Mitigating Forgetting in LLM Supervised Fine-Tuning and Preference Learning

Kavli Affiliate: Yi Zhou | First 5 Authors: Heshan Fernando, Han Shen, Parikshit Ram, Yi Zhou, Horst Samulowitz | Summary: Post-training of pre-trained LLMs, which typically consists of the supervised fine-tuning (SFT) stage and the preference learning (RLHF or DPO) stage, is crucial to effective and safe LLM applications. The widely adopted approach in post-training […]


Continue.. Mitigating Forgetting in LLM Supervised Fine-Tuning and Preference Learning

Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates

Kavli Affiliate: Keri Martinowich | Authors: Michael S Totty, Rita Cervera-Juanes, Svitlana V Bach, Lamya Ben Ameur, Madeline R Valentine, Evan Simons, Mckenna D Romac, Hoa Trinh, Krystal Henderson, Ishbel Del Rosario, Madhavi Tippani, Ryan A Miller, Joel E Kleinman, Stephanie Cerceo Page, Arpiar Saunders, Thomas M Hyde, Keri Martinowich, Stephanie C Hicks and Vincent […]


Continue.. Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates

ybx1 acts upstream of atoh1a to promote the rapid regeneration of hair cells in zebrafish lateral-line neuromasts

Kavli Affiliate: A. James Hudspeth | Authors: Caleb C. Reagor and A. J. Hudspeth | Summary: Like the sensory organs of the human inner ear, the lateral-line neuromasts (NMs) of fish such as the zebrafish (Danio rerio) contain mechanosensory hair cells (HCs) that are surrounded by progenitors called supporting cells. Damaged NMs can quickly regenerate […]


Continue.. ybx1 acts upstream of atoh1a to promote the rapid regeneration of hair cells in zebrafish lateral-line neuromasts

Gut bacteria-derived succinate induces enteric nervous system regeneration

Kavli Affiliate: Daniel Mucida | Authors: Begüm Aydin, Izabela Mamede, Joana Cardoso, Julia Deere, Yelina Alvarez, Shanshan Qiao, Ved P. Sharma, Marissa A. Scavuzzo, Gregory P. Donaldson, Chun-Jun Guo and Daniel Mucida | Summary: Enteric neurons control gut physiology by regulating peristalsis, nutrient absorption, and secretion. Disruptions in microbial communities caused by antibiotics or enteric […]


Continue.. Gut bacteria-derived succinate induces enteric nervous system regeneration

Why do bats fly into cave doors? Inattentional blindness in echolocating animals

Kavli Affiliate: Cynthia F. Moss | Authors: Nikita M Finger, Keegan E Eveland, Xiaoyan Yin and Cynthia F Moss | Summary: Echolocating bats can navigate complex 3D environments by integrating prior knowledge of spatial layouts and real-time sensory cues. This study demonstrates that inattentional blindness to sensory information undermines successful navigation in Egyptian fruit bats, […]


Continue.. Why do bats fly into cave doors? Inattentional blindness in echolocating animals

Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer’s disease

Kavli Affiliate: Arnold R. Kriegstein | Authors: Beika Zhu, Andi Wangzhou, Diankun Yu, Tao Li, Rachael Schmidt, Stacy L. De Florencio, Lauren Chao, Yonatan Perez, Lea Tenenholz Grinberg, Salvatore Spina, Richard M Ransohoff, Arnold Kriegstein, William W Seeley, Tomasz J. Nowakowski and Xianhua Piao | Summary: Germline genetic architecture of Alzheimer’s disease (AD) indicates microglial […]


Continue.. Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer’s disease

Early Bright Galaxies from Helium Enhancements in High-Redshift Star Clusters

Kavli Affiliate: Alexander P. Ji | First 5 Authors: Harley Katz, Alexander P. Ji, O. Grace Telford, Peter Senchyna, | Summary: The first few cycles of JWST have identified an overabundance of UV-bright galaxies and a general excess of UV luminosity density at $zgtrsim10$ compared to expectations from most (pre-JWST) theoretical models. Moreover, some of […]


Continue.. Early Bright Galaxies from Helium Enhancements in High-Redshift Star Clusters

Early Bright Galaxies from Helium Enhancements in High-Redshift Star Clusters

Kavli Affiliate: Alexander P. Ji | First 5 Authors: Harley Katz, Alexander P. Ji, O. Grace Telford, Peter Senchyna, | Summary: The first few cycles of JWST have identified an overabundance of UV-bright galaxies and a general excess of UV luminosity density at $zgtrsim10$ compared to expectations from most (pre-JWST) theoretical models. Moreover, some of […]


Continue.. Early Bright Galaxies from Helium Enhancements in High-Redshift Star Clusters

The disappearance of a massive star marking the birth of a black hole in M31

Kavli Affiliate: Erin Kara | First 5 Authors: Kishalay De, Morgan MacLeod, Jacob E. Jencson, Elizabeth Lovegrove, Andrea Antoni | Summary: Stellar mass black holes are formed from the terminal collapse of massive stars if the ensuing neutrino shock is unable to eject the stellar envelope. Direct observations of black hole formation remain inconclusive. We […]


Continue.. The disappearance of a massive star marking the birth of a black hole in M31