Kavli Affiliate: Nathaniel Heintz | Authors: Christina Pressl, Kert Mätlik, Laura Kus, Paul Darnell, Ji-Dung Luo, Alison R Weiss, William Liguore, Thomas Carroll, David A Davis, Jodi McBride and Nathaniel Heintz | Summary: The properties of the cell types that are most vulnerable in the Huntington’s disease (HD) cortex, the nature of somatic CAG expansion […]
Kavli Affiliate: Nathaniel Heintz | Authors: Kert Mätlik, Matthew Baffuto, Laura Kus, David A Davis, Matthew R Paul, Thomas S Carroll and Nathaniel Heintz | Summary: Tissue-specific somatic expansion of the mutant Huntingtin (mHTT) CAG tract and regional degeneration of the brain are key features of Huntington’s disease (HD). However, the relationships between somatic CAG […]
Kavli Affiliate: Loyal Goff | Authors: Debamitra Das, Shreyash Sonthalia, Genevieve G Stein-O’Brien, Marah Wahbeh, Kyra Feuer, Loyal Goff, Carlo Colantuoni, Vasiliki Machairaki and Dimitrios Avramopoulos | Summary: Trans-differentiation of human induced pluripotent stem cells into neurons via Ngn2-induction (hiPSC-N) has become an efficient system to quickly generate neurons for disease modeling and in vitro […]
Kavli Affiliate: Robert Edwards | Authors: Tapsi Kumar, Kevin Nee, Runmin Wei, Siyuan He, Quy Nguyen, Shanshan Bai, Kerrigan Blake, Maren Pein, Yanwen Gong, Emi Sei, Min Hu, Anna Casasent, Aatish Thennavan, Jianzhuo Li, Tuan Tran, Ken Chen, Benedikt Nilges, Nachiket Kashikar, Oliver Braubach, Bassem Cheikh, Nadya Nikulina, Hui Chen, Mediate Teshome, Brian Menegaz, Huma […]
Kavli Affiliate: Feng Wang | First 5 Authors: Lue Fan, Yuxue Yang, Yiming Mao, Feng Wang, Yuntao Chen | Summary: This paper aims for high-performance offline LiDAR-based 3D object detection. We first observe that experienced human annotators annotate objects from a track-centric perspective. They first label the objects with clear shapes in a track, and […]
Kavli Affiliate: Tadayuki Takahashi | First 5 Authors: Tenyo Kawamura, Chris Done, Tadayuki Takahashi, , | Summary: Fast variability of the X-ray corona in black hole binaries can produce a soft lag by reverberation, where the reprocessed thermalized disc photons lag behind the illuminating hard X-rays. This lag is small, and systematically decreases with increasing […]
Kavli Affiliate: Tadayuki Takahashi | First 5 Authors: Tenyo Kawamura, Chris Done, Tadayuki Takahashi, , | Summary: Fast variability of the X-ray corona in black hole binaries can produce a soft lag by reverberation, where the reprocessed thermalized disc photons lag behind the illuminating hard X-rays. This lag is small, and systematically decreases with increasing […]
Kavli Affiliate: Shunsaku Horiuchi | First 5 Authors: Kanji Mori, Tomoya Takiwaki, Kei Kotake, Shunsaku Horiuchi, | Summary: Core-collapse supernovae are a useful laboratory to probe the nature of exotic particles. If axionlike particles (ALPs) are produced in supernovae, they can affect the transfer of energy and leave traces in observational signatures. In this work, […]
Kavli Affiliate: Robert Edwards | Authors: Jody C McKerral, Bhavya Nalagampalli Papudeshi, Laura K Inglis, Michael J Roach, Przemyslaw Decewicz, Katelyn McNair, Antoni Luque, Elizabeth A Dinsdale and Robert A Edwards | Summary: Phages dominate every ecosystem on the planet. While virulent phages sculpt the microbiome by killing their bacterial hosts, temperate phages provide unique […]
Kavli Affiliate: Eric Charles | First 5 Authors: Michela Negro, Milena Crnogorčević, Eric Burns, Eric Charles, Lea Marcotulli | Summary: With the coincident detections of electromagnetic radiation together with gravitational waves (GW170817) or neutrinos (TXS 0506+056), the new era of multimessenger astrophysics has begun. Of particular interest are the searches for correlation between the high-energy […]