Harnessing Avidity: Quantifying Entropic and Energetic Effects of Linker Length and Rigidity Required for Multivalent Binding of Antibodies to HIV-1 Spikes

Kavli Affiliate: Pamela J. Bjorkman | First 5 Authors: Tal Einav, Shahrzad Yazdi, Aaron Coey, Pamela J. Bjorkman, Rob Phillips | Summary: Due to the low density of envelope (Env) spikes on the surface of HIV-1, neutralizing IgG antibodies rarely bind bivalently using both antigen-binding arms (Fabs) to crosslink between spikes (inter-spike crosslinking), instead resorting […]


Continue.. Harnessing Avidity: Quantifying Entropic and Energetic Effects of Linker Length and Rigidity Required for Multivalent Binding of Antibodies to HIV-1 Spikes

Absolute and arbitrary orientation of single molecule shapes

Kavli Affiliate: Paul W. K. Rothemund | First 5 Authors: Ashwin Gopinath, Chris Thachuk, Anya Mitskovets, Harry A. Atwater, David Kirkpatrick | Summary: DNA origami is a modular platform for the combination of molecular and colloidal components to create optical, electronic, and biological devices. Integration of such nanoscale devices with microfabricated connectors and circuits is […]


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Topological Excitations of Hidden Order in URu$_2$Si$_2$ Under Extreme Electric Fields

Kavli Affiliate: Brad Ramshaw | First 5 Authors: Laurel E Winter, Arkady Shekhter, Brad Ramshaw, Ryan E. Baumbach, Eric D. Bauer | Summary: Quantum materials are epitomized by the influence of collective modes upon their macroscopic properties. Relatively few examples exist, however, whereby coherence of the ground-state wavefunction directly contributes to the conductivity. Notable examples […]


Continue.. Topological Excitations of Hidden Order in URu$_2$Si$_2$ Under Extreme Electric Fields

Optomechanical damping as the origin of sideband asymmetry

Kavli Affiliate: Ya M. Blanter | First 5 Authors: J. D. P. Machado, Ya. M. Blanter, , , | Summary: Sideband asymmetry in cavity optomechanics has been explained by particle creation and annihilation processes, which bestow an amplitude proportional to ‘n+1’ and ‘n’ excitations to each of the respective sidebands. We discuss the issues with […]


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Evidence for a Spatially-Modulated Superfluid Phase of $^3$He under Confinement

Kavli Affiliate: Jeevak M. Parpia | First 5 Authors: Lev V. Levitin, Ben Yager, Laura Sumner, Brian Cowan, Andrew J. Casey | Summary: In superfluid $^3$He-B confined in a slab geometry, domain walls between regions of different order parameter orientation are predicted to be energetically stable. Formation of the spatially-modulated superfluid stripe phase has been […]


Continue.. Evidence for a Spatially-Modulated Superfluid Phase of $^3$He under Confinement

A 1.6:1 Bandwidth Two-Layer Antireflection Structure for Silicon Matched to the 190-310 GHz Atmospheric Window

Kavli Affiliate: Sunil R. Golwala | First 5 Authors: Fabien Defrance, Cecile Jung-Kubiak, Jack Sayers, Jake Connors, Clare deYoung | Summary: Although high-resistivity, low-loss silicon is an excellent material for THz transmission optics, its high refractive index necessitates antireflection treatment. We fabricated a wide-bandwidth, two-layer antireflection treatment by cutting subwavelength structures into the silicon surface […]


Continue.. A 1.6:1 Bandwidth Two-Layer Antireflection Structure for Silicon Matched to the 190-310 GHz Atmospheric Window

Yield precursor dislocation avalanches in small crystals: the irreversibility transition

Kavli Affiliate: Julia R. Greer | First 5 Authors: Xiaoyue Ni, Haolu Zhang, Danilo B. Liarte, Louis W. McFaul, Karin A. Dahmen | Summary: The transition from elastic to plastic deformation in crystalline metals shares history dependence and scale-invariant avalanche signature with other non-equilibrium systems under external loading: dilute colloidal suspensions, plastically-deformed amorphous solids, granular […]


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Compressive Light Field Reconstructions using Deep Learning

Kavli Affiliate: Alyosha Molnar | First 5 Authors: Mayank Gupta, Arjun Jauhari, Kuldeep Kulkarni, Suren Jayasuriya, Alyosha Molnar | Summary: Light field imaging is limited in its computational processing demands of high sampling for both spatial and angular dimensions. Single-shot light field cameras sacrifice spatial resolution to sample angular viewpoints, typically by multiplexing incoming rays […]


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