Speech Intelligibility Classifiers from 550k Disordered Speech Samples

Kavli Affiliate: Michael P. Brenner | First 5 Authors: Subhashini Venugopalan, Jimmy Tobin, Samuel J. Yang, Katie Seaver, Richard J. N. Cave | Summary: We developed dysarthric speech intelligibility classifiers on 551,176 disordered speech samples contributed by a diverse set of 468 speakers, with a range of self-reported speaking disorders and rated for their overall […]


Continue.. Speech Intelligibility Classifiers from 550k Disordered Speech Samples

Speech Intelligibility Classifiers from 550k Disordered Speech Samples

Kavli Affiliate: Michael P. Brenner | First 5 Authors: Subhashini Venugopalan, Jimmy Tobin, Samuel J. Yang, Katie Seaver, Richard J. N. Cave | Summary: We developed dysarthric speech intelligibility classifiers on 551,176 disordered speech samples contributed by a diverse set of 468 speakers, with a range of self-reported speaking disorders and rated for their overall […]


Continue.. Speech Intelligibility Classifiers from 550k Disordered Speech Samples

Organization and Plasticity of Inhibition in Hippocampal Recurrent Circuits

Kavli Affiliate: Attila Losonczy | Authors: Bert Vancura, Tristan Geiller and Attila Losonczy | Summary: Excitatory-inhibitory interactions structure recurrent network dynamics for efficient cortical computations. In the CA3 area of the hippocampus, recurrent circuit dynamics, including experience-induced plasticity at excitatory synapses, are thought to play a key role in episodic memory encoding and consolidation via […]


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Batch Effects are Causal Effects: Applications in Human Connectomics

Kavli Affiliate: Brian Caffo, Joshua Vogelstein | Authors: Eric W. Bridgeford, Michael Powell, Gregory Kiar, Stephanie Noble, Jaewon Chung, Sambit Panda, Ross Lawrence, Ting Xu, Michael Milham, Brian Caffo and Joshua T. Vogelstein | Summary: Batch effects, undesirable sources of variance across multiple experiments, present a substantial hurdle for scientific and clinical discoveries. Specifically, the […]


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A systematic search for RNA structural switches across the human transcriptome

Kavli Affiliate: Yifan Cheng | Authors: Matvei Khoroshkin, Daniel Asarnow, Albertas Navickas, Aidan Winters, Johnny Yu, Simon K. Zhou, Shaopu Zhou, Christina Palka, Lisa Fish, K. Mark Ansel, Yifan Cheng, Luke A. Gilbert and Hani Goodarzi | Summary: RNA structural switches are key regulators of gene expression in bacteria, yet their characterization in Metazoa remains […]


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Modulation of dependencies by brain states in a laminar cortical circuit

Kavli Affiliate: Anirvan Nandy | Authors: Anirban Das, Alec G. Sheffield, Anirvan S. Nandy and Monika P. Jadi | Summary: Adaptive information processing, comprised of local computations and their efficient routing, is crucial for flexible brain function. Spatial attention is a quintessential example of this adaptive process. It is critical for recognizing and interacting with […]


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A Distributionally Robust Random Utility Model

Kavli Affiliate: David Muller | First 5 Authors: David Müller, Emerson Melo, Ruben Schlotter, , | Summary: This paper introduces the distributionally robust random utility model (DRO-RUM), which allows the preference shock (unobserved heterogeneity) distribution to be misspecified or unknown. We make three contributions using tools from the literature on robust optimization. First, by exploiting […]


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Single-Step Synthesis of Shape-Controlled Polymeric Particles using Initiated Chemical Vapor Deposition in Liquid Crystals

Kavli Affiliate: Nicholas L. Abbott | First 5 Authors: Apoorva Jain, Soumyamouli Pal, Nicholas L. Abbott, Rong Yang, | Summary: The ability to synthesize shape-controlled polymer particles will benefit a wide range of applications including targeted drug delivery and metamaterials with reconfigurable structures, but existing synthesis approaches are commonly multistep and limited to a narrow […]


Continue.. Single-Step Synthesis of Shape-Controlled Polymeric Particles using Initiated Chemical Vapor Deposition in Liquid Crystals

Single-Step Synthesis of Shape-Controlled Polymeric Particles using Initiated Chemical Vapor Deposition in Liquid Crystals

Kavli Affiliate: Nicholas L. Abbott | First 5 Authors: Apoorva Jain, Soumyamouli Pal, Nicholas L. Abbott, Rong Yang, | Summary: The ability to synthesize shape-controlled polymer particles will benefit a wide range of applications including targeted drug delivery and metamaterials with reconfigurable structures, but existing synthesis approaches are commonly multistep and limited to a narrow […]


Continue.. Single-Step Synthesis of Shape-Controlled Polymeric Particles using Initiated Chemical Vapor Deposition in Liquid Crystals