along the dendritic tree of neurons influence their feature selectivity is a central question in neuroscience. Here, we mapped the three-dimensional distribution of […]


Continue.. Clustered Inputs Maximize Efficiency for Stable Place Field Encoding in Hippocampal Pyramidal Neurons