The conserved N-terminal SANT1-binding domain (SBD) of EZH2 Regulates PRC2 Activity

Posted by dbos Rockefeller

Kavli Affiliate: C. David Allis | Authors: Agata Lemiesz Patriotis, Yadira Soto-Feliciano, Douglas Barrows, Laiba Khan, Marylene Leboeuf, Peder Lund, Matthew R Marunde, Annaelle Djomo, Michael-Christopher Keogh, Thomas Carroll, Benjamin Garcia, Alexey A Soshnev and C. David Allis | Summary: Polycomb group proteins maintain gene expression patterns established during early development, with Polycomb Repressive Complex […]


Continue.. The conserved N-terminal SANT1-binding domain (SBD) of EZH2 Regulates PRC2 Activity

Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics

Posted by dbos UCSF

Kavli Affiliate: Michael Keiser | Authors: Parker Grosjean, Kaivalya Shevade, Cuong Nguyen, Sarah Ancheta, Karl Mader, Ivan Franco, Seok-Jin Heo, Greyson Lewis, Steven Boggess, Angelique De Domenico, Erik Ullian, Shawn Shafer, Adam Litterman, Laralynne Przybyla, Michael J Keiser, Jamie Ifkovits, Adam Yala and Martin Kampmann | Summary: High-throughput phenotypic screening has historically relied on manually […]


Continue.. Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics

Universal machine learning interatomic potentials poised to supplant DFT in modeling general defects in metals and random alloys

Posted by dbos Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Fei Shuang, Zixiong Wei, Kai Liu, Wei Gao, Poulumi Dey | Summary: Recent advances in machine learning, combined with the generation of extensive density functional theory (DFT) datasets, have enabled the development of universal machine learning interatomic potentials (uMLIPs). These models offer broad applicability across the periodic […]


Continue.. Universal machine learning interatomic potentials poised to supplant DFT in modeling general defects in metals and random alloys

Probing intermediate-mass black hole binaries with the Lunar Gravitational-wave Antenna

Posted by dbos Peking

Kavli Affiliate: Lijing Shao | First 5 Authors: Hanlin Song, Han Yan, Yacheng Kang, Xian Chen, Junjie Zhao | Summary: New concepts for observing the gravitational waves (GWs) using a detector on the Moon, such as the Lunar Gravitational-wave Antenna (LGWA), have gained increasing attention. By utilizing the Moon as a giant antenna, the LGWA […]


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Thermoelastic Damping Across the Phase Transition in van der Waals Magnets

Posted by dbos Berkeley

Kavli Affiliate: Xiang Zhang | First 5 Authors: Alvaro Bermejillo-Seco, Xiang Zhang, Maurits J. A. Houmes, Makars Šiškins, Herre S. J. van der Zant | Summary: A quantitative understanding of the microscopic mechanisms responsible for damping in van der Waals nanomechanical resonators remains elusive. In this work, we investigate van der Waals magnets, where the […]


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Propagation-induced Frequency-dependent Polarization Properties of Fast Radio Burst

Posted by dbos Peking

Kavli Affiliate: Renxin Xu | First 5 Authors: Wei-Yang Wang, Xiaohui Liu, Dongzi Li, Bing Zhang, Chen-Hui Niu | Summary: Frequency-dependent polarization properties provide crucial insights into the radiation mechanisms and magnetic environments of fast radio bursts (FRBs). We explore an analytical solution of radiative transfer of the polarization properties of FRBs as a strong […]


Continue.. Propagation-induced Frequency-dependent Polarization Properties of Fast Radio Burst