Kavli Affiliate: Xingde Li | Authors: Yuehan Liu, Jiayun Laurie Huang and Xingde Li | Summary: Miniaturized two-photon imaging devices enable real-time in vivo and in situ imaging at subcellular resolution, highly valuable for clinical applications and basic research (such as neuroscience). However, achieving high-quality volumetric imaging at varying depths remains challenging. In this study, […]
Kavli Affiliate: Alexander P. Ji | First 5 Authors: Kaley Brauer, Jennifer Mead, John H. Wise, Greg L. Bryan, Mordecai-Mark Mac Low | Summary: We explore the effect of variations in the Population III (Pop III) initial mass function (IMF) and star-by-star feedback on early galaxy formation and evolution using the Aeos simulations. We compare […]
Kavli Affiliate: Anna Molofsky and Christoph Kirst | Authors: Haruna Nakajo, Ran Cao, Supriya A. Mula, Justin McKetney, Nicholas J. Silva, Muskaan Shah, Indigo V.L. Rose, Martin Kampmann, Danielle L. Swaney, Christoph Kirst and Anna V. Molofsky | Summary: Maintaining a dynamic neuronal synapse pool is critical to brain development. The extracellular matrix (ECM) regulates […]
Kavli Affiliate: Reza Abbasi Asl | Authors: Alex Jihun Lee, Shenqin Yao, Nicholas Lusk, Hongkui Zeng, Bosiljka Tasic and Reza Abbasi-Asl | Summary: Spatial transcriptomics offers unique opportunities to define the spatial organization of tissues and organs, such as the mouse brain. We address a key bottleneck in the analysis of organ-scale spatial transcriptomic data […]
Kavli Affiliate: Anirvan Nandy | Authors: Mary Kate P Joyce, Tsvetoslav G Ivanov, Fenna Krienen, Jude Mitchell, Shaojie Ma, Wataru Inoue, Anirvan P Nandy, Dibyadeep Datta, Alvaro Duque, Jon I Arellano, Rahul Gupta, Guillermo Gonzalez-Burgos, David A Lewis, Nenad Sestan, Steven A McCarroll, Julio C Martinez-Trujillo, Seán Froudist-Walsh and Amy FT Arnsten | Summary: Marmosets […]
Kavli Affiliate: Pietro De Camilli and Shawn Ferguson | Authors: Xinbo Wang, Peng Xu, Amanda Bentley-DeSousa, William Hancock-Cerutti, Shujun Cai, Benjamin T Johnson, Francesca Tonelli, Lin Shao, Gabriel Talaia, Dario R Alessi, Shawn M Ferguson and Pietro De Camilli | Summary: Based on genetic studies, lysosome dysfunction is thought to play a pathogenetic role in […]
Kavli Affiliate: Jinyi Shangguan | First 5 Authors: Yan-Rong Li, Jinyi Shangguan, Jian-Min Wang, Ric Davies, Daryl J. Santos | Summary: The geometric distances of active galactic nuclei (AGNs) are challenging to measure because of their exceptionally compact structure yet vast cosmic distances. A combination of spectroastrometry and reverberation mapping (SARM) of broad-line regions (BLRs) […]
Kavli Affiliate: Li Zhao | Authors: Guoyang Zhou, Jian He, Baojie Mao, Guo Cheng, Rui Zhang, Qiang Wang, Xiaoli Liu, Jiaxin Zheng, Ming Wang, Li Zhao, Peng Shi, Xiao Z Shen and Shu Wan | Summary: The interconnected ventricles in the central nervous system are filled with cerebrospinal fluid (CSF) which serves multifaceted roles including […]
Kavli Affiliate: Leslie B. Vosshall | Authors: Olivia V. Goldman, Alexandra E. DeFoe, Yanyan Qi, Yaoyu Jiao, Shih-Che Weng, Leah Houri-Zeevi, Priyanka Lakhiani, Takeshi Morita, Jacopo Razzauti, Adriana Rosas-Villegas, Yael N. Tsitohay, Madison M. Walker, Ben R. Hopkins, Mosquito Cell Atlas Consortium, Omar S. Akbari, Laura B. Duvall, Helen White-Cooper, Trevor R. Sorrells, Roshan Sharma, […]
Kavli Affiliate: Nathaniel Heintz | Authors: Tatsuya C. Murakami, Nick Belenko, Griffin Dennis, Cuidong Wang, Maria Esterlita Siantoputri, Yurie Maeda, Christina Pressl and Nathaniel Heintz | Summary: Fluorescent imaging enables visualization of the specific molecules of interest with high contrast, and the use of multiple fluorophores in a single tissue sample allows visualization of complex […]