Correcting for Interference in Experiments: A Case Study at Douyin

Kavli Affiliate: Huawei Zhang | First 5 Authors: Vivek F. Farias, Hao Li, Tianyi Peng, Xinyuyang Ren, Huawei Zhang | Summary: Interference is a ubiquitous problem in experiments conducted on two-sided content marketplaces, such as Douyin (China’s analog of TikTok). In many cases, creators are the natural unit of experimentation, but creators interfere with each […]


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Automatic Discovery of Cognitive Strategies with Tiny Recurrent Neural Networks

Kavli Affiliate: Marcelo Mattar | Authors: Li Ji-An, Marcus K Benna and Marcelo G Mattar | Summary: Normative frameworks such as Bayesian inference and reward-based learning are useful tools for explaining the fundamental principles of adaptive behavior. However, their ability to describe realistic animal behavior is limited by the often small number of parameters that […]


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Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal

Kavli Affiliate: Michael Beer | Authors: Bess P. Rosen, Qing V. Li, Hyunwoo Cho, Dingyu Liu, Dapeng Yang, Sarah Graff, Jielin Yan, Renhe Luo, Nipun Verma, Jeyaram R. Damodaran, Michael A. Beer, Simone Sidoli and Danwei Huangfu | Summary: Pluripotent stem cells are defined by both the ability to unlimitedly self-renew and differentiate to any […]


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Inspiraling streams of enriched gas observed around a massive galaxy 11 billion years ago

Kavli Affiliate: Ran Wang | First 5 Authors: Shiwu Zhang, Zheng Cai, Dandan Xu, Rhythm Shimakawa, Fabrizio Arrigoni Battaia | Summary: Stars form in galaxies, from gas that has been accreted from the intergalactic medium. Simulations have shown that recycling of gas-the reaccretion of gas that was previously ejected from a galaxy-could sustain star formation […]


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Learngene: Inheriting Condensed Knowledge from the Ancestry Model to Descendant Models

Kavli Affiliate: Jing Wang | First 5 Authors: Qiufeng Wang, Xu Yang, Shuxia Lin, Jing Wang, Xin Geng | Summary: During the continuous evolution of one organism’s ancestry, its genes accumulate extensive experiences and knowledge, enabling newborn descendants to rapidly adapt to their specific environments. Motivated by this observation, we propose a novel machine learning […]


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Observationally guided models for the solar dynamo and the role of the surface field

Kavli Affiliate: Robert Cameron | First 5 Authors: Robert Cameron, Manfred Schüssler, , , | Summary: Theoretical models for the solar dynamo range from simple low-dimensional “toy models” to complex 3D-MHD simulations. Here we mainly discuss appproaches that are motivated and guided by solar (and stellar) observations. We give a brief overview of the evolution […]


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Distributionally robust chance constrained Markov decision process with Kullback-Leibler divergence

Kavli Affiliate: Jia Liu | First 5 Authors: Tian Xia, Jia Liu, Abdel Lisser, , | Summary: This paper considers the distributionally robust chance constrained Markov decision process with random reward and ambiguous reward distribution. We consider individual and joint chance constraint cases with Kullback-Leibler divergence based ambiguity sets centered at elliptical distributions or elliptical […]


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The Classical Equations of Motion of Quantized Gauge Theories, Part I: General Relativity

Kavli Affiliate: Tom Melia | First 5 Authors: David E. Kaplan, Tom Melia, Surjeet Rajendran, , | Summary: In this and a companion paper, we show that quantum field theories with gauge symmetries permit a broader class of classical dynamics than typically assumed. In this article, we show that the dynamics extracted from the path […]


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Age-related increases in fibroblasts-secreted IGFBP2 increase melanoma cell invasion and lipid synthesis.

Kavli Affiliate: Denis Wirtz | Authors: Gretchen M Alicea, Marie E Portuallo, Payal Patel, Mitchell E Fane, Alexis Carey, David W. Speicher, Andrew Kossenkov, Vito W Rebecca III, Denis Wirtz and Ashani T Weeraratna | Summary: Aged melanoma patients (>65 years old) have more aggressive disease relative to young patients (5-fold levels of insulin-like growth […]


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Diverging maternal and infant cord antibody functions from SARS-CoV-2 infection and vaccination in pregnancy

Kavli Affiliate: Jin Kang | Authors: Emily H. Adhikari, Pei Lu, Ye Jin Kang, Ann R. McDonald, Jessica E. Pruszynski, Timothy A Bates, Savannah K. McBride, Mila Trank-Greene, Fikadu G Tafesse and Lenette L. Lu | Summary: Immunization in pregnancy is a critical tool that can be leveraged to protect the infant with an immature […]


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