Loss of cilia after neurulation impacts brain development and neuronal activity in larval zebrafish

Posted by klaurent NTNU

Kavli Affiliate: Emre Yaksi | Authors: Percival P D’Gama, Inyoung Jeong, Andreas M Nygaard, Anh-Tuan Trinh, Emre Yaksi and Nathalie Jurisch-Yaksi | Summary: Cilia are slender, hair-like structures extending from cell surfaces and playing essential roles in diverse physiological processes. Within the nervous system, primary cilia contribute to signaling and sensory perception, while motile cilia […]


Continue.. Loss of cilia after neurulation impacts brain development and neuronal activity in larval zebrafish

Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets

Posted by klaurent Columbia

Kavli Affiliate: Rui Costa | Authors: Leslie J Sibener, Alice C Mosberger, Tiffany X Chen, Vivek R Athalye, James M Murray and Rui M Costa | Summary: Reaches are complex movements that are critical for survival, and encompass the control of different aspects such as direction, speed, and endpoint precision. Complex movements have been postulated […]


Continue.. Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets

Serotonin predictively encodes value

Posted by klaurent Hopkins

Kavli Affiliate: Jeremiah Cohen | Authors: Emerson F Harkin, Cooper D Grossman, Jeremiah Y Cohen, Jean-Claude Béïque and Richard Naud | Summary: The in vivo responses of dorsal raphe nucleus (DRN) serotonin neurons to emotionally-salient stimuli are a puzzle. Existing theories centred on reward, surprise, or uncertainty individually account for some aspects of serotonergic activity […]


Continue.. Serotonin predictively encodes value

A Close Look at Ly$α$ Emitters with JWST/NIRCam at $zapprox3.1$

Posted by klaurent Peking

Kavli Affiliate: Linhua Jiang | First 5 Authors: Yixiao Liu, Y. Sophia Dai, Stijn Wuyts, Jia-Sheng Huang, Linhua Jiang | Summary: We study 10 spectroscopically confirmed Ly$alpha$ emitters (LAEs) at $zapprox3.1$ in the UDS field, covered by JWST/NIRCam in the PRIMER program. All LAEs are detected in all NIRCam bands from F090W to F444W, corresponding […]


Continue.. A Close Look at Ly$α$ Emitters with JWST/NIRCam at $zapprox3.1$

Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Posted by klaurent Tokyo

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Keisuke Inomata, Masahiro Kawasaki, Kyohei Mukaida, Tsutomu T. Yanagida, | Summary: The stochastic gravitational wave background (SGWB) recently detected by the PTA collaborations could be the gravitational waves (GWs) induced by curvature perturbations. However, primordial black holes (PBHs) might be overproduced if the SGWB is explained by […]


Continue.. Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Posted by klaurent Tokyo

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Keisuke Inomata, Masahiro Kawasaki, Kyohei Mukaida, Tsutomu T. Yanagida, | Summary: The stochastic gravitational wave background (SGWB) recently detected by the PTA collaborations could be the gravitational waves (GWs) induced by curvature perturbations. However, primordial black holes (PBHs) might be overproduced if the SGWB is explained by […]


Continue.. Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Structural basis of TRPV1 modulation by endogenous bioactive lipids

Posted by klaurent UCSF

Kavli Affiliate: Yifan Cheng | Authors: William Randall Arnold, Adamo S Mancino, Frank R Moss III, Adam Frost, David Julius and Yifan Cheng | Summary: TRP ion channels are modulated by phosphoinositide lipids, but the underlying structural mechanisms remain unclear. The capsaicin- and heat-activated receptor, TRPV1, has served as a model for deciphering lipid modulation, […]


Continue.. Structural basis of TRPV1 modulation by endogenous bioactive lipids

Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice

Posted by klaurent Columbia

Kavli Affiliate: Stavros Lomvardas | Authors: Elizaveta Bashkirova, Nell Klimpert, Kevin Monahan, Christine Campbell, Jason Osinski, Longzhi Tan, Ira Schieren, Ariel Pourmorady, Rebecca Stecky, Gilad Barnea, Xiaoliang Sunney Xie, Ishmail Abdus-Saboor, Benjamin Shykind, Bianca Jones Marlin, Richard Gronostajski, Alexander Fleischmann and Stavros Lomvardas | Summary: Olfactory receptor (OR) choice represents an example of genetically hardwired […]


Continue.. Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice

Systematics in the Cepheid and TRGB Distance Scales: Metallicity Sensitivity of the Wesenheit Leavitt Law

Posted by klaurent Chicago

Kavli Affiliate: Wendy L. Freedman | First 5 Authors: Barry F. Madore, Wendy L. Freedman, , , | Summary: Using an updated and significantly augmented sample of Cepheid and TRGB distances to 28 nearby spiral and irregular galaxies, covering a wide range of metallicities, we have searched for evidence of a correlation of the zero-point […]


Continue.. Systematics in the Cepheid and TRGB Distance Scales: Metallicity Sensitivity of the Wesenheit Leavitt Law

First X-ray polarization measurement confirms the low black-hole spin in LMC X-3

Posted by klaurent MIT

Kavli Affiliate: Herman L. Marshall | First 5 Authors: Jiří Svoboda, Michal Dovčiak, James F. Steiner, Fabio Muleri, Adam Ingram | Summary: X-ray polarization is a powerful tool to investigate the geometry of accreting material around black holes, allowing independent measurements of the black hole spin and orientation of the innermost parts of the accretion […]


Continue.. First X-ray polarization measurement confirms the low black-hole spin in LMC X-3