Fe-TAMLs as a new class of small molecule peroxidase probes for correlated light and electron microscopy

Kavli Affiliate: Mark Ellisman | Authors: Stephen R Adams, Mason R Mackey, Ranjan Ramachandra, Thomas J Deerinck, Guillaume A Castillon, Sebastien Phan, Junru Hu, Daniela Boassa, John T Ngo and Mark H Ellisman | Summary: We introduce Fe-TAML, a small molecule-based peroxidase as a versatile new member of the correlated fluorescence and electron microscopy toolkit. […]


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A Neural Scaling Law from Lottery Ticket Ensembling

Kavli Affiliate: Max Tegmark | First 5 Authors: Ziming Liu, Max Tegmark, , , | Summary: Neural scaling laws (NSL) refer to the phenomenon where model performance improves with scale. Sharma & Kaplan analyzed NSL using approximation theory and predict that MSE losses decay as $N^{-alpha}$, $alpha=4/d$, where $N$ is the number of model parameters, […]


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Integrability of Large-Charge Sectors in Generic 2D EFTs

Kavli Affiliate: Simeon Hellerman | First 5 Authors: Matthew Dodelson, Simeon Hellerman, Masataka Watanabe, Masahito Yamazaki, | Summary: It is shown that integrability is an accidental property of generic two-dimensional $O(2)$-symmetric asymptotically-free theories in the regime where the charge density is much larger than the dynamical scale. We show this by constructing an infinite tower […]


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MAP1B Regulates Cortical Neuron Interstitial Axon Branching Through the Tubulin Tyrosination Cycle

Kavli Affiliate: Alex Kolodkin | Authors: Jakub Ziak, Joelle Dorskind, Brian Trigg, Sriram Sudarsanam, Randal Hand and Alex L Kolodkin | Summary: Regulation of directed axon guidance and branching during development is essential for the generation of neuronal networks. However, the molecular mechanisms that underlie interstitial axon branching in the mammalian brain remain unresolved. Here, […]


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X-ray Polarization of the BL Lac Type Blazar 1ES 0229+200

Kavli Affiliate: Roger W. Romani | First 5 Authors: Steven R. Ehlert, Ioannis Liodakis, Riccardo Middei, Alan P. Marscher, Fabrizio Tavecchio | Summary: We present polarization measurements in the $2-8 thinspace mathrm{keV}$ band from blazar 1ES 0229+200, the first extreme high synchrotron peaked source to be observed by the Imaging X-ray Polarimetry Explorer (IXPE). Combining […]


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Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

Kavli Affiliate: Liam Paninski | Authors: Marcus A. Triplett, Marta Gajowa, Benjamin Antin, Masato Sadahiro, Hillel Adesnik and Liam Paninski | Summary: Abstract Discovering how neural computations are implemented in the cortex at the level of monosynaptic connectivity requires probing for the existence of synapses from possibly thousands of presynaptic candidate neurons. Two-photon optogenetics has […]


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3D photonics for ultra-low energy, high bandwidth-density chip data links

Kavli Affiliate: Alyosha Molnar | First 5 Authors: Stuart Daudlin, Stuart Daudlin, , , | Summary: Artificial intelligence (AI) hardware is positioned to unlock revolutionary computational abilities across diverse fields ranging from fundamental science [1] to medicine [2] and environmental science [3] by leveraging advanced semiconductor chips interconnected in vast distributed networks. However, AI chip […]


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X-ray and Radio Monitoring of the Neutron Star Low Mass X-ray Binary 1A 1744-361: Quasi Periodic Oscillations, Transient Ejections, and a Disk Atmosphere

Kavli Affiliate: Deepto Chakrabarty | First 5 Authors: Mason Ng, Andrew K. Hughes, Jeroen Homan, Jon M. Miller, Sean N. Pike | Summary: We report on X-ray (NICER/NuSTAR/MAXI/Swift) and radio (MeerKAT) timing and spectroscopic analysis from a three-month monitoring campaign in 2022 of a high-intensity outburst of the dipping neutron star low-mass X-ray binary 1A […]


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AGN STORM 2. VI. Mapping Temperature Fluctuations in the Accretion Disk of Mrk 817

Kavli Affiliate: Erin A. Kara | First 5 Authors: Jack M. M. Neustadt, Christopher S. Kochanek, John Montano, Jonathan Gelbord, Aaron J. Barth | Summary: We fit the UV/optical lightcurves of the Seyfert 1 galaxy Mrk 817 to produce maps of the accretion disk temperature fluctuations $delta T$ resolved in time and radius. The $delta […]


Continue.. AGN STORM 2. VI. Mapping Temperature Fluctuations in the Accretion Disk of Mrk 817