Epigenetic mechanisms governing cell type specific somatic expansion and toxicity in Huntington’s disease

Kavli Affiliate: Nathaniel Heintz | Authors: Matthew Baffuto, Kert Mätlik, Isaac Ilyashov, Maria Esterlita Siantoputri, Hasnahana Chetia, Yurie Harada, Erika Sipos, Paul Darnell, Laura Kus, Thomas Carroll, Douglas Barrows, Christina Pressl, Nicholas Didkovsky and Nathaniel Heintz | Summary: Huntington’s disease (HD) is characterized by neuronal dysfunction and degeneration that varies markedly by brain region and […]


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Evolution of star clusters with initial bulk rotation via N-body simulations

Kavli Affiliate: Rainer Spurzem | First 5 Authors: Abylay Bissekenov, Xiaoying Pang, Albrecht Kamlah, M. B. N. Kouwenhoven, Rainer Spurzem | Summary: Young star clusters can inherit bulk rotation from the molecular clouds from which they have formed. This rotation can affect the long-term evolution of a star cluster and its constituent stellar populations. In […]


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Hybrid RIS-Enhanced ISAC Secure Systems: Joint Optimization in the Presence of an Extended Target

Kavli Affiliate: Long Zhang | First 5 Authors: Yu Yao, Junhao Zhang, Pu Miao, Long Zhang, Gaojie Chen | Summary: Unlike the conventional fully-passive and fully-active reconfigurable intelligent surfaces (RISs), a hybrid RIS consisting of active and passive reflection units has recently been concerned, which can exploit their integrated advantages to alleviate the RIS-induced path […]


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Disentangling hierarchical relaxations in glass formers via dynamic eigenmodes

Kavli Affiliate: Yi Zhou | First 5 Authors: Wensi Sun, Yanshuang Chen, Wencheng Ji, Yi Zhou, Hua Tong | Summary: Hierarchical dynamics in glass-forming systems span multiple timescales, from fast vibrations to slow structural rearrangements, appearing in both supercooled fluids and glassy states. Understanding how these diverse processes interact across timescales remains a central challenge. […]


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