A neural mechanism for discriminating social threat from social safety

Kavli Affiliate: Steven Siegelbaum | Authors: Pegah Kassraian, Shivani K. Bigler, Diana M. Gilly, Neilesh Shrotri and Steven A. Siegelbaum | Summary: The ability to distinguish a threatening from non-threatening conspecific based on past experience is critical for adaptive social behaviors. Although recent progress has been made in identifying the neural circuits that contribute to […]


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Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions

Kavli Affiliate: Robert Edwards | Authors: Camille N. Pierre, Lily E. Adams, Kara Anasti, Derrick Goodman, Sherry Stanfield-Oakley, John M. Powers, Dapeng Li, Wes Rountree, Yunfei Wang, Robert J. Edwards, S. Munir Alam, Guido Ferrari, Georgia D. Tomaras, Barton F. Haynes, Ralph S. Baric and Kevin Saunders | Summary: Antibodies perform both neutralizing and non-neutralizing […]


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Sub-second periodic radio oscillations in a microquasar

Kavli Affiliate: Feng Yuan | First 5 Authors: Pengfu Tian, Ping Zhang, Wei Wang, Pei Wang, Xiaohui Sun | Summary: Powerful relativistic jets are one of the ubiquitous features of accreting black holes in all scales. GRS 1915+105 is a well-known fast-spinning black-hole X-ray binary with a relativistic jet, termed as a “microquasar”, as indicated […]


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How Does Diffusion Influence Pretrained Language Models on Out-of-Distribution Data?

Kavli Affiliate: Jing Wang | First 5 Authors: Huazheng Wang, Daixuan Cheng, Haifeng Sun, Jingyu Wang, Qi Qi | Summary: Transformer-based pretrained language models (PLMs) have achieved great success in modern NLP. An important advantage of PLMs is good out-of-distribution (OOD) robustness. Recently, diffusion models have attracted a lot of work to apply diffusion to […]


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A Bayesian Regularized and Anotation-Informed Integrative Analysis of Cognition (BRAINIAC)

Kavli Affiliate: Wesley Thompson | Authors: Rong Zablocki, Bohan Xu, Chun-Chieh Fan and Wesley K. Thompson | Summary: Here we present a development of the novel Bayesian Regularized and Anotation-Informed Integrative Analysis of Cognition (BRAINIAC) model. BRAINIAC allows for both estimation of total variance explained by all features for a given cognitive phenotype, as well […]


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Microglial cannabinoid receptor type1 mediates social memory deficits produced by adolescent THC exposure and 16p11.2 duplication

Kavli Affiliate: Solange Brown | Authors: Yuto Hasegawa, Juhyun Kim, Gianluca Ursini, Yan Jouroukhin, Xiaolei Zhu, Yu Miyahara, Feiyi Xiong, Samskruthi Madireddy, Mizuho Obayashi, Beat Lutz, Akira Sawa, Solange P Brown, Mikhail V Pletnikov and Atsushi Kamiya | Summary: Adolescent cannabis use increases the risk for cognitive impairments and psychiatric disorders. Cannabinoid receptor type 1 […]


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Host interactions of novel Crassvirales species belonging to multiple families infecting bacterial host, Bacteroides cellulosilyticus WH2

Kavli Affiliate: Robert Edwards | Authors: Bhavya Papudeshi, Alejandro A Vega, Cole Souza, Sarah K Giles, Vijini Mallawaarachchi, Michael J. Roach, Michelle An, Nicole Jacobson, Katelyn McNair, Maria Fernanda Mora, Karina Pastrana, Lance Boling, Christopjer Leigh, Clarice Cram, Will S Plewa, Susanna R Grigson, George Bouras, Przemyslaw Decewicz, Antoni Luque, Lindsay Droit, Scott Allyn Handley, […]


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Collective dynamics of formin and microtubule and its crosstalk mediated by FHDC1

Kavli Affiliate: Su Guo | Authors: Chee San Tong, Maohan Su, He Sun, Xiang Le Chua, Su Guo, Ravinraj S/O Ramaraj, Ann Gie Lee, Nicole Wen Pei Ong, Yansong Miao and Min Wu | Summary: The coordination between actin and microtubule network is crucial, yet our understanding of the underlying mechanisms remains limited. In this […]


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Exuberant de novo dendritic spine growth in mature neurons

Kavli Affiliate: Hey-Kyoung Lee | Authors: Sarah Kruessel, Ishana Deb, Seungkyu Son, Gabrielle Ewall, Minhyeok Chang, Hey-Kyoung Lee, Won Do Heo and Hyung-Bae Kwon | Summary: Dendritic spines are structural correlates of excitatory synapses maintaining stable synaptic communications. However, this strong spine-synapse relationship was mainly characterized in excitatory pyramidal neurons (PyNs), raising a possibility that […]


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Flat-sky Angular Power Spectra Revisited

Kavli Affiliate: Anthony Challinor | First 5 Authors: Zucheng Gao, Zvonimir Vlah, Anthony Challinor, , | Summary: We revisit the flat-sky approximation for evaluating the angular power spectra of projected random fields by retaining information about the correlations along the line of sight. With broad, overlapping radial window functions, these line-of-sight correlations are suppressed and […]


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