March 2025 – Kavli Institute Pre-Print Publications

Rare mutations implicate CGE interneurons as a vulnerable axis of cognitive deficits across psychiatric disorders

Posted by klaurent March 31, 2025March 31, 2025Columbia, This Week: Neuroscience

Kavli Affiliate: Attila Losonczy | Authors: Stephanie A Herrlinger, Jiayao Wang, Bovey Y Rao, Jonathan Chang, Joseph Gogos, Attila Losonczy and Dennis Vitkup | Summary: Neuropsychiatric disorders such as autism spectrum disorder (ASD) and schizophrenia (SCZ) share genetic risk factors, including rare high penetrance single nucleotide variants and copy number variants (CNVs), and exhibit both […]

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Constraints on Non-Thermal Pressure at galaxy cluster outskirts from a Joint SPT and XMM-Newton Analysis

Posted by March 31, 2025Chicago

Kavli Affiliate: Bradford A. Benson | First 5 Authors: Arnab Sarkar, Michael McDonald, Lindsey Bleem, Mark Bautz, Bradford A. Benson | Summary: We present joint South Pole Telescope (SPT) and XMM-Newton observations of 8 massive galaxy clusters (0.8–1.7$times$10$^{15}$ M$_{odot}$) spanning a redshift range of 0.16 to 0.35. Employing a novel SZ+X-ray fitting technique, we effectively […]

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Massive Black Holes Seeded by Dark Matter — Implications for Little Red Dots and Gravitational Wave Signatures

Posted by March 31, 2025Peking

Tingwei Shen, Xuejian Shen, Huangyu Xiao, Mark Vogelsberger, Fangzhou Jiang | Summary: [[{“value”:”Observations of supermassive black holes (SMBHs) at high redshifts challenge standard seeding scenarios. We examine a dissipative self-interacting dark matter (dSIDM) model in which gravothermal collapse leads to the formation of massive BH seeds ab initio. We utilize a semi-analytical framework to predict […]

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Rethinking Key-Value Cache Compression Techniques for Large Language Model Serving

Posted by March 31, 2025Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Wei Gao, Xinyu Zhou, Peng Sun, Tianwei Zhang, Yonggang Wen | Summary: Key-Value cache (texttt{KV} texttt{cache}) compression has emerged as a promising technique to optimize Large Language Model (LLM) serving. It primarily decreases the memory consumption of texttt{KV} texttt{cache} to reduce the computation cost. Despite the development […]

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Formation of the Little Red Dots from the Core-collapse of Self-interacting Dark Matter Halos

Posted by March 31, 2025Peking

Fangzhou Jiang, Zixiang Jiang, Haonan Zheng, Luis C. Ho, Kohei Inayoshi | Summary: [[{“value”:”We present a statistical study on the formation and growth of black holes (BHs) seeded by gravothermal core-collapse of self-interacting dark matter (SIDM) halos at high redshifts, using a semi-analytical framework based on Monte-Carlo merger trees. We demonstrate that BH formation via […]

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Formation of the Little Red Dots from the Core-collapse of Self-interacting Dark Matter Halos

Posted by March 31, 2025Peking

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Temporal and Spatial Scales of Resting-state Human Cortical Activity Throughout Lifespan

Posted by klaurent March 30, 2025March 31, 2025Hopkins, This Week: Neuroscience

Kavli Affiliate: Daeyeol Lee | Authors: John Bero IV, Colin Humphries, Yang Li, Aviral Kumar, Heungyeol Lee, Maxwell Shinn, John D. Murray, Timothy Vickery and Daeyeol Lee | Summary: Sensorimotor and cognitive abilities undergo substantial changes throughout the human lifespan, but the corresponding changes in the functional properties of cortical networks remain poorly understood. This […]

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Structural Studies of an Anti-necroptosis Viral:Human Functional Hetero-amyloid M45:RIPK3 using SSNMR

Posted by klaurent March 29, 2025March 31, 2025Columbia, This Week: Neuroscience

Kavli Affiliate: Ann McDermott | Authors: Chengming He, Nikhil R Varghese, Eric G Keeler, Chi L L Pham, Brayden Williams, Stephan Tetter, Crystal Semaan, Karyn L Wilde, Simon H J Brown, James C Bouwer, Yann Gambin, Emma Sierecki, Megan Steain, Margaret Sunde and Ann E McDermott | Summary: The formation of RIP-homotypic interaction motif (RHIM)-based […]

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Haplotype-resolved reference genomes of the sea turtle clade unveil ultra-syntenic genomes with hotspots of divergence

Posted by klaurent March 28, 2025March 31, 2025Rockefeller, This Week: Neuroscience

Kavli Affiliate: Erich Jarvis | Authors: Larissa S. Arantes, Tom Brown, Diego De Panis, Scott D. Whiting, Erin L. LaCasella, Gabriella A. Carvajal, Adam Kennedy, Deana Edmunds, Blair P. Bentley, Jennifer Balacco, Conor Whelan, Nivesh Jain, Tatiana Tilley, Brian O’Toole, Patrick Traore, Erich D. Jarvis, Oliver Berry, Peter H. Dutton, Lisa M. Komoroske and Camila […]

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dolphin: A fully automated forward modeling pipeline powered by artificial intelligence for galaxy-scale strong lenses

Posted by klaurent March 28, 2025March 31, 2025Chicago, This Week: Astrophysics

Kavli Affiliate: Joshua Frieman | First 5 Authors: Anowar J. Shajib, Nafis Sadik Nihal, Chin Yi Tan, Vedant Sahu, Simon Birrer | Summary: Strong gravitational lensing is a powerful tool for probing the internal structure and evolution of galaxies, the nature of dark matter, and the expansion history of the Universe, among many other scientific […]

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