ER-phagy drives age-onset remodeling of endoplasmic reticulum structure-function and lifespan

Posted by dbos UCSD / Salk

Kavli Affiliate: Mark Ellisman | Authors: Eric KF Donahue, Nathaniel L Hepowit, Brennen Keuchel, Alexandra G Mulligan, Derek J Johnson, Mark Ellisman, Rafael Arrojo e Drigo, Jason A MacGurn and Kristopher Burkewitz | Summary: The endoplasmic reticulum (ER) comprises an array of structurally distinct subdomains, each with characteristic functions. While altered ER-associated processes are linked […]


Continue.. ER-phagy drives age-onset remodeling of endoplasmic reticulum structure-function and lifespan

Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

Posted by dbos UCSF

Kavli Affiliate: Xin Duan | Authors: Julieta Gomez-Frittelli, Gabrielle Frederique Devienne, Lee Travis, Melinda A Kyloh, Xin Duan, Tim J Hibberd, Nick J Spencer, John R Huguenard and Julia Kaltschmidt | Summary: Intrinsic sensory neurons are an essential part of the enteric nervous system (ENS) and play a crucial role in gastrointestinal tract motility and […]


Continue.. Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology

Posted by dbos Hopkins

Kavli Affiliate: Jin Kang | Authors: Yingying Zhang, Alden K Leung, Jin Joo Kang, Yu Sun, Guanxi Wu, Le Li, Jiayang Sun, Lily Cheng, Tian Qiu, Junke Zhang, Shayne Wierbowski, Shagun Gupta, James Booth and Haiyuan Yu | Summary: A major goal of cancer biology is to understand the mechanisms underlying tumorigenesis driven by somatically […]


Continue.. A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology

Dynamical scaling behavior of the two-dimensional random singlet state in the random $Q$ model

Posted by dbos UCAS

Kavli Affiliate: Long Zhang | First 5 Authors: Chen Peng, Long Zhang, , , | Summary: In this work, we study the scaling relation of energy and length scales in the 2D random-singlet (RS) state of the random $Q$ model. To investigate the intrinsic energy scale of the spinon subsystem arising from the model, we […]


Continue.. Dynamical scaling behavior of the two-dimensional random singlet state in the random $Q$ model

Dynamical scaling behavior of the two-dimensional random singlet state in the random $Q$ model

Posted by dbos UCAS

Kavli Affiliate: Long Zhang | First 5 Authors: Chen Peng, Long Zhang, , , | Summary: In this work, we study the scaling relation of energy and length scales in the 2D random-singlet (RS) state of the random $Q$ model. To investigate the intrinsic energy scale of the spinon subsystem arising from the model, we […]


Continue.. Dynamical scaling behavior of the two-dimensional random singlet state in the random $Q$ model

TOI-2490b- The most eccentric brown dwarf transiting in the brown dwarf desert

Posted by dbos MIT

Kavli Affiliate: Sara Seager | First 5 Authors: Beth A. Henderson, Sarah L. Casewell, Andrés Jordán, Rafael Brahm, Thomas Henning | Summary: We report the discovery of the most eccentric transiting brown dwarf in the brown dwarf desert, TOI02490b. The brown dwarf desert is the lack of brown dwarfs around main sequence stars within $sim3$~AU […]


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The Transition from Galaxy-wide Gas Inflow to Outflow in Quasar Host Galaxies

Posted by dbos Peking

Kavli Affiliate: Luis C. Ho | First 5 Authors: Zhicheng He, Zhifu Chen, Guilin Liu, Tinggui Wang, Luis C. Ho | Summary: Galactic-wide outflows driven by active galactic nuclei (AGNs) is a routinely invoked feedback mechanism in galaxy evolution models. Hitherto, the interplay among the interstellar gas on galactic scales, the propagation of AGN outflows […]


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Effects from Dark Matter Halos on X-ray Pulsar Pulse Profiles

Posted by dbos Peking

Kavli Affiliate: Lijing Shao | First 5 Authors: Yukun Liu, Hong-Bo Li, Yong Gao, Lijing Shao, Zexin Hu | Summary: Neutron stars (NSs) can capture dark matter (DM) particles because of their deep gravitational potential and high density. The accumulated DM can affect the properties of NSs. In this work we use a general relativistic […]


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Universal Quench Dynamics of an Open Quantum System

Posted by dbos UCAS

Kavli Affiliate: Long Zhang | First 5 Authors: Chengxiang Ding, Long Zhang, , , | Summary: Taking the quantum Kitaev chain as an example, we have studied the universal dynamical behaviors resulting from quantum criticality under the condition of environmental temperature quench. Our findings reveal that when the quantum parameter is at its critical value, […]


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Respiratory Subtraction for Pulmonary Microwave Ablation Evaluation

Posted by dbos Berkeley

Kavli Affiliate: Feng Wang | First 5 Authors: Wan Li, Xinyun Zhong, Wei Li, Song Zhang, Moheng Rong | Summary: Currently, lung cancer is a leading cause of global cancer mortality, often necessitating minimally invasive interventions. Microwave ablation (MWA) is extensively utilized for both primary and secondary lung tumors. Although numerous clinical guidelines and standards […]


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