Characterizing cell-type spatial relationships across length scales in spatially resolved omics data

Kavli Affiliate: Jean Fan | Authors: Rafael dos Santos Peixoto, Brendan F Miller, Maigan A Brusko, Lyla Atta, Manjari Anant, Mark A Atkinson, Todd M Brusko, Clive H Wasserfall and Jean Fan | Summary: Spatially resolved omics technologies provide molecular profiling of cells while preserving their organization within tissues, allowing for the evaluation of cell-type […]


Continue.. Characterizing cell-type spatial relationships across length scales in spatially resolved omics data

Gapped-kmer sequence modeling robustly identifies regulatory vocabularies and distal enhancers conserved between evolutionarily distant mammals

Kavli Affiliate: Michael Beer | Authors: Jin Woo Oh and Michael A Beer | Summary: Gene regulatory elements drive many complex biological phenomena such as fetal development, and their mutations are linked to a multitude of common human diseases. The phenotypic impacts of regulatory variants are often tested using their conserved orthologous counterparts in model […]


Continue.. Gapped-kmer sequence modeling robustly identifies regulatory vocabularies and distal enhancers conserved between evolutionarily distant mammals

Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model

Kavli Affiliate: Michael J Higley | Authors: Samantha Bottom-Tanzer, Sofia Corella, Jochen Meyer, Mary Sommer, Luis Bolanos, Timothy Murphy, Sadi Quinones, Shane Heiney, Matthew Shtrahman, Michael Whalen, Rachel Oren, Michael J Higley, Jessica A Cardin, Farzad Noubary, Moritz Armbruster and Chris Dulla | Summary: Traumatic brain injury (TBI) is the leading cause of death in […]


Continue.. Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model

Structure-Function Coupling in Highly Sampled Individual Brains

Kavli Affiliate: Deanna J. Greene | Authors: Aishwarya Rajesh, Nicole A. Seider, Dillan J. Newbold, Babatunde Adeyemo, Scott Marek, Deanna J. Greene, Abraham Z Snyder, Joshua S. Shimony, Timothy O Laumann, Nico U.F. Dosenbach and Evan M. Gordon | Summary: Structural connections (SC) between distant regions of the brain support synchronized function known as functional […]


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Mice require proprioception to establish long-term visuospatial memory

Kavli Affiliate: Michael Goldberg | Authors: Michael E. Goldberg, Olivia Rutler, Randy M. Bruno, Jung Man Park, Serena Persaud, Stylianos Kosmidis and Nina Hirano | Summary: Because the retina moves constantly, the retinotopic representation of the visual world is spatially inaccurate and the brain must transform this spatially inaccurate retinal signal to a spatially accurate […]


Continue.. Mice require proprioception to establish long-term visuospatial memory

Phonon engineering of atomic-scale defects in superconducting quantum circuits

Kavli Affiliate: Oskar Painter | First 5 Authors: Mo Chen, John Clai Owens, Harald Putterman, Max Schäfer, Oskar Painter | Summary: Noise within solid-state systems at low temperatures, where many of the degrees of freedom of the host material are frozen out, can typically be traced back to material defects that support low-energy excitations. These […]


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Synaptic Basis of Behavioral Timescale Plasticity

Kavli Affiliate: Franck Polleux, Attila Losonczy | Authors: Kevin C Gonzalez, Adrian Negrean, Zhenrui Liao, Franck Polleux and Attila Losonczy | Summary: Learning and memory are fundamental to adaptive behavior and cognition. Various forms of synaptic plasticity have been proposed as cellular substrates for the emergence of feature selectivity in neurons underlying episodic memory. However, […]


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The Supersonic Project: Lighting up the faint end of the JWST UV luminosity function

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Claire E. Williams, William Lake, Smadar Naoz, Blakesley Burkhart, Tommaso Treu | Summary: The James Webb Space Telescope (JWST) is capable of probing extremely early eras of our Universe when the supersonic relative motions between dark matter and baryonic overdensities modulate structure formation ($z>sim 10$). We study […]


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Looking in the axion mirror: An all-sky analysis of stimulated decay

Kavli Affiliate: Kiyoshi Wesley Masui | First 5 Authors: Yitian Sun, Katelin Schutz, Harper Sewalls, Calvin Leung, Kiyoshi Wesley Masui | Summary: Axion dark matter (DM) produces echo images of bright radio sources via stimulated decay. These images appear as a faint radio line centered at half the axion mass, with the line width set […]


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The THESAN project: connecting ionized bubble sizes to their local environments during the Epoch of Reionization

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Meredith Neyer, Aaron Smith, Rahul Kannan, Mark Vogelsberger, Enrico Garaldi | Summary: An important characteristic of cosmic reionization is the growth of ionized gas bubbles surrounding early luminous objects. Understanding the connections between the formation and coalescence of these bubbles and their originating astrophysical sources is equally […]


Continue.. The THESAN project: connecting ionized bubble sizes to their local environments during the Epoch of Reionization