Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Posted by klaurent UCSD / Salk

Kavli Affiliate: Jean Pierre Changeux | Authors: Sophie Shi, Solene N Lefebvre, Laurie Peverini, Adrien H Cerdan, Marc Gielen, Jean-Pierre Changeux, Marco CECCHINI and Pierre-Jean Corringer | Summary: Pentameric ligand-gated ion channel mediate signal transduction at chemical synapses by transiting between resting and open states upon neurotransmitter binding. Here, we investigate the gating transition of […]


Continue.. Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Accurate Scoliosis Vertebral Landmark Localization on X-ray Images via Shape-constrained Multi-stage Cascaded CNNs

Posted by klaurent Peking

Kavli Affiliate: Li Xin Li | First 5 Authors: Zhiwei Wang, Jinxin Lv, Yunqiao Yang, Yuanhuai Liang, Yi Lin | Summary: Vertebral landmark localization is a crucial step for variant spine-related clinical applications, which requires detecting the corner points of 17 vertebrae. However, the neighbor landmarks often disturb each other for the homogeneous appearance of […]


Continue.. Accurate Scoliosis Vertebral Landmark Localization on X-ray Images via Shape-constrained Multi-stage Cascaded CNNs

Spatiotemporal recruitment of inhibition and excitation in the mammalian cortex during electrical stimulation

Posted by klaurent UCSF

Kavli Affiliate: Michael Stryker | Authors: Maria C. Dadarlat, Yujiao Jennifer Sun and Michael P Stryker | Summary: Electrical stimulation has emerged as a powerful and precise treatment in which to modulate aberrant neural activity patterns common in neural dysfunction and disease; however, the physiological process involved in microstimulation is poorly understood, particularly regarding the […]


Continue.. Spatiotemporal recruitment of inhibition and excitation in the mammalian cortex during electrical stimulation

All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals

Posted by klaurent Rockefeller

Kavli Affiliate: Cori Bargmann | Authors: Amelie CF Bergs, Jana F Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Johannes Vierock, Cori Bargmann, Peter Hegemann, J. Simon Wiegert and Alexander Gottschalk | Summary: Optogenetics are used to stimulate or inhibit neurons. Because optogenetic stimulation is typically static, neurons […]


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APES: Articulated Part Extraction from Sprite Sheets

Posted by klaurent UCSB

Kavli Affiliate: Matthew Fisher | First 5 Authors: Zhan Xu, Matthew Fisher, Yang Zhou, Deepali Aneja, Rushikesh Dudhat | Summary: Rigged puppets are one of the most prevalent representations to create 2D character animations. Creating these puppets requires partitioning characters into independently moving parts. In this work, we present a method to automatically identify such […]


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NeMF: Neural Motion Fields for Kinematic Animation

Posted by klaurent UCAS

Kavli Affiliate: Yi Zhou | First 5 Authors: Chengan He, Jun Saito, James Zachary, Holly Rushmeier, Yi Zhou | Summary: We present an implicit neural representation to learn the spatio-temporal space of kinematic motions. Unlike previous work that represents motion as discrete sequential samples, we propose to express the vast motion space as a continuous […]


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Recording large-scale, cellular-resolution neuronal activity from freely-moving mice

Posted by klaurent Columbia

Kavli Affiliate: Aniruddha Das | Authors: Aniruddha Das, Sarah Holden, Julie Borovicka, Jacob Icardi, Davina Patel, Rushik Patel, Jacob Raber and Hod Dana | Summary: To date, recording of cellular-resolution activity from awake mice has required either head fixation under a microscope or attaching a miniaturized device to the skull, both of which inevitably affect […]


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A multifaceted architectural framework of the mouse claustrum complex

Posted by klaurent NTNU

Kavli Affiliate: Clifford Kentros, Menno Witter, Stefan Blankvoort | Authors: Joachim Schweder Grimstvedt, Andrew M. Shelton, Anna Hoerder-Suabedissen, David K. Oliver, Christin H. Berndtsson, Stefan Blankvoort, Rajeevkumar Raveendran Nair, Adam M. Packer, Menno P. Witter and Clifford G. Kentros | Summary: Accurate anatomical characterizations are necessary to investigate neural circuitry on a fine scale, but […]


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Anisotropic Gigahertz Antiferromagnetic Resonances of the Easy-Axis van der Waals Antiferromagnet CrSBr

Posted by klaurent Cornell

Kavli Affiliate: Daniel C. Ralph | First 5 Authors: Thow Min Jerald Cham, Saba Karimeddiny, Avalon H. Dismukes, Xavier Roy, Daniel C. Ralph | Summary: We report measurements of antiferromagnetic resonances in the van der Waals easy-axis antiferromagnet CrSBr. The interlayer exchange field and magnetocrystalline anisotropy fields are comparable to laboratory magnetic fields, allowing a […]


Continue.. Anisotropic Gigahertz Antiferromagnetic Resonances of the Easy-Axis van der Waals Antiferromagnet CrSBr

Anisotropic Gigahertz Antiferromagnetic Resonances of the Easy-Axis van der Waals Antiferromagnet CrSBr

Posted by klaurent Cornell

Kavli Affiliate: Daniel C. Ralph | First 5 Authors: Thow Min Cham, Saba Karimeddiny, Avalon H. Dismukes, Xavier Roy, Daniel C. Ralph | Summary: We report measurements of gigahertz-frequency antiferromagnetic resonances that are anisotropic as a function of the direction of applied magnetic field relative to the crystal axes in the van der Waals easy-axis […]


Continue.. Anisotropic Gigahertz Antiferromagnetic Resonances of the Easy-Axis van der Waals Antiferromagnet CrSBr