klaurent – Page 277 – Kavli Institute Pre-Print Publications

Synergistic effect of mutations in the Parkinson’s disease-linked endocytic proteins synaptojanin 1 (PARK20) and auxilin (PARK19)

Posted by klaurent March 18, 2022March 28, 2022Yale

Kavli Affiliate: Pietro DeCamilli | Authors: Xin Yi Ng, Yumei Wu, Youneng Lin, Sidra Mohamed Yaqoob, Lois E. Greene, Pietro De Camilli and Mian Cao | Summary: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by defective dopaminergic (DAergic) input to the striatum. Mutations in two genes encoding synaptically-enriched clathrin-uncoating factors, synaptojanin 1 (SJ1) and […]

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Projective LDDMM: Spatially Reconstructing a Story of Rostrally-Dominant Tau in Alzheimer’s Disease

Posted by klaurent March 18, 2022March 28, 2022Hopkins, NTNU

Kavli Affiliate: Michael Miller, Susumu Mori, Menno Witter | Authors: Kaitlin Stouffer, Menno Witter, Claire Chen, Eileen Xu, Marilyn Albert, Susumu Mori, Juan Troncoso, Daniel Jacob Tward and Michael Miller | Summary: Since Braak’s initial histological observations, it has been recognized that Alzheimer’s disease (AD) neurofibrillary tangles (NFTs) appear in the medial temporal lobe (MTL) […]

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Hypomyelination reduces parvalbumin interneuron density and auditory cortex inhibitory function

Posted by klaurent March 18, 2022March 28, 2022Hopkins

Kavli Affiliate: Patrick Kanold | Authors: Beatriz C Borges, Xiangying Meng, Patrick Long, Patrick O Kanold and Gabriel Corfas | Summary: For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination focused primarily on excitatory cells. Recent evidence showed that axons of inhibitory neurons in the neocortex are […]

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EMPRESS. VIII. A New Determination of Primordial He Abundance with Extremely Metal-Poor Galaxies: A Suggestion of the Lepton Asymmetry and Implications for the Hubble Tension

Posted by klaurent March 17, 2022March 28, 2022Tokyo

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Akinori Matsumoto, Masami Ouchi, Kimihiko Nakajima, Masahiro Kawasaki, Kai Murai | Summary: The primordial He abundance $Y_P$ is a powerful probe of cosmology. Currently, $Y_P$ is best determined by observations of metal-poor galaxies, while there are only a few known local extremely metal-poor ($<0.1 Z_odot$) galaxies (EMPGs) […]

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EMPRESS. VIII. A New Determination of Primordial He Abundance with Extremely Metal-Poor Galaxies: A Suggestion of the Lepton Asymmetry and Implications for the Hubble Tension

Posted by klaurent March 17, 2022Tokyo

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Akinori Matsumoto, Masami Ouchi, Kimihiko Nakajima, Masahiro Kawasaki, Kai Murai | Summary: The primordial He abundance $Y_mathrm{P}$ is a powerful probe of cosmology. Currently, $Y_mathrm{P}$ is best determined by observations of metal-poor galaxies, while there are only a few known local extremely metal-poor ($<0.1 Z_odot$) galaxies (EMPGs) […]

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Radio pulsations from a neutron star within the gamma-ray binary LS I +61$^{circ}$ 303

Posted by klaurent March 17, 2022March 28, 2022Peking

Kavli Affiliate: Renxin Xu | First 5 Authors: Shan-Shan Weng, Lei Qian, Bo-Jun Wang, D. F. Torres, A. Papitto | Summary: LS I +61$^{circ}$ 303 is one of the rare gamma-ray binaries, emitting most of their luminosity in photons with energies beyond 100 MeV. The $sim$26.5 d orbital period is clearly detected at many wavelengths. […]

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The Aemulus Project V: Cosmological constraint from small-scale clustering of BOSS galaxies

Posted by klaurent March 17, 2022Stanford

Kavli Affiliate: Risa H. Wechsler | First 5 Authors: Zhongxu Zhai, Jeremy L. Tinker, Arka Banerjee, Joseph DeRose, Hong Guo | Summary: We analyze clustering measurements of BOSS galaxies using a simulation-based emulator of two-point statistics. We focus on the monopole and quadrupole of the redshift-space correlation function, and the projected correlation function, at scales […]

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Near-Zone Symmetries of Kerr Black Holes

Posted by klaurent March 16, 2022March 28, 2022Chicago

Kavli Affiliate: Austin Joyce | First 5 Authors: Lam Hui, Austin Joyce, Riccardo Penco, Luca Santoni, Adam R. Solomon | Summary: We study the near-zone symmetries of a massless scalar field on four-dimensional black hole backgrounds. We provide a geometric understanding that unifies various recently discovered symmetries as part of an SO(4,2) group. Of these, […]

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Discovering the building blocks of dark matter halo density profiles with neural networks

Posted by klaurent March 16, 2022March 28, 2022Chicago

Kavli Affiliate: Brian Nord | First 5 Authors: Luisa Lucie-Smith, Hiranya V. Peiris, Andrew Pontzen, Brian Nord, Jeyan Thiyagalingam | Summary: The density profiles of dark matter halos are typically modeled using empirical formulae fitted to the density profiles of relaxed halo populations. We present a neural network model that is trained to learn the […]

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CUE Vectors: Modular Training of Language Models Conditioned on Diverse Contextual Signals

Posted by klaurent March 16, 2022Stanford

Kavli Affiliate: Zeeshan Ahmed | First 5 Authors: Scott Novotney, Sreeparna Mukherjee, Zeeshan Ahmed, Andreas Stolcke, | Summary: We propose a framework to modularize the training of neural language models that use diverse forms of sentence-external context (including metadata) by eliminating the need to jointly train sentence-external and within-sentence encoders. Our approach, contextual universal embeddings […]

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