A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane

Kavli Affiliate: Pietro DeCamilli | Authors: Andrés Guillén Samander, Yumei Wu, S. Sebastian Pineda, Francisco J. García, Julia N. Eisen, Marianna Leonzino, Berrak Uğur, Manolis Kellis, Myriam Heiman and Pietro De Camilli | Summary: Chorea-acanthocytosis and McLeod syndrome are diseases with shared clinical manifestations caused by mutations in VPS13A and XK, respectively. Key features of […]


Continue.. A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane

Knowledge-Spreader: Learning Facial Action Unit Dynamics with Extremely Limited Labels

Kavli Affiliate: Xiang Zhang | First 5 Authors: Xiaotian Li, Xiang Zhang, Taoyue Wang, Lijun Yin, | Summary: Recent studies on the automatic detection of facial action unit (AU) have extensively relied on large-sized annotations. However, manually AU labeling is difficult, time-consuming, and costly. Most existing semi-supervised works ignore the informative cues from the temporal […]


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Mesoscopic oblique plane microscopy (Meso-OPM) – enabling large-scale 4D isotropic cellular resolution imaging with a diffractive light sheet

Kavli Affiliate: Patrick Kanold | Authors: Wenjun Shao, Minzi Chang, Kevin Emmerich, Patrick O Kanold, Jeff S Mumm and Ji Yi | Summary: Fundamental understanding of large-scale dynamic connectivity within a living organism requires volumetric imaging over a large field of view (FOV) at biologically relevant speed and resolution. However, most microscopy methods make trade-offs […]


Continue.. Mesoscopic oblique plane microscopy (Meso-OPM) – enabling large-scale 4D isotropic cellular resolution imaging with a diffractive light sheet

A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

Kavli Affiliate: Yi Zhou | First 5 Authors: Ziyi Chen, Bhavya Kailkhura, Yi Zhou, , | Summary: Many important machine learning applications involve regularized nonconvex bi-level optimization. However, the existing gradient-based bi-level optimization algorithms cannot handle nonconvex or nonsmooth regularizers, and they suffer from a high computation complexity in nonconvex bi-level optimization. In this work, […]


Continue.. A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

Kavli Affiliate: Yi Zhou | First 5 Authors: Ziyi Chen, Bhavya Kailkhura, Yi Zhou, , | Summary: Many important machine learning applications involve regularized nonconvex bi-level optimization. However, the existing gradient-based bi-level optimization algorithms cannot handle nonconvex or nonsmooth regularizers, and they suffer from a high computation complexity in nonconvex bi-level optimization. In this work, […]


Continue.. A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

Mesoscopic oblique plane microscopy (Meso-OPM) with a diffractive light sheet- enabling large-scale 4D cellular resolution imaging

Kavli Affiliate: Patrick Kanold | Authors: Wenjun Shao, Minzi Chang, Kevin Emmerich, Patrick O Kanold, Jeff S Mumm and Ji Yi | Summary: Abstract Fundamental understanding of large-scale dynamic connectivity within a living organism requires volumetric imaging over a large field of view (FOV) at biologically relevant speed and resolution. However, most microscopy methods make […]


Continue.. Mesoscopic oblique plane microscopy (Meso-OPM) with a diffractive light sheet- enabling large-scale 4D cellular resolution imaging

Why are we still using 3D masses for cluster cosmology?

Kavli Affiliate: Salman Habib | First 5 Authors: Stijn N. B. Debackere, Henk Hoekstra, Joop Schaye, Katrin Heitmann, Salman Habib | Summary: The abundance of clusters of galaxies is highly sensitive to the late-time evolution of the matter distribution, since clusters form at the highest density peaks. However, the 3D cluster mass cannot be inferred […]


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The Chemical Composition of Extreme-Velocity Stars

Kavli Affiliate: Anna Frebel | First 5 Authors: Henrique Reggiani, Alexander P. Ji, Kevin C. Schlaufman, Anna Frebel, Lina Necib | Summary: Little is known about the origin of the fastest stars in the Galaxy. Our understanding of the Milky Way and surrounding dwarf galaxies chemical evolution history allows us to use the chemical composition […]


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Learning to Socially Navigate in Pedestrian-rich Environments with Interaction Capacity

Kavli Affiliate: Jing Wang | First 5 Authors: Quecheng Qiu, Shunyi Yao, Jing Wang, Jun Ma, Guangda Chen | Summary: Existing navigation policies for autonomous robots tend to focus on collision avoidance while ignoring human-robot interactions in social life. For instance, robots can pass along the corridor safer and easier if pedestrians notice them. Sounds […]


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