Flexible route planning and rapid structure learning by mice in complex environments

Kavli Affiliate: Rui Costa | Authors: Michael Pereira, Beatriz S. Godinho, Christian K. Machens, Rui M. Costa and Thomas Akam | Summary: Action selection using predictive models of the environment plays a fundamental role in human and animal behaviour, yet is poorly understood at circuit and algorithmic levels. Spatial navigation is an attractive domain for […]


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Emergence of social recognition in auditory and integrative circuits during pair bonding

Kavli Affiliate: Sarah Woolley | Authors: Erin M Wall, Nicholas Vidas-Guscic, Jasmien Orije, Elisabeth Jonckers, Marleen Verhoye, Annemie Van der Linden and Sarah Cushing Woolley | Summary: Social relationships profoundly shape the perception of communication signals. In animals that form long-term social bonds, sensory cues such as vocalizations, scent, or physical appearance, and rewarding mating […]


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GPU accelerated population genetics statistics using pg_gpu

Kavli Affiliate: Scott Small | Authors: Yukun A Hao, Lorna Louise Jayne, Sungmoo Lee, Mia Nicole Dittrich, Manze Zhang, Simon Haziza, Imane Bendifallah, Ruth R. Sims, Boris Bouazza-Arostegui, Alexander D White, John Kochalka, Yu Wang, Maedeh Seyedolmohadesin, Adrian Negrean, Zhaoyang Li, Collin Chiu, Kaspar Podgorski, Jun B. Ding, Karl Deisseroth, Rafael Yuste, VALENTINA EMILIANI, Mark […]


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Ultrasensitive voltage imaging reveals distinct electrical microdomains in neurons

Kavli Affiliate: Rafael Yuste | Authors: Yukun A Hao, Lorna Louise Jayne, Sungmoo Lee, Mia Nicole Dittrich, Manze Zhang, Simon Haziza, Imane Bendifallah, Ruth R. Sims, Boris Bouazza-Arostegui, Alexander D White, John Kochalka, Yu Wang, Maedeh Seyedolmohadesin, Adrian Negrean, Zhaoyang Li, Collin Chiu, Kaspar Podgorski, Jun B. Ding, Karl Deisseroth, Rafael Yuste, VALENTINA EMILIANI, Mark […]


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Photon-Resolved Excitation-Denoised (PRED) Three-Photon Imaging Improves Detection of Neuronal Activity in Awake and Behaving Mice

Kavli Affiliate: Attila Losonczy and Darcy Peterka | Authors: Attila Losonczy, Tiberiu S Mihaila, Eunji Kong, Adrian Negrean, Tristan Geiller and Darcy S Peterka | Summary: Three-photon microscopy (3PM) has enabled the optical access of neurons ∼500-1500µm below the brain surface but has been limited to slow imaging frame rates or small imaged area due […]


Continue.. Photon-Resolved Excitation-Denoised (PRED) Three-Photon Imaging Improves Detection of Neuronal Activity in Awake and Behaving Mice

Ecotypes, Wolbachia, and urbanization shape Culex pipiens population structure in a West Nile virus hotspot

Kavli Affiliate: Scott Small | Authors: Sonia Cebrián-Camisón, Ángel G. Rivera-Colón, Scott T. Small, Jordi Figuerola, Andrew D. Kern, Peter L. Ralph, Aureliano Bombarely and María José Ruiz-López | Summary: Culex pipiens is a major vector of West Nile Virus (WNV) in Europe and has a complex evolutionary history that has been linked to the […]


Continue.. Ecotypes, Wolbachia, and urbanization shape Culex pipiens population structure in a West Nile virus hotspot

Clustered Inputs Maximize Efficiency for Stable Place Field Encoding in Hippocampal Pyramidal Neurons

Kavli Affiliate: Attila Losonczy | Authors: Simone Tasciotti, Daniel Maxim Iascone, Spyridon Chavlis, Luke Hammond, Yardena Katz, Attila Losonczy, Franck Polleaux and Panayiota Poirazi | Summary: How spatial organization of synaptic inputs along the dendritic tree of neurons influence their feature selectivity is a central question in neuroscience. Here, we mapped the three-dimensional distribution of […]


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Opioids modulate Curiosity-Driven Exploration in Music

Kavli Affiliate: Jacqueline Gottlieb | Authors: Claudia Alvarez-Martin, Raimund Buehler, Xim Cerda-Company, Gemma Cardona, Matthäus Willeit, Jacqueline Pallas Gottlieb, Giorgia Silani and Antoni Rodriguez-Fornells | Summary: Curiosity, a key driver of exploration and learning, is reinforced by reward-related neurochemical systems, yet the role of the opioidergic system in modulating this behavior remains unclear. Music, as […]


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A family portrait of the genomic factors shaping tandem repeat mutagenesis

Kavli Affiliate: Michael Goldberg | Authors: Thomas A Sasani, Michael E Goldberg, Akshay K Avvaru, Thomas J Nicholas, Deborah W Neklason, Egor Dolzhenko, Tom Mokveld, Katherine M Munson, Kendra Hoekzema, Marcelo Ayllon, Eli J Kaufman, David Porubsky, Paul N Valdmanis, Evan E Eichler, Aaron R Quinlan and Harriet Dashnow | Summary: Tandem repeats (TRs) are […]


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Hippocampal representations of partner and novel individuals in monogamous California mice during pair bond formation

Kavli Affiliate: Steven Siegelbaum | Authors: Kimberly Hernandez Palacios, Oshmita Golam, Steven A Siegelbaum and Andres Bendesky | Summary: The hippocampal CA2 region is critical for social novelty recognition memory—the discrimination of whether a conspecific is novel or familiar. However, its role in forming a memory of a pair-bonded mate is unknown. To examine how […]


Continue.. Hippocampal representations of partner and novel individuals in monogamous California mice during pair bond formation